Adult to adult living-related liver transplant: Report on an initial experience in Italy

Gruttadauria, Salvatore; Marsh, J. Wallis; Cintorino, Davide; Biondo, Domenico; Luca, Angelo; Vizzini, Giovanni; Volpes, Riccardo; Marcos, Amadeo; Gridelli, Bruno

doi:10.1016/j.dld.2007.01.006

Cited by 24 publications

(16 citation statements)

References 23 publications

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“…Surgical technique, principles, and strategies developed in the living related donor operation were adopted even for the cancer cases. Living donor safety was the first priority during the entire process of LRLT, from the first day of evaluation through the entire follow-up period; details of the preoperative work-up, surgical procedures, and follows-up have been reported elsewhere [33][34][35].…”

Section: Patient Resected For Neoplasm On Healthy Livermentioning

confidence: 99%

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Nutritional aspects in patient undergoing liver resection

et al. 2011

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In the past two decades, hepatic surgery has achieved important technical breakthroughs resulting in a drastic reduction of the onset of complications and in an improved post-resective survival. Pre-operative nutritional status is one of the key points for the success of a liver resection. Modern surgical achievement such as the development of living-related liver donation, and the possibility to perform more laparoscopic liver resection gave us the opportunity to extend post-operative protocol focused on early intestinal feeding to tumor patients. The aims of this review were to report the current status of the knowledge regarding nutritional aspects in liver resection patients.

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Section: Patient Resected For Neoplasm On Healthy Livermentioning

confidence: 99%

“…LRLT was initially performed successfully in the pediatric population [36], and then proposed as one of the most effective measures to counteract organ shortage in adults [33][34][35].…”

Section: Patient Resected For Neoplasm On Healthy Livermentioning

confidence: 99%

Nutritional aspects in patient undergoing liver resection

et al. 2011

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“…Details of surgical procedures are reported elsewhere [5,6] . Volumetric computed tomography (CT) scan was used to calculate liver and spleen volumes.…”

Section: Methodsmentioning

confidence: 99%

Early graft dysfunction following adult-to-adult living-related liver transplantation: Predictive factors and outcomes

Gruttadauria¹,

Francesco²,

Vizzini³

et al. 2009

WJG

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AIM:To describe a condition that we define as early graft dysfunction (EGD) which can be identified preoperatively. METHODS:Small-for-size graft dysfunction following living-related liver transplantation (LRLT) is characterized by EGD when the graft-to-recipient body weight ratio (GRBWR) is below 0.8%. However, patients transplanted with GRBWR above 0.8% can develop dysfunction of the graft. In 73 recipients of LRLT (GRBWR > 0.8%), we identified 10 patients who developed EGD. The main measures of outcomes analyzed were overall mortality, number of re-transplants and length of stay in days (LOS). Furthermore we analyzed other clinical pre-transplant variables, intraoperative parameters and post transplant data. RESULTS:A trend in favor of the non-EGD group (3-mo actuarial survival 98% vs 88%, P = 0.09; 3-mo graft mortality 4.7% vs 20%, P = 0.07) was observed as well as shorter LOS (13 d CONCLUSION: EGD can be identified preoperatively and is associated with increased morbidity after LRLT. A prompt recognition of EGD can trigger a timely treatment.

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“…At our institution, of 256 individuals who underwent evaluation as potential donors, only 80 qualified and donated part of their liver [1] . Donor mortality is a rare but catastrophic event which has an incidence between 0.13% (for pediatric donation) and 0.2% (for adult donation).…”

Section: Living Donor Liver Transplantation (Ldlt): Donor Selection Amentioning

confidence: 99%

“…It is also a means of overcoming the shortage of organs, and mortality on the waiting list. In a country such as Italy, with a population of 55 million and with 500 000 infants born each year, it can be estimated that the need for liver transplantation is between 1650 cases and 4400 cases per year in adults [1] . The imbalance between the need and the availability of liver grafts has been a powerful stimulus for the development of innovative surgical techniques to increase the pool of organs for transplantation.…”

Section: Introductionmentioning

confidence: 99%