Adult gonococcal keratoconjunctivitis with AIDS.

Lau, Richard; Goh, B T; Estreich, S.; Cox, Sarah N; Levy, Itzchak

doi:10.1136/bjo.74.1.52

Cited by 14 publications

(3 citation statements)

References 3 publications

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“…They cause membranous or pseudomembranous conjunctivitis with ulceration, scarring and perforation as the organism can penetrate the normal corneal epithelium. HIV infection can modify the typical host response to gonococci , resulting in more severe ocular signs and symptoms 60. Gram staining and culture helps in the identification of the etiological agent.…”

Section: Anterior Segment Lesions Due To Hiv Diseasementioning

confidence: 99%

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

Biswas¹,

Sudharshan²

2008

Indian J Ophthalmol

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Ocular complications are known to occur as a result of human immunodeficiency virus (HIV) disease. They can be severe leading to ocular morbidity and visual handicap. Cytomegalovirus (CMV) retinitis is the commonest ocular opportunistic infection seen in acquired immune deficiency syndrome (AIDS). Though posterior segment lesions can be more vision-threatening, there are varied anterior segment manifestations which can also lead to ocular morbidity and more so can affect the quality of life of a HIV-positive person. Effective antiretroviral therapy and improved prophylaxis and treatment of opportunistic infections have led to an increase in the survival of an individual afflicted with AIDS. This in turn has led to an increase in the prevalence of anterior segment and adnexal disorders. Common lesions include relatively benign conditions such as blepharitis and dry eye, to infections such as herpes zoster ophthalmicus and molluscum contagiosum and malignancies such as squamous cell carcinoma and Kaposi′s sarcoma. With the advent of highly active antiretroviral therapy, a new phenomenon known as immune recovery uveitis which presents with increased inflammation, has been noted to be on the rise. Several drugs used in the management of AIDS such as nevirapine or indinavir can themselves lead to severe inflammation in the anterior segment and adnexa of the eye. This article is a comprehensive update of the important anterior segment and adnexal manifestations in HIV-positive patients with special reference to their prevalence in the Indian population.

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Section: Anterior Segment Lesions Due To Hiv Diseasementioning

confidence: 99%

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

Biswas¹,

Sudharshan²

2008

Indian J Ophthalmol

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“…Small series even reported the use of intravitreal triamcinolone ( 67 ). One study assessed the RD rate if CS were given before the diagnosis of ARN and it did not show an increased rate ( 68 ). Due to small numbers however, these results should be treated with caution.…”

Section: Treatmentmentioning

confidence: 99%

Acute retinal necrosis: A mini review

Hoogewoud¹,

Rossi²,

Stappler³

et al. 2022

Front. Ophthalmol.

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Acute retinal necrosis is a rare but potentially devastating disease. Even in the era of modern medicine, retinal detachment is a frequent complication leading to vison loss, as well as phthisis bulbi. Whereas IV acyclovir still remains the standard of care, high doses of valacyclovir with/without additional intravitreal injections of foscarnet have been used. In an attempt to reduce the retinal detachment rate, prophylactic laser treatment and early vitrectomy have been proposed. In this article, we aim to review current diagnostic and treatment modalities.

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“…Emiatt minden gonorrhoeás conjunctivitisszel diagnosztizált beteget sürgősségi esetként kell kezelni és azonnali, a szakmai irányelveknek megfelelő parenteralis terápiában részesíteni. Nem megfelelő terápia esetén már 24 órán belül kialakulhat a cornea perforációja [12,13]. Ezért kiemelkedően fontos a gonorrhoeás és chlamydiás urethritisszel diagnosztizált betegek gondos vizsgálata és követése.…”

Section: Megbeszélésunclassified

Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia trachomatis coinfection

et al. 2013

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A keratoconjunctivitis gonorrhoica ritka, a Neisseria gonorrhoeae által okozott gennyes váladékozással kísért kötő-hártya-gyulladás, amelyet felnőtteknél a szembe kerülő fertőző váladék okozhat. A Chlamydia trachomatis D-K szerotípusa által okozott conjunctivitis felnőttkori formáját nemi váladékok szembe kerülésével létrejött, kétoldali mucopurulens váladékozással kísért gyulladás jellemzi. A szerzők egy 33 éves, syphilis latens tarda miatt gondozott férfi beteg esetét ismertetik, akinek a hetek óta fennálló purulens conjunctivitise hátterében a mikrobiológiai vizsgálatok során Chlamydia trachomatis-fertőzéssel kombinált Neisseria gonorrhoeae-infekció igazolódott. A tenyész-téses és PCR-vizsgálatok során a pharynxból is kimutatható volt mindkét kórokozó. A betegnek sem urológiai, sem felső légúti tünetei nem voltak. A fertőződés kábítószer hatása alatt történt szexuális abúzust követően alakult ki. A parenteralis, majd per os cephalosporin-és azithromycinterápia hatására három hét alatt teljes remisszió követ-kezett be. Orv. Hetil., 2013, 154, 834-837. Kulcsszavak: Neisseria gonorrhoeae, Chlamydia trachomatis D-K, conjunctivitis, ceftriaxon, azithromycin Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia trachomatis coinfectionGonococcal conjunctivitis is a rare infection induced by Neisseria gonorrhoeae and it usually manifests as a hyperacute purulent conjunctivitis. Ocular access of the infectious secretion during sexual intercourse is the way of transmission among adults. Inclusion conjunctivitis caused by the serovars D-K of Chlamydia trachomatis also affects the sexually active population. Authors present a case of a 33-year-old homosexual man who was treated for late latent syphilis formerly. Clinical symptoms were yellow purulent discharge for 3 weeks without any urological or upper respiratory tract symptoms. Conjunctival Neisseria gonorrhoeae and Chlamydia trachomatis infection was identifi ed using cultures and polymerase chain reaction; pharyngeal swab culture and polymerase chain reaction showed positive results for both pathogens. The patient was probably under infl uence of party drugs at the time of sexual abuse when he became infected. After parenteral and oral cephalosporin and azithomycin therapy the patient had complete recovery within three weeks. Orv. Hetil., 2013, 154, 834-837. A Neisseria gonorrhoeae által okozott infekciók az esetek döntő részében az urogenitalis traktust érintik, az extragenitalis forma (proctitis, pharyngitis, conjunctivitis) előfordulása ritkább. Magyarországon 2011-ben a regisztrált N. gonorrhoeae-infekciók száma 1369 volt, ebből pharyngealis gonorrhoeafertőzést 37 esetben regisztráltak, amely adatok az ezt megelőző évekhez ké-pest 15-25%-os emelkedést jelentenek [1]. Az ophthalmoblenorrhoea adultorum ritka, hazai közlésről nincs tudomásunk. Németországi adatok alapján az összes gonorrhoeás fertőzés mintegy 0,19%-át teszi ki [2]. Az infekció gyors lefolyású, a fertőződéstől számított kettő-

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Adult gonococcal keratoconjunctivitis with AIDS.

Abstract: Gonococcal eye infection in adults is an

Cited by 14 publications

References 3 publications

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

Acute retinal necrosis: A mini review

Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia trachomatis coinfection

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