Adsorption properties of zeolites for artificial kidney applications

Wernert, Véronique; Schäf, O.; Ghobarkar, H.; Denoyel, Renaud

doi:10.1016/j.micromeso.2005.03.018

Cited by 129 publications

(77 citation statements)

References 12 publications

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“…The large pores observed in the zeolite framework made easy the leisurely release of materials so that it can be accepted for medicine delivery implementation [42]. Rodriguez-Fuentes et al [43] used natural crystals of natural clinoptilolites that were purified as anti-diarrheic drugs, and the same zeolite was applied by Wernert et al [44] for outer wound treatment and withdrawal of ionic ammonia from dialyzed kidneys. Vzygula et al [45] have used natural zeolite for animal diet use in order to make better the eggs quality, and the zeolite application for medicine adsorption to neutralize the injurious effect of toxic swallow ingredients has been done by Kececi et al [46].…”

Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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Abstract. This review focuses on the latest reports of the use of zeolites, natural as well as synthetic, as biomedical materials. Discussion on biocompatibility, non-toxicity, zeolite for drug delivery materials, zeolite for bone implants and implant coatings, and the mechanical properties of polymer-zeolite composites are included. The section on the interaction between body tissues and zeolite-based biomaterials focuses on their biocompatibility, non-toxicity, and bioactivity. The next section concerns drug delivering biomaterials. Including delivery of a controlled drug, ionic removal, and synthesized drug delivering materials. The final section concern bone graft substitutes and implant-coating to improve corrosion resistance and osteointegration. The implant material system discussed in a further section is an investigation of the mechanical properties of high-density polyethylene(HDPE)-zeolite composites developed as skull bone implant materials.

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Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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“…Several materials were investigated for the adsorption of uremic toxins. In vitro experiments have shown that some materials like activated charcoal (Lee and Hsu, 1990), hydrous alumino-silicates such as the phyllosilicates clays, zeolite (Wernert et al, 2005), and sepiolite (Grynpas et al, 1984) could be used as adsorbers of uremic toxins. Wernert et al (2005) mentioned the use of activated carbon as adsorbent for different uremic toxins.…”

Section: Introductionmentioning

confidence: 99%

“…In vitro experiments have shown that some materials like activated charcoal (Lee and Hsu, 1990), hydrous alumino-silicates such as the phyllosilicates clays, zeolite (Wernert et al, 2005), and sepiolite (Grynpas et al, 1984) could be used as adsorbers of uremic toxins. Wernert et al (2005) mentioned the use of activated carbon as adsorbent for different uremic toxins. Activated carbon is characterized by its highly developed porosity, large surface area, variable characteristics of surface chemistry, and high degree of surface reactivity (Koubaissy et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Adsorption of uremic toxins over dealuminated zeolites

Koubaissy

Toufaily

Yaseen

et al. 2016

Adsorption Science & Technology

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In this study, adsorption capacities of uremic toxins over Faujasite (HFAU) and Beta (HBEA) have been evaluated by varying the composition of solvent by using water, physiological, and sodium chloride solutions. HFAU was found to be more efficient in adsorption of these molecules. The adsorption results over HFAU were compared in various conditions to understand the adsorption mechanism. Thus, the adsorption mechanism was confirmed also by Fourier transform infrared and X-ray diffraction analysis, and it is found to be through the interaction of creatinine by hydrogen bonding on two types of sites on zeolites. Pseudo-second-order equation described well the adsorption kinetics data. Equilibrium isotherms were determined by Fowler-Guggenheim model. Finally, hydrophobic HFAU zeolite seems to be an efficient adsorbent; it is able to be easily regenerated under air, through retention of these initial adsorption properties.

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“…The average concentration of urea and creatinine in patients are 38,333 6 18,333 and 1204 6 407 mmol, while that of normal health persons are less than 6700 and 106 mmol, respectively. 7 Uremic toxins can also be eliminated by adsorption other than the traditional diffusion mechanism which are used in dialyzers nowadays. In previous research, [8][9][10][11] zeolites powders are used to adsorb uremic toxins.…”

Section: Introductionmentioning

confidence: 99%

Creatinine adsorption capacity of electrospun polyacrylonitrile (PAN)‐zeolite nanofiber membranes for potential artificial kidney applications

Samarasekera

Yeow

2015

J of Applied Polymer Sci

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Innovative dialysis membranes are needed for dialysis, which is the primary treatment for patients with end stage renal disease. In this study, we developed a polyacrylonitrile zeolite nanofiber composite membrane using an electrospinning process to adsorb uremic toxins through molecular sieve mechanism. Scanning electron microscope images revealed that the average diameter of the fiber fabricated with 10 wt % polyacrylonitrile was 673 nm and that of polyacrilonitirle-zeolite membranes were 2772419 nm. The creatinine adsorption behavior of 500-KOA (L), 720-KOA (Farrierite), 840-NHA (ZSM-5), and 940-HOA (Beta) zeolite powders were investigated. Among all the zeolites, 940-HOA zeolites showed the best performance. The creatinine adsorption capacity of 940-zeolite powders increased from 2234 mg/g in 50 mmol/L creatinine solution to 25423 mg/g in 625 mmol/L creatinine solution. The speed of adsorption was very quick; 0.025 g of 940-zeolite powders can eliminate 91% of 2 mmol creatinine in 5 min. The zeolites incorporated inside the membrane had higher creatinine adsorption capacity than free zeolites.

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Adsorption properties of zeolites for artificial kidney applications

Cited by 129 publications

References 12 publications

Zeolite-based biomaterials for biomedical application: A review

Zeolite-based biomaterials for biomedical application: A review

Adsorption of uremic toxins over dealuminated zeolites

Creatinine adsorption capacity of electrospun polyacrylonitrile (PAN)‐zeolite nanofiber membranes for potential artificial kidney applications

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