Advances in the Prevention of Cardiovascular Diseases by Phytosterol

Bai, Ningzhu

doi:10.1145/3340037.3340073

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Besides reducing LDL, PSO facilitated HDL synthesis and reduce arterial BP, thereby supporting overall prevention strategies. The expert panel of the American College of Cardiology and the American Heart Association Task Force, also supports LDL lowering and HDL facilitating strategies for prevention of atherosclerosis and CVD events (Bai, 2019;Barylski et al, 2014;Stone et al, 2014). Earlier, similar work has shown PSO to a worthy preventive option because of its ability to favorably benefit lipid fractions and act as an anti-hypertensive.…”

Section: Discussionmentioning

confidence: 99%

Effect of pumpkin seed oil on cholesterol fractions and systolic/diastolic blood pressure

2020

View full text Add to dashboard Cite

Pumpkin seed oil (PSO) is high in unsaturated fatty acids and plant sterols, which have numerous cardiovascular benefits. The study explores the hypothesis by investigating effects of consumption of 1000 mg of PSO on total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), systolic (SBP) and diastolic (DBP) blood pressure ((BP). PSO has high oxidative stability and contains favorable essential fatty acids profile along with sterols and tocopherols. One hundred and twenty-seven participants 39 to 63 years old, with varying degree of one or multiple medical conditions including dyslipidemia, hypertension, diabetes and obesity were randomly selected and assigned among case and control groups. Both groups were biochemically, anthropometrically and clinically assessed pre and post intervention. Group 1 (cases) (n=63) was administered 1000 mg of PSO along with recommendations for healthy diet and lifestyle whereas Group 2 (controls) (n=64), was only provided with dietary and lifestyle changes. Analysis of cases baseline and endpoint data revealed advantageous effect of intervention. Cases data showed a significant reduction in endpoint LDL and DBP values along with a likewise significant increase in HDL cholesterol. Experiment results revealed PSO possessed hypolipidemic and anti-hypertensive activity as it lowered DBP and LDL and increased HDL levels.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of pumpkin seed oil on cholesterol fractions and systolic/diastolic blood pressure

2020

View full text Add to dashboard Cite

show abstract

“…Many researches have been conducted to find the mechanism of action of plant sterols (Scolaro et al, 2020), thus it was found that difference in hydrophobicity of plant sterols prevent the cholesterol from entering into the micelles and it precipitate along with cholesterol in the intestinal lumen, hence reduces the absorption of cholesterol into the blood stream. Moreover, it also interferes with the cholesterol transport in the blood along with affecting the metabolism of cholesterol (Bai, 2019). As such no significant side effects, including gastrointestinal effects, have been observed with the consumption of plant stanol or sterol esters, only conferred a minor effect on decreasing the serum carotenoid concentration (Smet et al, 2012).…”

Section: Plant Sterol and Stanol Estersmentioning

confidence: 99%

Bioactive Functional Foods for Cardiovascular Diseases

Mustafa¹,

Ajmal²,

Naz³

et al. 2020

American Journal of Biochemistry and Biotechnology

View full text Add to dashboard Cite

Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects of CVD, epidemiology, risk factors and emphasizes the use of functional foods for the prevention and treatment of cardiovascular diseases. It highlights the importance of various foods used in daily routine and their activity against CVDs particularly. Recent studies have investigated the consumption of various foods including soybeans, oats, psyllium, flaxseed, garlic, tea, fish, grapes, nuts, fruits, vegetables, chocolate and sterol ester enhanced margarine etc., on CVD patients and their role as a natural/socioeconomic cure over chemical based drugs. Adequate intake of these foods on a constant basis, help in decreasing the risk of cardiovascular disease by several potential mechanisms e.g., lowering blood lipid levels, improving arterial compliance, reducing low-density lipoprotein oxidation, decreasing plaque formation, scavenging free radicals and inhibiting platelet aggregation etc. This review not only emphasizes the dire need of exploring safe functional foods against alarming rise of CVD cases, but also provides future insight in the use of bioactive food components in CVD therapeutics, as they are cost effective and have fewer side effects.

show abstract

Advances in the Prevention of Cardiovascular Diseases by Phytosterol

Cited by 2 publications

References 10 publications

Effect of pumpkin seed oil on cholesterol fractions and systolic/diastolic blood pressure

Effect of pumpkin seed oil on cholesterol fractions and systolic/diastolic blood pressure

Bioactive Functional Foods for Cardiovascular Diseases

Contact Info

Product

Resources

About