Advance and Prospect of Nanoscale Chinese Medicine

Abstract

Over the past few years, nanoscale Chinese medicine has emerged as a new exciting field in which theoretical and experimental studies of structure and function of nanoscale Chinese drugs have become a focus, and the importance of quality standardization of nanoscale medicament of Chinese traditional medicine as specific drugs to the fundamental development in traditional Chinese drugs has begun to be recognized. In particular, Chinese medicine dispersion, surface potentials, envelopment ratio, loading drug amounts, in vivo metabolism dynamics, bio-distribution, drug-releasing in vitro, etc., have become a new interdisciplinary frontier in life science and Chinese traditional medicine. There is an increasing need for a more systematic study of the basic issues involved in traditional Chinese medicine and a more active participation of researchers in the application area of nanoscale traditional Chinese drugs. Some advances have been and are being made in nanoscale Chinese herbs, mineral medicine including mongolia drugs such as cinnabar, with enormous prospect in clinical disease therapy. Here we review some of the main advances in this field over the past few years, explore the application prospects, and discuss the concepts, issues, approaches, and challenges, with the aim of stimulating a broader interest in developing nanoscale Chinese medicine.

Folic Acid-conjugated Graphene Oxide loaded with Photosensitizers for Targeting Photodynamic Therapy

“…The most commonly used PSs are porphyrin-based molecules 6 . Many of them are limited because of prolonged cutaneous photosensitivity, poor water solubility and inadequate selectivity 7 , which are encountered in clinical applications of numerous traditional chemicals 8 - 10 . Therefore, numerous approaches have been proposed to incorporate PSs into various delivery carriers such as liposome, polymer nanoparticles, gold nanoparticles, quantum dots, magnetic nanoparticles, silica nanoparticles, and so on 11 - 14 , which realize high selectivity, high efficacy and low risk of adverse events.…”

Cytotoxicity Property of Nano-TiO2Sol and Nano-TiO2Powder

“…Manufactured nanoparticles (NPs) of titanium dioxide (TiO 2 ) have been widely used in many fields in the recent years [1][2][3][4][5]. During the production and application, nanoparticles will be contacted with organism inevitably.…”