Admission of Burn Patients to the Burn Center Including Burn Wound Evaluation

Elmasry, Moustafa; Steinvall, Ingrid; Olofsson, Patrik; Sjöberg, Folke

doi:10.1007/978-3-030-18940-2_13

Cited by 1 publication

(1 citation statement)

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“…The wound coverings of biologically derived tissue, such as the skins of pigs, Nile tilapia, and cadaver have long been used as xenografts for the treatment of burns [6,24,25].…”

Section: Discussionmentioning

confidence: 99%

Therapeutic Treatment of 2A Grade Burns with Decellularized Bovine Peritoneum as a Xenograft: Multicenter Randomized Clinical Trial

et al. 2022

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Background and Objectives: Homogeneous and xenogenic bioengineering structures are actively used as wound coatings in treatment of burns and have already shown their effectiveness. Nevertheless, the disadvantage of such dressings is their high cost. This issue is particularly challenging for developing countries in which the incidence of burns is the highest one. With such needs taken into account, the research team developed and clinically tested a new wound coating based on decellularized bovine peritoneum (DBP). Materials and Methods: A multicenter randomized clinical trial was conducted to evaluate DBP. The following variables were considered in the research study: the number of inpatient days, the number of dressing changes, the level of pain experienced during dressing changes, and the condition of wounds at the time of the follow-up examination. Results: The research involved 68 participants. It was found that the patients who were treated with a DBP experienced less pain with less changes of dressings. However, the number of inpatient days and wound healing failed to demonstrate statistically significant difference compared to the control group. Conclusions: In the given research, DBP showed efficacy in improving patients’ quality of life by reducing pain and the number of dressings’ changes. However, when comparing this research study with the studies of other animal-derived wound coverings, there were a number of differences and limitations in the parameters. Thus, the results requires further study for a greater comparability of data. Given the above, we expect that DBP will become an inexpensive and effective treatment for burns in developing countries.

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“…The wound coverings of biologically derived tissue, such as the skins of pigs, Nile tilapia, and cadaver have long been used as xenografts for the treatment of burns [6,24,25].…”

Section: Discussionmentioning

confidence: 99%