Adsorption behavior of some metal ions on nanoparticles used in pharmaceutical matrices: Application to laboratory made drug formulation

Ragab, Marwa A.A.; Korany, Mohamed A.; Ibrahim, Hayam M.; Abdel-Kawi, Mervat A.; Sayed, Abd El Aal A. A.

doi:10.1016/j.bfopcu.2017.01.002

Cited by 14 publications

(10 citation statements)

References 17 publications

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“…One of the most important factors in the adsorption process that influence the silica adsorbent-adsorbate interactions is the pH of the solution, due to its ability to change the ionic state of the analytes as well as the surface charge of adsorbent [37]. The effects of the pH on the extraction of Cu, Cd, Co, Cr, Pb, and Zn ions as an adsorbate on Gly-, IDA-, and AP-functionalized MSNs were investigated in the pH range of 3-9.…”

Section: Adsorption Studiesmentioning

confidence: 99%

Evaluation of the Adsorption Efficiency of Glycine-, Iminodiacetic Acid -, and Amino Propyl-Functionalized Silica Nanoparticles for the Removal of Potentially Toxic Elements from Contaminated Water Solution

Alswieleh

Albahar

AlFawaz

et al. 2021

Journal of Nanomaterials

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In present work, mesoporous silica nanoparticles (MSNs) were prepared with a surface area of 1048 m2g-1 and a large pore size of ca. 6 nm, using Stöber process in the presence of expanding reagent ( n -hexane). The surface of MSNs was modified with three different functional groups (amine, iminodiacetic acid, and glycine) and characterized by a variety of physicochemical techniques. The adsorption studies were carried out at different pH values in two extraction systems. In batch method, the maximum adsorption efficiency of heavy metals was measured to be 95% for all fabricated MSNs at pH 9. At pH 3, the adsorption efficiency of Pb and Cu was observed to be affected by the carboxylic moiety involved in the functional group. As the number of carboxylic moieties increase, the removal efficiency of Pb and Cu ions increased by two folds. The results demonstrated the selectivity of IDA-MSNs for the removal of Pb and Cu ions, even though the multielements are present in an aqueous solution. On the other hand, the incorporation of MSNs into the polymeric membrane showed high water permeability ( 9.96 ± 3 L / m 2 . h . bar ), and 98% rejection was achieved at pH 7 for Cu+2 and Pb+2 ions.

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Section: Adsorption Studiesmentioning

confidence: 99%

Evaluation of the Adsorption Efficiency of Glycine-, Iminodiacetic Acid -, and Amino Propyl-Functionalized Silica Nanoparticles for the Removal of Potentially Toxic Elements from Contaminated Water Solution

Alswieleh

Albahar

AlFawaz

et al. 2021

Journal of Nanomaterials

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“…Tin was found in the collected fractions suggesting that tin could be bound onto silica nanoparticles. Electrostatic interaction and strong coordinate bonds between adsorbed tin ions with weak acidity of hydroxyl from silanol groups on silica nanoparticles surface has known to be suitable adsorption mechanism (Ragab et al 2017). Carrier solution flow did not ruin the interaction between tin with silica nanoparticles as we could see tin intensity in the collected fractions.…”

Section: Relative Fractionation Recoverymentioning

confidence: 70%

“…In the presence of silica nanoparticles as food additive in canned food, dissolved tin would also be possible to bind onto silica nanoparticles. Several researchers have investigated the adsorption behavior of metal onto silica nanoparticles (Karnib et al 2014;Ragab et al 2017), and their adsorption of metal immensely enhanced the toxicity (Ragab et al 2017). However, the adsorption behavior of tin onto silica nanoparticles has never been reported.…”

Section: Introductionmentioning

confidence: 99%

“…Assessment of adsorbed metal onto nanoparticles includes two steps, i.e., the separation of nanoparticles and the detection of metal residual by element determination techniques such as flame atomic absorption spectrometry (FAAS) or electrothermal atomic absorption spectrometry (ETAAS) (Karnib et al 2014;Ragab et al 2017). Field-flow fractionation (FFF) is a separation technique which has great ability for separating particles, molecules, and colloids in the range of nanometers up to micrometers.…”

Section: Introductionmentioning

confidence: 99%

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Investigation of tin adsorption on silica nanoparticles by using flow field-flow fractionation with offline inductively coupled plasma mass spectrometry

