Adsorption of active ingredients of surface disinfectants depends on the type of fabric used for surface treatment

Bloss, R; Meyer, Steven De; Kampf, Günter

doi:10.1016/j.jhin.2009.11.027

Cited by 26 publications

(18 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16 With the number of biocidal formulations and materials available today, the impact of different material on formulation has yet received little attention, although the percentage of a biocidal formulations adsorbed on different material can be significant. 17 One of the most important change in recent years was the introduction of efficacy test protocols that reflected the use of a product rather than a formulation. 15 The introduction of the purposely designed antimicrobial wipe test the EN16615-15 18 "four field test" and to some extend the ATSM 2197-15 19 has been impactful for manufacturers despite the existence of other US-driven tests, that nevertheless presented a number of negative issues for testing formulated wipes.…”

Section: Introductionmentioning

confidence: 99%

Impact of test protocols and material binding on the efficacy of antimicrobial wipes

Wesgate

Robertson

Barrell

et al. 2019

Journal of Hospital Infection

View full text Add to dashboard Cite

Background: The use of effective cleaning/disinfectant product is important to control pathogens on healthcare surfaces. With the increasing number of wipe products available, there is a concern that combination of a formulation with the wrong material will decrease the product efficacy. This study aims to use a range of efficacy test protocols to determine the efficacy of four formulations before and after binding to three commonly used wiping materials. Method: Two quaternary ammonium and one hydrogen peroxide-based products, and one neutral cleaner, were combined with microfiber, cotton or non-woven materials and tested for efficacy against Pseudomonas aeruginosa and Staphylococcus aureus with two surface tests (ASTM E2197-17; EN13697-15) and two "product" tests (ASTM E2967-15 and EN16615-15). Findings: Overall the impact of using different materials on formulation efficacy was limited, except for an alkyl(C12-16)dimethylbenzylammonium chloride-based product used at 0.5% v/v. The hydrogen peroxide product was the most efficacious regardless of the material used. The results from the wipe-test ASTM E2967-15 were consistent with those from the surface tests but not with the EN16615-15 which was far less stringent. Conclusions: The use of different wiping cloth materials might not impact severely on the efficacy of potent disinfectants despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be more at risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label.

show abstract

Section: Introductionmentioning

confidence: 99%

Impact of test protocols and material binding on the efficacy of antimicrobial wipes

Wesgate

Robertson

Barrell

et al. 2019

Journal of Hospital Infection

View full text Add to dashboard Cite

show abstract

“…However, studies have showed that the selection of an inappropriate textile material could bind with the absorbed active ingredient resulting in reduced or totally inhibited antimicrobial efficacy. [23][24][25][26] Textilebased materials in contact with an aqueous QACs solution are subjected to 2 main process: i) the absorption of the solution onto the textile material due to its absorbency characteristic, one of the most important physical properties of textile materials, and ii) the adsorption of active ingredients from the solution onto textile material, which can result from the adhesion of the molecule or chemical interaction. 27 Adsorption is intended as the accumulation of a substance (active ingredient) at the interface between a solid surface (textile) and the bathing solution (disinfectant).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Efficiency and Surface Interactions of Quaternary Ammonium Compound Absorbed on Dielectric Barrier Discharge (DBD) Plasma Treated Fiber-Based Wiping Materials

Song

Cvelbar

Stražar

et al. 2019

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…Whilst a mixture of agents may possess antimicrobial efficacy in a solution, there are many factors that can affect the efficacy of a formulation, especially when it is applied to a fabric or required for use over long time periods, as is the case with wet wipes [13]. Once applied to a fabric wipe and stored in a tub, the properties of a solution can change.…”

Section: Introductionmentioning

confidence: 99%

“…Once applied to a fabric wipe and stored in a tub, the properties of a solution can change. The active ingredients may adhere irreversibly to the fabric of the wipe through adsorption, hindering release and potentially eliminating all previously observed efficacy [13]. Furthermore, once a sealed tub has been opened, desiccation can occur, which along with chemical degradation, can result in diminishing activity over time.…”

Section: Introductionmentioning

confidence: 99%

Digluconate and Isopropyl Alcohol Biocide Formulation

Hendry

Conway

Worthington

2012

IJMS

View full text Add to dashboard Cite

Effective surface disinfection is a fundamental infection control strategy within healthcare. This study assessed the antimicrobial efficacy of novel biocide formulations comprising 5% and 2% eucalyptus oil (EO) combined with 2% chlorhexidine digluconate (CHG) and 70% isopropyl alcohol (IPA) contained within a wipe. The efficacy of this novel antimicrobial formulation to remove and eliminate methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Candida albicans from steel surfaces was investigated. Adpression studies of pre-contaminated wipes were also utilised to assess their potential to induce cross-contamination between hard surfaces. Furthermore, the bactericidal nature of the EO-formulation was established in addition to time-kill. The EO-containing formulations demonstrated bactericidal antimicrobial efficacy against all microorganisms and did not induce surface cross-contamination. There was no significant difference (p < 0.05) between the 5% and 2% EO formulations in their ability to remove microorganisms from steel surfaces, however both significantly (p < 0.05) removed more than the control formulations. Microbial biofilms were eliminated within 10 min (p < 0.05) when exposed to the EO formulations. Our novel EO-formulation demonstrated rapid antimicrobial efficacy for potential disinfection and elimination of microbial biofilms from hard surfaces and may therefore be a useful adjunct to current infection control strategies currently employed within healthcare facilities.

show abstract

Adsorption of active ingredients of surface disinfectants depends on the type of fabric used for surface treatment

Cited by 26 publications

References 19 publications

Impact of test protocols and material binding on the efficacy of antimicrobial wipes

Impact of test protocols and material binding on the efficacy of antimicrobial wipes

Antimicrobial Efficiency and Surface Interactions of Quaternary Ammonium Compound Absorbed on Dielectric Barrier Discharge (DBD) Plasma Treated Fiber-Based Wiping Materials

Digluconate and Isopropyl Alcohol Biocide Formulation

Contact Info

Product

Resources

About