Advances in magnetic nanoparticles for biotechnology applications

Tartaj, Pedro; Morales, M.P.; González-Carreño, T.; Veintemillas-Verdaguer, Sabino; Serna, Carlos J.

doi:10.1016/j.jmmm.2004.11.155

Cited by 255 publications

(113 citation statements)

References 55 publications

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“…An article on the versatility of spray pyrolysis by Pramod Patil [28] among other aspects tabulated publications up to early 1999 listing materials and spray pyrolysis parameters. Other reviews have been on specific materials employing spray pyrolysis as one of the wide range of methods used in producing such materials: superconductors [29], carbon nanostructres [30], ceramic nano-composites [31], diamond [32], semi-cokes [33], and semiconductors [34]. The present review chapter will restrict its discussion to ultrasonic spray (USP) technique on a wide range of materials especially from 1999 to the present and on laser spray (LP) pyrolysis.…”

Section: Fig 1 Generalised Schematic Of Chemical Vapor Deposition Symentioning

confidence: 99%

Progress in Ultrasonic Spray Pyrolysis for Condensed Matter Sciences Developed From Ultrasonic Nebulization Theories Since Michael Faraday

Mwakikunga

2013

Critical Reviews in Solid State and Materials Sciences

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Section: Fig 1 Generalised Schematic Of Chemical Vapor Deposition Symentioning

confidence: 99%

Progress in Ultrasonic Spray Pyrolysis for Condensed Matter Sciences Developed From Ultrasonic Nebulization Theories Since Michael Faraday

Mwakikunga

2013

Critical Reviews in Solid State and Materials Sciences

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“…Indeed, a half-life of 7 ± 1 minutes was reported for a monoexponential elimination profile of dextran-coated nanoparticles in rats after intravenous administration [21]. The total area under the monoexponentially decaying concentration versus time curve (AUC T ), with an initial concentration of C 0 and plasma half-life of t 1/2 can be calculated as:…”

Section: In Vitro -In Vivo Correlationmentioning

confidence: 99%

Glioma selectivity of magnetically targeted nanoparticles: A role of abnormal tumor hydrodynamics

Chertok

David

Huang

et al. 2007

Journal of Controlled Release

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Magnetic targeting is a promising strategy for achieving localized drug delivery. Application of this strategy to treat brain tumors, however, is complicated by their deep intracranial location, since magnetic field density cannot be focused at a distance from an externally applied magnet. This study intended to examine whether, with magnetic targeting, pathological alteration in brain tumor flow dynamics could be of value in discriminating the diseased site from healthy brain. To address this question, the capture of magnetic nanoparticles was first assessed in vitro using a simple flow system under theoretically estimated glioma and normal brain flow conditions. Secondly, accumulation of nanoparticles via magnetic targeting was evaluated in vivo using 9L-glioma bearing rats. In vitro results that predicted a 7.6-fold increase in nanoparticle capture at glioma-versus contralateral brainrelevant flow rates were relatively consistent with the 9.6-fold glioma selectivity of nanoparticle accumulation over the contralateral brain observed in vivo. Based on these finding, the in vitro ratio of nanoparticle capture can be viewed as a plausible indicator of in vivo glioma selectivity. Overall, it can be concluded that the decreased blood flow rate in glioma, reflecting tumor vascular abnormalities, is an important contributor to glioma-selective nanoparticle accumulation with magnetic targeting.

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“…11,13,14 Conventional chemical synthesis of Fe 3 O 4 and γ-Fe 2 O 3 powders involves the coprecipitation of a mixture of aqueous ferrous and ferric salts. 15 Previous studies have shown that some polysaccharides have the ability to interact with iron complexes, preventing the precipitation of iron hydroxide and enabling nanoparticle synthesis to occur under controlled conditions. For example, several workers have used a coprecipitation process in the presence of dextran.…”

Section: Introductionmentioning

confidence: 99%

In Situ Synthesis of Magnetite Nanoparticles in Carrageenan Gels

et al. 2007

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Magnetite nanoparticles have been successfully synthesized in the presence of carrageenan polysaccharides using an in situ coprecipitation method. Iron coordination to the sulfate groups of the polysaccharide was confirmed by FTIR. The polysaccharide type (κ, ι, or λ) and concentration have been varied and their effects on particle morphology and chemical stability of the resultant nanocomposite investigated. The presence of carrageenan induces the formation of smaller particles, compared to those formed in the absence of polymer, and their average size depends on the nature and concentration of the polysaccharide used. The chemical stability of magnetite nanoparticles toward oxidation was also seen to depend on biopolymer type with magnetite formed in ι-carrageenan showing the highest chemical stability. A general tendency toward lower stability is observed as the polysaccharide concentration is increased. It is suggested that magnetite chemical stability in the carrageenan composites is determined by a fine balance between particle size and gel strength, the latter determining oxygen diffusion rates through the medium.

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Advances in magnetic nanoparticles for biotechnology applications

Cited by 255 publications

References 55 publications

Progress in Ultrasonic Spray Pyrolysis for Condensed Matter Sciences Developed From Ultrasonic Nebulization Theories Since Michael Faraday

Progress in Ultrasonic Spray Pyrolysis for Condensed Matter Sciences Developed From Ultrasonic Nebulization Theories Since Michael Faraday

Glioma selectivity of magnetically targeted nanoparticles: A role of abnormal tumor hydrodynamics

In Situ Synthesis of Magnetite Nanoparticles in Carrageenan Gels

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