Zulfah

Siripinyanond

2018

J Anal Sci Technol

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Flow field-flow fractionation (Fl-FFF) for silica nanoparticles with offline inductively coupled plasma mass spectrometry (ICP-MS) was applied to investigate the adsorption behavior of tin onto silica nanoparticles. Effect of carrier solutions and membranes was studied to achieve better separation for silica nanoparticles prior to tin detection using ICP-MS. Investigation was carried out by using 0.25 mM ammonium carbonate and 0.02% FL-70 with 0.02% NaN 3 as carrier solutions with 1 kDa regenerated cellulose (RC), 10 kDa regenerated cellulose (RC), and 10 kDa polyethersulfone (PES) membranes. Ammonium carbonate carrier solution with suitable ionic strength provided good separation with minimization of particle-membrane interaction. Better retention was shown by employing 10 kDa RC membrane. Furthermore, Fl-FFF was employed for the separation of silica nanoparticles incubated with tin. Fractions eluted from Fl-FFF were collected and then introduced into ICP-MS. Tin was adsorbed onto silica nanoparticles with different adsorption capabilities depending on particle size. Adsorption of tin was greater on the smaller size of silica nanoparticles compared to the bigger size with the adsorption percentage of 98.5, 44.9, and 6.5 for 60 nm, 100 nm, and 200 nm, respectively. Size-dependent adsorption of tin was in good agreement with surface area per volume of silica nanoparticles.

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“…The particles of both oxides remaining in water are in a continuous contact with Ca 2+ in the soil environment. Remembering that assemblages of these oxides from the industry sector are still released into the natural system (Kasprzyk-Hordern 2004;Lee et al 2010), research on their behavior towards calcium ions was carried out over the past decades (Roach and Himmelblau 1961;Huang and Stumm 1973;Meng and Letterman 1993;Brigante and Avena 2016;Ragab et al 2017;Wan et al 2019). For example, Tadros and Lyklema (1969) investigated calcium adsorption on silica using potentiometric titrations and the Eppendorf flame photometer.…”

Section: Introductionmentioning

confidence: 99%

Investigations of mechanism of Ca2+ adsorption on silica and alumina based on Ca-ISE monitoring, potentiometric titration, electrokinetic measurements and surface complexation modeling

2020

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Research on Ca2+ adsorption onto the mineral surface is of significant importance with regard to geochemical processes. Sverjensky (Geochim Cosmochim Acta 70(10), 2427–2453, 2006) assumed that alkaline earths form two types of surface species on oxides: tetranuclear (> SOH)2(> SO−)2_M(OH)+ and mononuclear > SO−_M(OH)+. To look into the above assumption we investigated calcium adsorption on SiO2 and Al2O3 because they are the most widespread minerals in the environment. We have determined the proton surface charge, electrokinetic potential and metal adsorption as a function of pH. The Ca2+ uptake and concentration in the system were monitored by the calcium ion-selective electrode (Ca-ISE). The Ca-ISE measurements indicated a similar affinity of Ca2+ for both materials despite their differently charged surface, negative for silica and mainly positive for alumina. This may suggest that simple electrostatic interactions are not the primary driving force for calcium adsorption, and that solvation of calcium ions at the surface may be crucial. We have analyzed our experimental data using the 2-pK triple-layer model (2-pK TLM). Three calcium complexes on the mineral surface were reported. Two of them were the same for both oxides, i.e. the tetranuclear ($$>$$ > SOH)2($$>$$ > SO−)2_Ca2+ and mononuclear complexes > SO−_CaOH+. Additionally, minor contribution from >SOH…Ca2+ for silica was assumed. In the case of Al2O3 the hydrolyzed tetranuclear complexes ($$>$$ > SOH)2($$>$$ > SO−)2_CaOH+ at pH > 7.5 occurred based on the modeling results. Two types of surface complexes suggested by Sverjensky allowed for the correct description of proton and calcium uptake for alumina. However, the electrokinetic data excluded hydrolyzed tetranuclear surface species for this oxide.

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Adsorption behavior of some metal ions on nanoparticles used in pharmaceutical matrices: Application to laboratory made drug formulation

Cited by 14 publications

References 17 publications

Evaluation of the Adsorption Efficiency of Glycine-, Iminodiacetic Acid -, and Amino Propyl-Functionalized Silica Nanoparticles for the Removal of Potentially Toxic Elements from Contaminated Water Solution

Evaluation of the Adsorption Efficiency of Glycine-, Iminodiacetic Acid -, and Amino Propyl-Functionalized Silica Nanoparticles for the Removal of Potentially Toxic Elements from Contaminated Water Solution

Investigation of tin adsorption on silica nanoparticles by using flow field-flow fractionation with offline inductively coupled plasma mass spectrometry

Investigations of mechanism of Ca2+ adsorption on silica and alumina based on Ca-ISE monitoring, potentiometric titration, electrokinetic measurements and surface complexation modeling

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