Adult Ovarian Retinoblastoma Genomic Profile Distinct From Prior Childhood Eye Tumor

Soh, Shui Yen; Dimaras, Helen; Gupta, Abha; Rushlow, Diane; Swallow, Carol J.; Crump, Michael; Halliday, William; Doyle, John; Babyn, Paul; Hèon, Elise; Gallie, Brenda L.; Chan, Helen S. L.

doi:10.1001/archophthalmol.2011.220

Search citation statements

Order By: Relevance

Paper Sections

Select...

Independent Second Non-ocular Retinoblastoma1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2011

2016

Publication Types

Select...

Book2

Article1

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Soh et al (Soh et al, 2011) reported a case of an independent retinoblastoma located in the ovary of a bilateral ophthalmic retinoblastoma survivor. Eighteen years after radiation of the right eye and enucleation of the left eye, the patient was found to have a large left ovarian tumor involving the fallopian tube, mesentery, and lymph nodes.…”

Section: Independent Second Non-ocular Retinoblastomamentioning

confidence: 99%

Second Malignancies in Retinoblastoma: The Real Problem

Williams¹,

Schefler²

2012

Retinoblastoma: An Update on Clinical, Genetic Counseling, Epidemiology and Molecular Tumor Biology

View full text Add to dashboard Cite

Section: Independent Second Non-ocular Retinoblastomamentioning

confidence: 99%

Second Malignancies in Retinoblastoma: The Real Problem

Williams¹,

Schefler²

2012

Retinoblastoma: An Update on Clinical, Genetic Counseling, Epidemiology and Molecular Tumor Biology

View full text Add to dashboard Cite

Adult Ovarian Retinoblastoma Genomic ProfileAdult Ovarian Retinoblastoma

Levin

O’Brien²

2011

JAMA

View full text Add to dashboard Cite

Pediatric Cancers and Brain Tumors in Adolescents and Young Adults

McCabe¹,

Valteau‐Couanet

2016

Progress in Tumor Research

View full text Add to dashboard Cite

Embryonal tumors classically occur in young children, some principally within the first year of life. Prospective national and international clinical trials during recent decades have brought about progressive improvements in survival, and associated biological studies have advanced our understanding of tumor biology, in some cases allowing biological tumor characteristics to be harnessed for therapeutic benefit. Embryonal tumors continue to occur, albeit less commonly, during childhood, adolescence and throughout adulthood. These tumors are less well understood, usually not managed according to standardized protocols and rarely included in clinical trials. Survival outcomes are generally poorer than their childhood equivalents. We present here a summary of the published literature on embryonal tumors that present ectopically during adolescence and adulthood. We show that for some tumors protocol-driven treatment, supported by accurate and complete diagnostics and staging, can result in equivalent outcomes to those seen during childhood. We make the case that clinical trial eligibility criteria should be disease-based rather than age-based, and support improvements in dialogue between children's and adults' cancer clinicians to improve outcomes for these rare tumors.

show abstract

Adult Ovarian Retinoblastoma Genomic Profile Distinct From Prior Childhood Eye Tumor

Cited by 3 publications

References 7 publications

Second Malignancies in Retinoblastoma: The Real Problem

Second Malignancies in Retinoblastoma: The Real Problem

Adult Ovarian Retinoblastoma Genomic ProfileAdult Ovarian Retinoblastoma

Pediatric Cancers and Brain Tumors in Adolescents and Young Adults

Contact Info

Product

Resources

About