Adrenal Extramedullary Hematopoiesis: A Case Report

Abstract

An adrenal incidentaloma is a mass lesion greater than 1 cm in diameter, serendipitously discovered by radiologic examination. Extramedullary hematopoiesis presenting as adrenal mass is not a common entity but foci of Extramedullary Hematopoiesis (EMH) may occur in almost any organ.

A rare case of adrenal extramedullary haematopoiesis in a Cypriot woman with β-thalassaemia

“… 2 , 3 As reported by Keikhaei et al , 4 EMH is caused by a long-standing response due to severe chronic anaemia. Maryam et al 2 reported haemolytic anaemia and myelofibrosis as a cause of EMH. The most common sites of EMH are reported 2 , 3 to be the spleen, liver, lymph nodes, lung, pleura, breast, thymus, small bowel and central nervous system.…”

“…When haematopoiesis occurs outside the bone marrow it is referred to as extramedullary haematopoiesis (EMH). 2 EMH occurs secondarily to altered bone marrow function and subsequent abnormal haematopoiesis. 2 , 3 As reported by Keikhaei et al , 4 EMH is caused by a long-standing response due to severe chronic anaemia.…”

“… 2 EMH occurs secondarily to altered bone marrow function and subsequent abnormal haematopoiesis. 2 , 3 As reported by Keikhaei et al , 4 EMH is caused by a long-standing response due to severe chronic anaemia. Maryam et al 2 reported haemolytic anaemia and myelofibrosis as a cause of EMH.…”

“…Maryam et al 2 reported haemolytic anaemia and myelofibrosis as a cause of EMH. The most common sites of EMH are reported 2 , 3 to be the spleen, liver, lymph nodes, lung, pleura, breast, thymus, small bowel and central nervous system. EMH is rarely found in the kidneys and adrenal glands.…”

“…Haemoglobinopathies, haemolytic anaemias (such as thalassaemia), leukaemias, lymphomas and myeloproliferative disorders are examples of conditions that have reported complications of adrenal EMH requiring surgery. 2 Imaging and adrenal hormonal investigations are important to exclude malignancy and subclinical hypersecretory syndromes. 3 …”