Adult embryonal rhabdomyosarcoma in the nasal cavity; a case report with a review of the literature

Fatah, Mariwan L.; Salh, Abdulwahid M.; Abdullah, Ari M.; Kakamad, Fahmi H.; Mustafa, Suzana; Kakamad, Suhaib H.

doi:10.1016/j.amsu.2022.103424

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Nasal acinar rhabdomyosarcoma, one of the histopathological types of rhabdomyosarcoma, has rapid disease progression and high mortality. Therefore, the treatment of rhabdomyosarcoma requires a combination of surgery, chemotherapy, radiotherapy and immunotherapy to work together to achieve the best care for the patients [3] . Surgical resection is usually the first step in managing rhabdomyosarcoma, followed by chemotherapy and/or other treatment modalities decided on a case-by-case basis.…”

Section: Discussionmentioning

confidence: 99%

Rhabdomyosarcoma of the nasal cavity: a case report

Huang

Deng

2023

European Journal of Case Reports in Internal Medicine

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Introduction: Rhabdomyosarcoma is a high-grade malignant neoplasm with skeletal muscle differentiation; a common soft tissue sarcoma in children but considered one of the rarest in adults. Case description: We report a case of 35-year-old male with a chronic productive cough and haemoptysis for five days. A CT scan of the nasopharynx revealed a blocked left maxillary and ethmoid sinus with bone destruction. These findings raised a suspicion of a tumour, and trans-nasal endoscopic sinus surgery was performed. Discussion: Nasal rhabdomyosarcoma is a rare adult malignant tumour. Most patients have lymphatic metastasis or skull base tumour infiltration at the time of the initial diagnosis and treatment, which poses a challenge to the diagnosis and management. Conclusion: Nasal acinar rhabdomyosarcoma, one of the histopathological types of rhabdomyosarcoma, has rapid disease progression and high mortality. Therefore, the treatment of rhabdomyosarcoma requires a combination of surgery, chemotherapy, radiotherapy, and immunotherapy to work together to achieve the best care for the patient.

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Section: Discussionmentioning

confidence: 99%

Rhabdomyosarcoma of the nasal cavity: a case report

Huang

Deng

2023

European Journal of Case Reports in Internal Medicine

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Uncommon Nasal Mass Presentation: A Radiological Case Series

Casto,

Lorusso,

Palizzolo

et al. 2024

JPM

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Background: Nasal and paranasal sinus masses can arise from a wide range of conditions, both benign and malignant, as well as congenital or acquired. Diagnosing these masses is often challenging, requiring a combination of nasal endoscopy, imaging studies, and histopathological analysis. Initial imaging frequently involves computed tomography or cone beam computed tomography (CBCT) to evaluate the bony anatomy of the nasal cavity and surrounding sinuses, while magnetic resonance imaging (MRI) is typically used for detailed assessment of soft tissues and to aid in differential diagnosis when the findings are inconclusive. Methods: This review examines nasal masses evaluated using CT, CBCT, and MRI, highlighting key imaging features that may assist in differential diagnosis. Results: For non-neoplastic lesions, examples include conditions such as rhinoliths, inverted mesiodens, and septal mucoceles. Benign and borderline tumors discussed encompass lobular capillary hemangioma, inverted papilloma, septal osteoma, chondromesenchymal hamartoma, hemangioma, hemangiopericytoma, antrochoanal polyp, sinonasal angiofibroma, ossifying fibroma, and lipoma. Malignant tumors addressed in this review include adenocarcinoma, esthesioneuroblastoma, non-Hodgkin lymphoma, melanoma, and sarcoma. Conclusions: Diagnosing nasal lesions represent a significant challenge for otolaryngologists. Imaging characteristics of nasal masses play a crucial role in narrowing down differential diagnoses before surgery. However, nasal endoscopy combined with biopsy remains the definitive diagnostic approach.

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Adult embryonal rhabdomyosarcoma in the nasal cavity; a case report with a review of the literature

Cited by 2 publications

References 17 publications

Rhabdomyosarcoma of the nasal cavity: a case report

Rhabdomyosarcoma of the nasal cavity: a case report

Uncommon Nasal Mass Presentation: A Radiological Case Series

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