Adverse Cutaneous Reactions to Antimicrobials in Patients with Human Immunodeficiency Virus Infection

Abstract

Adverse reactions to medication are significant contributors to morbidity and mortality in patients with human immunodeficiency virus (HIV) infection. Cutaneous events not only constitute a significant portion of these reactions, they may also herald developing systemic reactions such as hemato-, nephro-, and hepatotoxicity. The identification of cutaneous adverse reactions and drug culprits and the proper management of reactions are of paramount importance for these patients. This review focuses specifically on adverse cutaneous reactions to antimicrobials that are commonly used in the management of patients with HIV infection.

Clinical analysis of HIV/AIDS patients with drug eruption in Yunnan, China

“…This is pertinent for the antimicrobial treatment for 78.4% of patients with bacterial co-infections26, and it also affects the adherence to antibiotic drugs in China18. Furthermore, 9.7% of patients were allergic to anti-tuberculosis drugs, of which the most common sensitizing drug was Rifamycin.…”