Advances in Novel Drug Delivery Strategies for Breast Cancer Therapy

Abstract

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Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer

“…Nowadays, chemotherapy is the most commonly used treatment in the therapeutic approach; however, conventional chemotherapy has shown low efficacy when the disease is not treated in early stages [2]. As a matter of fact, chemotherapy drugs are not specific and act both on tumor and normal cells, causing side effects [3].…”

Drug delivery approaches for breast cancer

“…58 The combinations of doxorubicin and cyclophosphamide utilizing non-PEGylated liposomes were used for the treatment of metastatic breast cancer. 59 Moreover, liposome-conjugated antibody that overexpresses the HER-2 has been developed and reported as delivering 22-fold more calcein to mammary epithelial cells. 60 The synergistic effects of combined drug delivery of quercetin and vincristine through liposomes were reported for treatment of ER-negative breast cancer.…”

Biophotonic techniques for manipulation and characterization of drug delivery nanosystems in cancer therapy

“…Such nanomaterials are: lipids, polymers, protein, dendrimers, metallic or silicon nanoparticles, and quantum dots [40]. The last decades, with the rapid development of the nanotechnology, a revolutionary growth of alternative methods have been proposed using multifunctional nanosystems, which have multiple functions: early cancer detection, targeted drug delivery, and monitoring the cancer progression.…”