Adverse Effect of β-Carotene in Diet on Fertility of Dairy Cows

Folman, Y.; Ascarelli, I.; Kraus, Dagmar; Barash, H.

doi:10.3168/jds.s0022-0302(87)80017-6

Cited by 39 publications

(16 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is also observed that the higher concentrations of ß-carotene used tended to be more suppressive as compared to 1 10"7 M, suggesting possible toxic effects (see Hey wood et al, 1985). These results agree with those reported by Folman et al (1987) in which the intake of high ß-carotene seemed to have an adverse effect on fertility of dairy cows.…”

Section: Discussionsupporting

confidence: 95%

Comparative role of retinol, retinoic acid and -carotene on progesterone secretion by pig corpus luteum in vitro

Talavera¹,

Chew²

1988

Reproduction

View full text Add to dashboard Cite

Quadruplicate wells of pig luteal cells were incubated for 24 h in the presence of different concentrations of retinol, beta-carotene (0, 1 x 10(-5), 1 x 10(-6) and 1 x 10(-7) M) or retinoic acid (0, 1 x 10(-6), 1 x 10(-7) and 1 x 10(-8) M). In addition, the responsiveness of luteal cells to LH challenge was also evaluated. Progesterone was assayed in the media. Cell viability was estimated using trypan blue exclusion and showed over 95% viability. In the presence of LH, progesterone content in the medium was increased by 7-fold. As compared to their respective controls, all concentrations of retinoic acid and beta-carotene increased progesterone content in the media. The highest level of stimulation was observed with 1 x 10(-6) M-retinoic acid (5-fold increase) and 1 x 10(-7) M-beta-carotene (10-fold increase). Only 1 x 10(-5) M-retinol stimulated progesterone secretion (over 3-fold). Therefore, retinol, retinoic acid and beta-carotene stimulate progesterone secretion by pig luteal cells in vitro.

show abstract

Section: Discussionsupporting

confidence: 95%

Comparative role of retinol, retinoic acid and -carotene on progesterone secretion by pig corpus luteum in vitro

Talavera¹,

Chew²

1988

Reproduction

View full text Add to dashboard Cite

show abstract

“…While an optimal intake of BC is hypothesized to have positive effects upon reproductive outcomes both in ruminant (Arellano-Rodriguez et al 2007) and monogastric (Krammer and Aurich 2010) species, results have been contradictory, with studies reporting both positive (Kawashima et al 2009(Kawashima et al , 2012 and negative (Folman et al 1987) effects. Nonetheless, a positive relationship between BC supplementation, metabolic and endocrine status as well as reproductive outcomes has been previously proposed.…”

Section: Discussionmentioning

confidence: 99%

Beta-carotene supplementation positively affects selected blood metabolites across time around the onset of puberty in goats

Meza-Herrera¹,

Pacheco-Alvarez²,

Castro³

et al. 2017

CZECH J ANIM SCI

View full text Add to dashboard Cite

Meza-Herrera C.A., Pacheco-Alvarez P., Castro O.E., Macias-Cruz U., Avendaño-Reyes L., Mellado M., VelizDeras F.G., Contreras-Villarreal V., Abad-Zavaleta J., Rodriguez-Martinez R., Arellano-Rodriguez G. (2017): Beta-carotene supplementation positively affects selected blood metabolites across time around the onset of puberty in goats. Czech J. Anim. Sci., 62, 22-31.The possible effect of beta-carotene supplementation upon peripubertal changes in serum concentrations across time for total protein (TP), urea (UR), cholesterol (CHOL), and glucose (GLU) around puberty onset was evaluated. The experiment was carried out from June to November and prepubertal goats (n = 17, 3 months old, 7/8 Saanen-Alpine, 1/8 Criollo) were randomly assigned to: (1) beta-carotene group (BC) (n = 9; 17.3 ± 1.0 kg live weight (LW), 3.3 ± 0.12 body condition score (BCS), oral supplementation with 50 mg beta-carotene per day per goat) and (2) control group (CC) (n = 8; 16.1 ± 1.0 kg LW, 3.1 ± 0.12 BCS). Serum blood samples were collected along the experiment to quantify progesterone concentrations (P4) through radioimmunoassay, while TP, UR, CHOL, and GLU through spectrophotometric analyses. No differences (P > 0.05) occurred between treatments regarding LW and BCS, and TP (67.6 ± 2.4 g/l), UR (3.8 ± 0.17 mmol/l), GLU (5.06 ± 0.09 mmol/l), and CHOL (1.62 ± 0.07 mmol/l) concentrations. However, while a treatment × time interaction occurred between treatments for TP, GLU, CHOL (P < 0.05) favouring the BC group, an increased serum UR levels occurred in the CC group. Nonetheless, such general serum metabolite profile was related neither to the age

