“…In terms of candidates for within-session active ingredients, in contrast with other putative mechanisms (Apodaca and Longabaugh, 2009;Longabaugh and Wirtz, 2001), change talk (client statements in favor of change) has gained the most consistent support for its relationship with substance use outcomes across MI (Amrhein et al, 2003;Apodaca and Longabaugh, 2009;Baer et al, 2008;Daeppen et al, 2010;Gaume et al, 2008;Martin et al, 2011;Moyers et al, 2007Moyers et al, , 2009Strang and McCambridge, 2004;Vader et al, 2010;Walker et al, 2011), as well as across other psychosocial interventions (Aharonovich et al, 2008;Hodgins et al, 2009;Karno et al, 2010;Moyers et al, 2007). Together, these data suggest that change talk is the most relevant target for mechanism research in MI (Miller and Rose, 2009), and it therefore serves as the focus of this review.…”