Adsorption performance and mechanism of mycotoxin on montmorillonite modified by organosilicon grafting

Lv, Mengxia; Mao, Jiaqi; Zhou, Ying; Zhou, Renxian; Zhang, Jianmin

doi:10.1016/j.arabjc.2021.103314

Cited by 9 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The concentration selection was also based off of the cell viability results from our previously published study [ 41 ]. The entire reaction for each sample was performed under constant agitation on a temperature-controlled orbital shaker maintained at 39 °C at 100 rpm for 2 h. After incubation, the pH was neutralized to 7 with NaOH (0.5 and 1M) to simulate intestinal digestion, and the samples were then further incubated for an additional 2 h under the same stirring and temperature conditions [ 18 , 24 , 70 ].…”

Section: Methodsmentioning

confidence: 99%

Comparative Assessment of Different Yeast Cell Wall-Based Mycotoxin Adsorbents Using a Model- and Bioassay-Based In Vitro Approach

Yiannikouris

Shandilya

et al. 2023

Toxins

View full text Add to dashboard Cite

Frequently reported occurrences of deoxynivalenol (DON), beauvericin (BEA), and, to a lesser extent, ochratoxin A (OTA) and citrinin (CIT) in ruminant feed or feedstuff could represent a significant concern regarding feed safety, animal health, and productivity. Inclusion of yeast cell wall-based mycotoxin adsorbents in animal feeds has been a common strategy to mitigate adverse effects of mycotoxins. In the present study, an in vitro approach combining adsorption isotherm models and bioassays was designed to assess the efficacy of yeast cell wall (YCW), yeast cell wall extract (YCWE), and a postbiotic yeast cell wall-based blend (PYCW) products at the inclusion rate of 0.5% (w/v) (ratio of adsorbent mass to buffer solution volume). The Hill’s adsorption isotherm model was found to best describe the adsorption processes of DON, BEA, and CIT. Calculated binding potential for YCW and YCWE using the Hill’s model exhibited the same ranking for mycotoxin adsorption, indicating that BEA had the highest adsorption rate, followed by DON and CIT, which was the least adsorbed. PYCW had the highest binding potential for BEA compared with YCW and YCWE. In contrast, the Freundlich isotherm model presented a good fit for OTA adsorption by all adsorbents and CIT adsorption by PYCW. Results indicated that YCW was the most efficacious for sequestering OTA, whereas YCWE was the least efficacious. PYCW showed greater efficacy at adsorbing OTA than CIT. All adsorbents exhibited high adsorption efficacy for BEA, with an overall percentage average of bound mycotoxin exceeding 60%, whereas moderate efficacies for the other mycotoxins were observed (up to 37%). Differences in adsorbent efficacy of each adsorbent significantly varied according to experimental concentrations tested for each given mycotoxin (p < 0.05). The cell viability results from the bioassay using a bovine mammary epithelial cell line (MAC-T) indicated that all tested adsorbents could potentially mitigate mycotoxin-related damage to bovine mammary epithelium. Results from our studies suggested that all tested adsorbents had the capacity to adsorb selected mycotoxins in vitro, which could support their use to mitigate their effects in vivo.

show abstract

Section: Methodsmentioning

confidence: 99%

Comparative Assessment of Different Yeast Cell Wall-Based Mycotoxin Adsorbents Using a Model- and Bioassay-Based In Vitro Approach

Yiannikouris

Shandilya

et al. 2023

Toxins

View full text Add to dashboard Cite

show abstract

“…Aluminosilicates, which include bentonite, zeolite, sepiolite and montmorillonite, are the most commonly used sorbents for the control of mycotoxins in animal feed. Activated carbon is a sorbent formed from charcoal and used equally often for this purpose ( 10 , 19 , 25 ). A disadvantage of these sorbents is that they act selectively against one or two mycotoxins ( 9 ).…”

Section: Introductionmentioning

confidence: 99%

The efficiency of mycotoxin binding by sorbents in the in vitro model using a naturally contaminated animal feed

Żybura,

Jedziniak

2024

Journal of Veterinary Research

View full text Add to dashboard Cite

Introduction The productivity of domestic animals and the safety of food products derived from them are jeopardised by mycotoxins in animal feed. To control them, feed additives are used, which limit the absorption of mycotoxins in the gastrointestinal tract of animals by binding to them. The study aimed to evaluate the effectiveness of a new in vitro model in experiments on the binding of mycotoxins from buffers and contaminated feed and to confirm the effect of a single sorbent or mixture in binding them. Material and Methods Nine mineral sorbents were tested for their efficiency binding eight mycotoxins. Two in vitro experiments were conducted to indicate the mycotoxin-binding capacity of sorbents, each specifying a buffer with one of two different pH levels reflecting gastrointestinal conditions (pH 3.5 and 7.0). The first investigated the sorbent with only the buffer and mycotoxin standards, while the second did so with the sorbent, buffer and feed naturally contaminated with mycotoxins (deoxynivalenol, zearalenone, and ochratoxin A). Results The sorption was significantly lower in the trial with feed. In the first experiment at gastric pH (pH 3.5), activated charcoal bound deoxynivalenol and sepiolite bound zearalenone at 70% and 96%, respectively, whereas in the second experiment with feed, the binding was only 3% and 6%. Conclusion The study underlines the challenge of finding a feed additive that would work comprehensively, binding all mycotoxins regulated by law.

show abstract

“…24 Some of the sorbents studied include bentonites, zeolites, aluminosilicates, modied montmorillonites, and carbonaceous, magnetic, chitosan-based, and polymeric nanomaterials, to mention a few. 21,[25][26][27][28][29][30] Although some of them are effective for OTA removal, different factors such as lack of selectivity and stability, high cost, and technical complexity represent some of the limitations for their application. 26 This work aimed to synthesize a Zn-Al layered double hydroxide and evaluate its capability to retain mycotoxins, particularly ochratoxin A.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and evaluation of a Zn–Al layered double hydroxide for the removal of ochratoxin A. Greenness assessment

et al. 2022

View full text Add to dashboard Cite

show abstract

Adsorption performance and mechanism of mycotoxin on montmorillonite modified by organosilicon grafting

Cited by 9 publications

References 11 publications

Comparative Assessment of Different Yeast Cell Wall-Based Mycotoxin Adsorbents Using a Model- and Bioassay-Based In Vitro Approach

Comparative Assessment of Different Yeast Cell Wall-Based Mycotoxin Adsorbents Using a Model- and Bioassay-Based In Vitro Approach

The efficiency of mycotoxin binding by sorbents in the in vitro model using a naturally contaminated animal feed

Synthesis and evaluation of a Zn–Al layered double hydroxide for the removal of ochratoxin A. Greenness assessment

Contact Info

Product

Resources

About