Adrenal myelolipoma: A rare lesion of adrenal gland

Baisakh,; Chattoraj, A; Narayanan, Radhika; Mohanty, Rajesh; Mishra, Meenakshi

doi:10.4103/0019-509x.178402

Cited by 5 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Myelolipoma is a rare benign tumor of mesenchymal origin that consists of mature adipose tissue and marrow components in various proportions. [13] The vast majority of myelolipomas occur in the adrenal gland, and extra-adrenal myelolipomas are not common. Currently, the documented sites include the pleura, [14] lung, [15] presacral area, [16] thoracic spine, [17] right iliac fossa, [18] mediastinum, [19] and retroperitoneum perirenal tissue.…”

Section: Discussionmentioning

confidence: 99%

MR imaging to detect myelolipomas of the liver

Xin

et al. 2019

Medicine

View full text Add to dashboard Cite

Rationale: Primary hepatic myelolipoma is a rare benign neoplasm comprising mature adipose tissue and marrow components in various proportions. Chemical shift imaging (CSI) can distinguish the lipid within the tumor clearly; however, there have been no reports on the CSI of hepatic myelolipoma. Patient concern: A 20-year-old woman visited our hospital after discovering a space-occupying lesion in the liver with a history of more than 1 year. She felt distension pain and discomfort under the xiphoid process, accompanied by nausea, vomiting, and occasional chest oppression. Diagnosis: The tumor showed a well-defined mass with a pseudocapsule and a heterogeneous appearance on both T1- and T2-weighted magnetic resonance (MR) images. CSI analysis showed a signal decline within the tumor. Based on the histopathology, the tumor was diagnosed as hepatic myelolipoma. Interventions and Outcomes: The patient underwent a right hepatectomy, and the postoperative vital signs were stable. Two weeks later, the patient was discharged safely. Lessons: Although hepatic myelolipoma is extremely rare, this condition should be considered in differential diagnosis when CSI shows that hepatic lesions contain fatty.

show abstract

Section: Discussionmentioning

confidence: 99%

MR imaging to detect myelolipomas of the liver

Xin

et al. 2019

Medicine

View full text Add to dashboard Cite

show abstract

“…Myelolipoma is a rare type of benign, nonfunctioning tumor of mesenchymal origin, which is composed of various proportions of fat and hematopoietic cells[14]. As such, it resembles a site of extramedullary hematopoiesis.…”

Section: Discussionmentioning

confidence: 99%

Synchronous occurrence of a hepatic myelolipoma and two hepatocellular carcinomas

Xu¹,

Xie²,

Zhou³

et al. 2016

WJG

View full text Add to dashboard Cite

Myelolipoma is a rare tumor composed of fat and bone marrow components, most of which are located in the adrenal gland. Myelolipoma in the liver is extremely rare. To date, only 10 cases have been reported in the English-language medical literature. In one of these cases, the hepatic myelolipoma was found within a hepatocellular carcinoma (HCC). In the present study, we report the first case of the synchronous occurrence of hepatic myelolipoma and HCCs in different liver sections of one patient, a 26-year-old female who was admitted to our hospital because of a 4-d history of upper abdominal pain. The unenhanced computed tomography (CT) images showed a well-defined low-density mass with adipose components in the right liver lobe, 4.2 cm × 4.1 cm in size. Two inhomogeneous low-density masses were found in the left liver lobe, 8.6 cm × 7.7 cm and 2.6 cm × 2.6 cm in size. The masses in both the right and left liver lobes were heterogeneously enhanced in the contrast-enhanced CT images. Based on the results of the imaging examination, the mass in the right liver lobe was preliminarily considered to be a hamartoma, and the two masses in the left liver were preliminarily considered to be HCCs. We performed a right hepatectomy, a left hepatic lobectomy, and a cholecystectomy. Microscopic and immunohistochemical results revealed that the tumor in the right liver lobe was a hepatic myelolipoma, and that the two tumors in the left liver lobe were HCCs.

show abstract

“…The most frequent neoplasia with adrenal involvement is breast or lung cancer, and lymphomas [ 14 , 15 , 16 ]. Other rare adrenal lesions especially with tumor appearance are myelolipoma, neurofibroma, hamartoma, xanthomatosis, amyloidosis, granulomatosis [ 17 , 18 , 19 ]. The adrenal bed may locate masses of non-adrenal origin, like those arising from the pancreas, spleen or kidney and rarely imagery artefacts need to be differentiated [ 20 , 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

Cystic adrenal lesions: focus on pediatric population (a review)

Cârșote

Ghemigian

Terzea

et al. 2017

Medicine and Pharmacy Reports

View full text Add to dashboard Cite

Background and aimThe cysts may potentially affect any organ; adrenals cysts are rare. This is a review of the literature regarding adrenal cysts, focusing on children and young adults.General dataThree major types have been described: pure cysts (endothelial, epithelial, and hemorrhagic or pseudocyst), parasitic (as hydatid) cysts and cystic part of a tumour (most frequent are neuroblastoma, ganglioneuroma, pheocromocytoma, and teratoma). The complications are: bleeding, local pressure effects; infection; rupture (including post-traumatic); arterial hypertension due to renal vessels compression. Adrenal hemorrhage represents a particular condition associating precipitating factors such as: coagulation defects as Factor IX or X deficiency, von Willebrand disease, thrombocytopenia; antiphospholipid syndrome; previous therapy with clopidogrel or corticosteroids; the rupture of a prior tumour. At birth, the most suggestive features are abdominal palpable mass, anemia, and persistent jaundice. Adrenal insufficiency may be found especially in premature delivery. The hemorrhage is mostly self-limiting. Antenatal ultrasound diagnosis of a cyst does not always predict the exact pathology result. The most important differential diagnosis of adrenal hemorrhage/hemorrhagic cyst is cystic neuroblastoma which is highly suggestive in the presence of distant metastases and abnormal catecholamine profile. The major clue to differentiate the two conditions is the fact that the tumor is stable or increases over time while the adrenal hemorrhage is expected to remit within one to two weeks.ConclusionPediatric adrenal cysts vary from simple cysts with a benign behavior to neoplasia- related lesions displaying severe prognosis as seen in cystic neuroblastoma. A multidisciplinary team is required for their management which is conservative as close follow-up or it makes necessary different surgical procedures in cases with large masses or if a malignancy suspicion is presented. Recently, laparoscopic approach is regarded as a safe procedure by some authors but generally, open surgery is more frequent used compare to adults; in most cases the preservation of normal gland is advisable.

show abstract

Adrenal myelolipoma: A rare lesion of adrenal gland

Cited by 5 publications

References 0 publications

MR imaging to detect myelolipomas of the liver

MR imaging to detect myelolipomas of the liver

Synchronous occurrence of a hepatic myelolipoma and two hepatocellular carcinomas

Cystic adrenal lesions: focus on pediatric population (a review)

Contact Info

Product

Resources

About