“…Response surface methodology (RSM), a multivariate technique which mathematically fits the experimental domain studied in the theoretical design through a response function [22], is then proposed to solve these problems [17][18][19][20][21]. The main types of RSM designs include three-level factorial design, central composite design (CCD), Box-Behnken design and D-optimal design [17][18][19]23]. As one of the RSM designs, Box-Behnken design is known as a modified central composite experimental design [17][18][19]23].…”