Advancements in the rapid and sensitive analyses of tryptophan and its metabolites, by chromatography

Palliative Effects of Daonil Supplemented with Tryptophan on Alloxan Induced Diabetic Rats

“…Serotonin (5-HT), is an important neuro transmitter with physiological activity [10]. Tryptophan has a role in physiological (nerve transmission, immune response) and pathological processes (depression, stress, sleep and appetite disorders) [11] and therefore its plasma levels are linked to changes in mood, behaviour, anxiety, sleep, fatigue and appetite suppression [12]. The vitamin niacin and a phytohormone auxin are also synthesized from tryptophan.…”

Quantification of tryptophan in plasma by high performance liquid chromatography

“…1 It has a role in physiological (nerve transmission, immune response) and pathological processes (depression, stress, and sleep and appetite disorders) 2 and therefore its plasma levels are linked to changes in mood, behavior, anxiety, sleep, fatigue and appetite suppression. 3 These characteristics have led research centers to focus their studies on the creation of methods allowing the determination and quantification of this amino acid, as well as the identification of possible relationships between plasma levels of tryptophan with diseases and metabolic disorders.…”