Advances in Chronic Kidney Disease

Abstract

Chronic kidney disease (CKD) is characterized by renal dysfunction that is present for more than 3 months; it is also associated with a number of comorbidities [1,2].[...]

Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir

“…1 CKD is characterized by the progressive loss of kidney function over time. 2 In addition, the main causes of CKD are hypertension, diabetes, chronic pyelonephritis, and glomerular diseases (glomerulosclerosis and IgA nephropathy, diabetic nephropathy and lupus nephritis). [3][4][5] Evidence has shown that patients with diabetes or hypertension should be screened on an annual basis for CKD.…”

“… 7 The stages of CKD range from mild loss of kidney function in stage 1 (eGFR > 90 mL/min/1.73 m 2 ) to complete kidney failure in stage 5 (eGFR < 15 mL/min/1.73 m 2 ). 2 , 8 Stage 5 of CKD is known as end-stage renal disease (ESRD), and patients with ESRD require dialysis or a kidney transplant to stay alive. 7 , 9 Because CKD can progress to kidney failure (also called ESRD) and even death, early diagnosis of this disease is important for timely preventive and therapeutic interventions and preventing a time-dependent decline in eGFR.…”

Risks of female genital tract related cancers (gynecological cancers) or breast cancer in women with and without chronic kidney disease

“…This is an unexpected finding, as many studies suggested that cancer risk would be increased in the CKD patients. [ 7 – 12 , 21 – 31 ] The further surprising finding was that our study showed a negative association between CKD and GC.…”

“…[ 6 – 11 ] CKD is defined as kidney damage or decreased kidney function [glomerular filtration rate (GFR) lower than 60 mL/min per 1.73 m 2 ] for 3 months or longer. [ 12 – 14 ] The prevalence and incidence of CKD is significantly increasing in decades. [ 15 – 17 ] Compared with other countries, Taiwan has a remarkably high incidence and prevalence of patients with CKD, and end-stage of renal disease (ESRD).…”

Application of instant messaging software in the follow‐up of patients using peritoneal dialysis, a randomised controlled trial

“…It has the advantages of low cost, a simple procedure and allowing patients to perform self‐assisted dialysis at home. In addition, it has good residual renal function protection and a small impact on the body's internal environment and is being used as the preferred treatment method by increasingly more patients (Parrish, ). Currently, it is estimated that more than 272,000 patients receive PD treatment worldwide, accounting for approximately 11% of the global dialysis population (Li et al., ).…”