Advanced Electrochemical Molecularly Imprinted Polymer as Sensor Interfaces

Branger, Catherine; Brisset, Hugues

doi:10.3390/proceedings2019015022

Cited by 4 publications

(3 citation statements)

References 4 publications

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“…Typically, monomer selection is achieved by trial and error. However, recently computer modeling studies have proven to be an excellent solution to aid in the selection of the monomer, reducing the amount of experiments and reagents [62][63][64]. Two types of interaction between template and functional monomer can be used, namely covalent and non-covalent approaches.…”

Section: Molecularly Imprinted Polymersmentioning

confidence: 99%

Electrochemical Chemically Based Sensors and Emerging Enzymatic Biosensors for Antidepressant Drug Detection: A Review

Caldevilla,

Morais,

Cruz

et al. 2023

IJMS

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Major depressive disorder is a widespread condition with antidepressants as the main pharmacological treatment. However, some patients experience concerning adverse reactions or have an inadequate response to treatment. Analytical chromatographic techniques, among other techniques, are valuable tools for investigating medication complications, including those associated with antidepressants. Nevertheless, there is a growing need to address the limitations associated with these techniques. In recent years, electrochemical (bio)sensors have garnered significant attention due to their lower cost, portability, and precision. Electrochemical (bio)sensors can be used for various applications related to depression, such as monitoring the levels of antidepressants in biological and in environmental samples. They can provide accurate and rapid results, which could facilitate personalized treatment and improve patient outcomes. This state-of-the-art literature review aims to explore the latest advancements in the electrochemical detection of antidepressants. The review focuses on two types of electrochemical sensors: Chemically modified sensors and enzyme-based biosensors. The referred papers are carefully categorized according to their respective sensor type. The review examines the differences between the two sensing methods, highlights their unique features and limitations, and provides an in-depth analysis of each sensor.

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Section: Molecularly Imprinted Polymersmentioning

confidence: 99%

Electrochemical Chemically Based Sensors and Emerging Enzymatic Biosensors for Antidepressant Drug Detection: A Review

Caldevilla,

Morais,

Cruz

et al. 2023

IJMS

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“…PPy is an organic conjugated CP, benefiting from increased mechanical stability, very good electrical properties and low toxicity [40]. The electrochemical synthesis of PPy is facile and can be performed at neutral pH [41], on many different substrates, making PPy an intensively studied CP.…”

Section: Carbon-based Nanomaterials For No 2 Sensingmentioning

confidence: 99%

Recent Progress on Nanomaterials for NO2 Surface Acoustic Wave Sensors

2022

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NO2 gas surface acoustic wave (SAW)sensors are under continuous development due to their high sensitivity, reliability, low cost and room temperature operation. Their integration ability with different receptor nanomaterials assures a boost in the performance of the sensors. Among the most exploited nano-materials for sensitive detection of NO2 gas molecules are carbon-based nanomaterials, metal oxide semiconductors, quantum dots, and conducting polymers. All these nanomaterials aim to create pores for NO2 gas adsorption or to enlarge the specific surface area with ultra-small nanoparticles that increase the active sites where NO2 gas molecules can diffuse. This review provides a general overview of NO2 gas SAW sensors, with a focus on the different sensors’ configurations and their fabrication technology, on the nanomaterials used as sensitive NO2 layers and on the test methods for gas detection. The synthesis methods of sensing nanomaterials, their functionalization techniques, the mechanism of interaction between NO2 molecules and the sensing nanomaterials are presented and discussed.

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“…The major disadvantage of bulk polymerization is the bad accessibility and inhomogeneity of the binding pockets, which leads to a longer template removal time and slow rebinding. To overcome these problems, different forms of MIPs, such as micro-or nanobeads, nanoparticles or nanospheres have been prepared [16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

How Reliable Is the Electrochemical Readout of MIP Sensors?

Yarman

Scheller

2020

Sensors

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Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by their modulating effect on the diffusional permeability of a redox marker through thin MIP films. However, this process generates an overall signal, which may include nonspecific interactions with the nonimprinted surface and adsorption at the electrode surface in addition to (specific) binding to the cavities. Redox-active low-molecular-weight targets and metalloproteins enable a more specific direct quantification of their binding to MIPs by measuring the faradaic current. The in situ characterization of enzymes, MIP-based mimics of redox enzymes or enzyme-labeled targets, is based on the indication of an electroactive product. This approach allows the determination of both the activity of the bio(mimetic) catalyst and of the substrate concentration.

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Advanced Electrochemical Molecularly Imprinted Polymer as Sensor Interfaces

Cited by 4 publications

References 4 publications

Electrochemical Chemically Based Sensors and Emerging Enzymatic Biosensors for Antidepressant Drug Detection: A Review

Electrochemical Chemically Based Sensors and Emerging Enzymatic Biosensors for Antidepressant Drug Detection: A Review

Recent Progress on Nanomaterials for NO2 Surface Acoustic Wave Sensors

How Reliable Is the Electrochemical Readout of MIP Sensors?

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