Advanced Lipidomics in the Modern Meat Industry: Quality Traceability, Processing Requirement, and Health Concerns

Abstract

Over the latest decade, lipidomics has been extensively developed to give robust strength to the qualitative and quantitative information of lipid molecules derived from physiological animal tissues and edible muscle foods. The main lipidomics analytical platforms include mass spectrometry (MS) and nuclear magnetic resonance (NMR), where MS-based approaches [e.g., “shotgun lipidomics,” ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF-MS)] have been widely used due to their good sensitivity, high availability, and accuracy in identification/quantification of basal lipid profiles in complex biological point of view. However, each method has limitations for lipid-species [e.g., fatty acids, triglycerides (TGs), and phospholipids (PLs)] analysis, and necessitating the extension of effective chemometric-resolved modeling and novel bioinformatic strategies toward molecular insights into alterations in the metabolic pathway. This review summarized the latest research advances regarding the application of advanced lipidomics in muscle origin and meat processing. We concisely highlighted and presented how the biosynthesis and decomposition of muscle-derived lipid molecules can be tailored by intrinsic characteristics during meat production (i.e., muscle type, breed, feeding, and freshness). Meanwhile, the consequences of some crucial hurdle techniques from both thermal/non-thermal perspectives were also discussed, as well as the role of salting/fermentation behaviors in postmortem lipid biotransformation. Finally, we proposed the inter-relationship between potential/putative lipid biomarkers in representative physiological muscles and processed meats, their metabolism accessibility, general nutritional uptake, and potency on human health.

A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids

“…There are also forensic studies available [ 42 ] where the age of a fingerprint (in particular, the lipids within a fingerprint) can be determined by the O 3 -induced oxidation of TAG subsequent to ozonolysis [ 43 ]. The considerable relevance of MS-based lipidomics, including MALDI-TOF MS approaches in the meat industry, has been recently emphasized and comprehensively reviewed [ 44 ]. Recently, there have been strong efforts to obtain energy and fuel from algae (“renewable primary products”).…”

Integration of hepatic lipidomics and transcriptomics reveals the effect of butter-derived ruminant trans fatty acids on lipid metabolism in C57BL/6J mice

“…15 Lipidomics is a branch of metabolomics in which multiple techniques are used to quantify hundreds of chemically distinct lipids and identify potential lipid biomarkers at the molecular level. [16][17][18] By using lipidomics, Sarnyai et al suggested that EA and TVA induced a stress response and cell damage in HepG2 cells by increasing the levels of ceramide (Cer) and diglyceride (DG), and this further supported the role of DG and Cer accumulation in metabolic diseases. 3 Hepatic steatosis, non-alcoholic steatohepatitis (NASH) and liver fibrosis are the three stages of increasing severity in NAFLD, which can even deteriorate toward cirrhosis and hepatocellular carcinoma.…”

Untargeted UHPLC-TOF/MS Lipidomic Analysis for the Investigation of Egg Yolks after Xylanase Supplementation of the Diet of Laying Hens

“…Lipidomic analysis has also been applied to estimate the impact of animal feeding methods on meat and egg quality [ 12 ]. Feed intervention can greatly alter the lipid content of eggs and meat, thus improving the nutritional value and health benefits of the products.…”