Adsorption and release of biocides with mesoporous silica nanoparticles

Abstract

In this proof-of-concept study, an agricultural biocide (imidacloprid) was effectively loaded into the mesoporous silica nanoparticles (MSNs) with different pore sizes, morphologies and mesoporous structures for termite control. This resulted in nanoparticles with a large surface area, tunable pore diameter and small particle size, which are ideal carriers for adsorption and controlled release of imidacloprid. The effect of pore size, surface area and mesoporous structure on uptake and release of imidacloprid was systematically studied. It was found that the adsorption amount and release profile of imidacloprid were dependent on the type of mesoporous structure and surface area of particles. Specifically, MCM-48 type mesoporous silica nanoparticles with a three dimensional (3D) open network structure and high surface area displayed the highest adsorption capacity compared to other types of silica nanoparticles. Release of imidacloprid from these nanoparticles was found to be controlled over 48 hours. Finally, in vivo laboratory testing on termite control proved the efficacy of these nanoparticles as delivery carriers for biopesticides. We believe that the present study will contribute to the design of more effective controlled and targeted delivery for other biomolecules.

Towards using of new and safety material against tomato leafminer,Tuta absoluta(Mayrick)

“…Cidal effect of silica (Si) and chlorantraniliprole (Cp) alone and in combination to the 2nd instar larvae of T. absoluta. The same result was found by Popat et al (2012). The authors found that the percent of termite mortality was increased when imidacloprid mixed with mesoporous silica nanoparticles and also, become effective during 48 h. Luz et al (2012) mixed the conidia of Metarrhizium anisopliae fungi formulation with DE and a vegetable oil against Peridomestic triatomine bugs.…”

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

“…In particular, Mesoporous Silica Nanoparticles (MSNs), such as MCM-41 have desirable properties including ease of synthesis and surface functionalisation, large surface area, and excellent in vivo biocompatibility [26]. The controllable pore structures make MSNs excellent candidates to tune the adsorption and release of biomolecules [27]. A few studies on the potential of MSNs as vaccine adjuvants and antigen carriers have been explored [25,28,29].…”

Adsorption of hydrogen peroxide on functionalized mesoporous silica surfaces

“…Mesoporous materials developed in the 1990s, show numerous advantages: large surface area (*1,000 m 2 /g), uniform and controllable pore size, large pore volume (*1 cm 3 /g), narrow particle size, open pore structures [24], chemical and biological stability, and possibility of control of surface functionalization, which makes them very useful in a wide variety of applications such as adsorption, catalysis, ion exchange, sensing [25], chromatography [26], delivery carriers, and controlled drug/gene release [27]. There are three general paths to achieve surface functionalization of mesoporous silica surface [28]: postsynthetic functionalization (the so-called ''grafting'') and two methods involved in the silica preparation process-co-condensation and condensation of bridged organosilica precursors forming periodic mesoporous organosilicas.…”