Advances in the application of upconversion nanoparticles for detecting and treating cancers

Li, Kunmeng; Hong, Enlv; Wang, Bing; Wang, Zhiyu; Zhang, Liwen; Hu, Ruixia; Wang, Baiqi

doi:10.1016/j.pdpdt.2018.12.007

Cited by 62 publications

(31 citation statements)

References 128 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Upconversion nanoparticles (UCNPs) are usually selected for fluorescent labeling considering the ability to excite UCNPs with near-infrared (NIR) light to infrared (IR) light for generation of fluorescence emission in the visible region of the spectrum, leading to minimal background noise. Furthermore, applying NIR light as the excitation source prevents damage to normal tissues on one hand and allows deep tissue penetration on the other hand [68].…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

et al. 2019

View full text Add to dashboard Cite

In the fight against cancer, early detection is a key factor for successful treatment. However, the detection of cancer in the early stage has been hindered by the intrinsic limits of conventional cancer diagnostic methods. Nanotechnology provides high sensitivity, specificity, and multiplexed measurement capacity and has therefore been investigated for the detection of extracellular cancer biomarkers and cancer cells, as well as for in vivo imaging. This review summarizes the latest developments in nanotechnology applications for cancer diagnosis. In addition, the challenges in the translation of nanotechnology-based diagnostic methods into clinical applications are discussed.

show abstract

Section: Introductionmentioning

confidence: 99%

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

et al. 2019

View full text Add to dashboard Cite

show abstract

“…In recent years, the upconversion (UC) emission of rare‐earth (RE 3+ ) co‐doped in the glass/glass‐ceramics materials continues to be extensively studied by their potential applications in many fields such as biomedical imaging, three‐dimensional color display, 1,2 optical thermometry, 3 temperature sensors, 4 solar cells, 5 and biomarkers 6 . There have been many studies aiming to enhance UC emission of some typical RE 3+ ions due to their different applications.…”

Section: Introductionmentioning

confidence: 99%

Influence of Cr³⁺ on yellowish‐green UC emission and energy transfer of Er³⁺/Cr³⁺/Yb³⁺ tri‐doped zinc silicate glasses

Dan

Zhou

et al. 2020

J Am Ceram Soc

View full text Add to dashboard Cite

In this paper, we study the influence of Cr3+ on yellowish‐green upconversion (UC) emission and the energy transfer (ET) of Er3+/Cr3+/Yb3+ tri‐doped in SiO2–ZnO–Na2O–La2O3 (SZNL) zinc silicate glasses under excitation of the 980 nm laser diode (LD). The influence of Cr3+ on enhancing the red UC emission of Er3+/Cr3+/Yb3+ tri‐doped in SiO2–ZnO–Na2O–La2O3 zinc silicate glasses under the excitation of 980nm LD was also investigated. The ET processes between Yb3+, Cr3+, and Er3+, together with the combination of Yb3+‐Cr3+‐Er3+, which led to the green UC emission intensity of Er3+/Cr3+/Yb3+ tri‐doped in SiO2–ZnO–Na2O–La2O3 zinc silicate glasses bands centered at ~546 nm have been significantly enhanced. By increasing the concentration of Cr3+ from 0 up to 5 mol.%, we can locate the Commission Internationale de l'éclairage (CIE) 1931 (x; y) chromaticity coordinates for UC emissions of Er3+/Cr3+/Yb3+ tri‐doped in the central position of the yellowish‐green color region of CIE 1931 chromaticity diagram. Besides, the ET processes between the Yb3+, Cr3+, and Er3+ are also proposed and discussed.

show abstract

“…In recent years, nanomaterials have been widely used in photocatalysis [1][2][3] and electrochemical applications [4]. With recent nanotechnology developments, more and more nanomaterials find their practical as well as potential applications in biomedicine [5][6][7][8][9]. One of such example is the application of superparamagnetic Fe 3 O 4 NPs for cell targeting, drug delivery, magnetic resonance imaging, and magnetic hyperthermal cancer therapy, all of which rely on unique magnetic properties of Fe 3 O 4 as well as its biocompatibility and biodegradability [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Photothermal Effect of Superparamagnetic Fe3O4 Nanoparticles Irradiated by Near-Infrared Laser

Fu¹,

Man²,

Fu³

2020

Journal of Nanomaterials

View full text Add to dashboard Cite

Fe3O4 nanoparticles (NPs) have been widely used in biomedicine due to their unique magnetism, biocompatibility, and biodegradability. Magnetic hyperthermia of Fe3O4 NPs for cancer treatment has attracted more attention. However, it could interfere with magnetic field-sensitive devices of patients, such as pacemakers. Therefore, it is necessary to find a new method for clinical therapy. In this study, the superparamagnetic Fe3O4 NPs were fabricated. Visible-near-infrared absorption spectra indicated that the Fe3O4 NPs have near-infrared absorption. The influences of Fe3O4 NP concentrations, power density, and wavelength of near-infrared laser irradiation on the photothermal performance of Fe3O4 NPs were investigated. The results revealed that high concentrations, large power density, and short irradiation wavelength could improve the photothermal performance of Fe3O4 NPs. The temperature variation and the absorption intensity simultaneously determined the photothermal transduction efficiency of Fe3O4 NPs. The application of the photothermal performance of Fe3O4 NPs would provide a new opportunity for clinic cancer treatment.

show abstract

Advances in the application of upconversion nanoparticles for detecting and treating cancers

Cited by 62 publications

References 128 publications

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Influence of Cr³⁺ on yellowish‐green UC emission and energy transfer of Er³⁺/Cr³⁺/Yb³⁺ tri‐doped zinc silicate glasses

Photothermal Effect of Superparamagnetic Fe3O4 Nanoparticles Irradiated by Near-Infrared Laser

Contact Info

Product

Resources

About

Advances in the application of upconversion nanoparticles for detecting and treating cancers

Cited by 62 publications

References 128 publications

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Influence of Cr3+ on yellowish‐green UC emission and energy transfer of Er3+/Cr3+/Yb3+ tri‐doped zinc silicate glasses

Photothermal Effect of Superparamagnetic Fe3O4 Nanoparticles Irradiated by Near-Infrared Laser

Contact Info

Product

Resources

About

Influence of Cr³⁺ on yellowish‐green UC emission and energy transfer of Er³⁺/Cr³⁺/Yb³⁺ tri‐doped zinc silicate glasses