Advances in pain management for older patients with cancer

Hachem, Georges El; Rocha, Francisco Oliveira; Pepersack, Thierry; Jounblat, Youssef; Drowart, Annie; Lago, Lissandra Dal

doi:10.3332/ecancer.2019.980

Cited by 17 publications

(17 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Conversely, a 2019 network meta-analysis of analgesic drugs for chronic cancer pain concluded that the top-ranking drug classes for global efficacy were non-opioid analgesics, including paracetamol, as well as NSAIDs and opioids [ 126 ]. It is considered the first-choice drug for mild-to-moderate pain in older patients with cancer naïve to opioids [ 127 ].…”

Section: Clinical Guidelinesmentioning

confidence: 99%

Paracetamol: A Review of Guideline Recommendations

Freo

Ruocco

Valerio

et al. 2021

JCM

108

View full text Add to dashboard Cite

Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and pain-related disability, which are expected to rise with the rapid global population aging. Current medical treatments provide only partial relief. Furthermore, non-steroidal anti-inflammatory drugs (NSAIDs) and opioids are effective in young and otherwise healthy individuals but are often contraindicated in elderly and frail patients. As a result of its favorable safety and tolerability record, paracetamol has long been the most common drug for treating pain. Strikingly, recent reports questioned its therapeutic value and safety. This review aims to present guideline recommendations. Paracetamol has been assessed in different conditions and demonstrated therapeutic efficacy on both acute and chronic pain. It is active as a single agent and is additive or synergistic with NSAIDs and opioids, improving their efficacy and safety. However, a lack of significant efficacy and hepatic toxicity have also been reported. Fast dissolving formulations of paracetamol provide superior and more extended pain relief that is similar to intravenous paracetamol. A dose reduction is recommended in patients with liver disease or malnourished. Genotyping may improve efficacy and safety. Within the current trend toward the minimization of opioid analgesia, it is consistently included in multimodal, non-opioid, or opioid-sparing therapies. Paracetamol is being recommended by guidelines as a first or second-line drug for acute pain and chronic pain, especially for patients with limited therapeutic options and for the elderly.

show abstract

Section: Clinical Guidelinesmentioning

confidence: 99%

Paracetamol: A Review of Guideline Recommendations

Freo

Ruocco

Valerio

et al. 2021

JCM

108

View full text Add to dashboard Cite

show abstract

“…In the emergency room, assessment should start by ruling out a life-threatening medical emergency revealed by pain, cancer, or non-cancer related, followed by a quick relief of the uncontrolled cancer pain. Assessment of pain includes symptom and patient characterization, classification of etiology of pain, and identification of cancer syndrome 48,49 .…”

Section: Risk Factors and Assessment In The Ed Settingmentioning

confidence: 99%

“…Several screening tools had been implemented and until now none have been superior to the others. The Checklist of Non-verbal Pain Indicators (CNPIs) and the Pain Assessment in Advanced Dementia Scale (PAINNAD) are some screening tools that can be used in these populations 49,50 . Patient characterization must include comorbidities, on-going and past treatments, and the impact of pain on functionality, malnutrition, and psychological state.…”

Section: Risk Factors and Assessment In The Ed Settingmentioning

confidence: 99%

Geriatric emergencies in older adults with cancer: why older patients need a special approach

Torres¹,

García-Valdés²,

Henriquez-Santos³

2023

GAMO

View full text Add to dashboard Cite

The number of older adults with cancer presenting to the emergency departments for evaluation and treatment is increasing. There is an essential need to identify and better understand the effects of cancer and treatment on health outcomes for older adults with cancer. Cancer-related emergencies can manifest as geriatric syndromes in this population. Falls, delirium, and acute pain are highly prevalent, multifactorial, and associated with substantial morbidity and poor outcomes. In the present article, we review existing evidence regarding common geriatric emergencies in older adults with cancer, as well as the importance of a special approach and management in this population.

show abstract

“…The assessment of pain in elderly patients is particularly difficult because, despite the more frequent experience of pain, they report it less frequently than younger patients [27]. This is because they show greater tolerance to pain, recognizing that it is an inherent part of the ageing process, and deny its existence.…”

Section: Assessment Of Pain Intensitymentioning

confidence: 99%

Multidisciplinary management of chronic pain in elderly oncology patients

Pysz-Waberski¹,

Sadurska²,

Kędzierska-Jamróz³

et al. 2022

View full text Add to dashboard Cite

Chronic pain is one of the most common and most bothersome symptoms in cancer patients, which occurs especially often in the elderly population. Although methods of pain treatment are well known, it is not uncommon for individuals with chronic or terminal illnesses to remain underdiagnosed or untreated. Effective pain management has become the measure of success in oncology therapy. For this reason, effective pain management has become an indispensable success factor of multidisciplinary oncological therapy. Along with the growing interest in the holistic approach in medicine, and hence in interdisciplinary treatment, the management of cancer pain in older patients was presented.

show abstract

Advances in pain management for older patients with cancer

Cited by 17 publications

References 78 publications

Paracetamol: A Review of Guideline Recommendations

Paracetamol: A Review of Guideline Recommendations

Geriatric emergencies in older adults with cancer: why older patients need a special approach

Multidisciplinary management of chronic pain in elderly oncology patients

Contact Info

Product

Resources

About