show abstract

“…Positive responses in dairy cow fertility and lactation performance have been observed when β-carotene was supplemented after calving (Aréchiga et al, 1998;De Ondarza et al, 2009), although absent (Bindas et al, 1984;Akordor et al, 1986) or negative (Folman et al, 1987) effects on reproduction have been reported. Kaewlamun et al (2011) and Wang et al (2013) have reported benefits in uterine health of cows supplemented with β-carotene before calving.…”

Section: Introductionmentioning

confidence: 94%

Supplementation of prepartum dairy cows with β-carotene

Oliveira

Guerreiro

Morais

et al. 2015

Journal of Dairy Science

View full text Add to dashboard Cite

The prepartum supplementation of dairy cows with β-carotene was evaluated. Cows were blocked by parity and expected calving date and assigned to a treatment: β-carotene (1.2 g/cow per d) or control (no supplementation). The same total mixed ration batch was offered to all cows, and β-carotene was top dressed to individual cows once per day. The data set contained 283 Holsteins that received a treatment for >14 d (29.1±6.9 d). Frequency distributions were analyzed with the GENMOD procedure of SAS using logistic regression for binomial data. Continuous variables were analyzed with the MIXED procedure of SAS. Within parity, nonparametric estimates of the survivor function for reproductive variables were computed using the product-limit method of the Kaplan-Meier method with the LIFETEST procedure of SAS. Plasma β-carotene concentration before supplementation was similar between supplemented and nonsupplemented cows (2.99µg/mL) and peaked at 3.26±0.175µg/mL on d -15±2.4 precalving for supplemented cows (2.62±0.168µg/mL for control). Colostrum density, milk yield, and milk composition were similar between treatments. β-Carotene tended to increase milk protein content from 2.90 to 2.96% and to decrease the proportion of primiparous cows with a milk fat to protein ratio >1.5 from 22.6 to 6.4%. The proportion of primiparous and multiparous cows with difficult calving, metritis, progesterone >1 ng/mL at 21 d and at 42 d in lactation, % conception at first service, and % pregnancy at 90 and 150 d in lactation were similar between treatments. A trend for decreased incidence of somatic cell count >200,000 cells/mL was present in multiparous cows supplemented with β-carotene (38.9% vs. 28.1%). β-Carotene was associated with a reduction in the proportion of multiparous cows with retained placenta 12 h postpartum from 29.9 to 21.7%; time of placenta release was 392 min (340 to 440) for β-carotene and 490 min (395 to 540) for control (median and 95% confidence interval). For primiparous cows, placenta release was not affected by β-carotene (incidence was 15.4%). The intervals from calving to first estrus, to first service, and to conception were not affected by β-carotene supplementation in either parity. However, independent of treatment, cows with improved reproductive efficiency had increased postpartum β-carotene concentration in plasma. The prepartum supplementation of β-carotene increased plasma concentration around calving. No response in milk yield or reproductive performance was detected. Beta-carotene supplementation was associated with a lower incidence of retained placenta in multiparous cows.

show abstract

Adverse Effect of β-Carotene in Diet on Fertility of Dairy Cows

Cited by 39 publications

References 13 publications

Comparative role of retinol, retinoic acid and -carotene on progesterone secretion by pig corpus luteum in vitro

Comparative role of retinol, retinoic acid and -carotene on progesterone secretion by pig corpus luteum in vitro

Beta-carotene supplementation positively affects selected blood metabolites across time around the onset of puberty in goats

Supplementation of prepartum dairy cows with β-carotene

Contact Info

Product

Resources

About