Adverse Effects of Depression on Glycemic Control and Health Outcomes in People with Diabetes

Pouwer, Frans; Nefs, Giesje; Nouwen, Arie

doi:10.1016/j.ecl.2013.05.002

Cited by 120 publications

(107 citation statements)

References 71 publications

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“…This proposal deserves some further attention. Chronic stress after cancer diagnosis can contribute to the development of major depression [5], which is relatively common in patients with cancer or diabetes [6,7]. Depression symptoms include decreased concentration, poor memory, loss of appetite, weight loss, pessimism, loss of interest and energy loss.…”

Section: Gld Glucose-lowering Drugsmentioning

confidence: 99%

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms

Pouwer

2015

Diabetologia

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Section: Gld Glucose-lowering Drugsmentioning

confidence: 99%

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms

Pouwer

2015

Diabetologia

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“…Longitudinal studies have also shown that depressed people with diabetes have a higher risk of developing microvascular and macrovascular complications and have higher mortality rates [8,9]. The mechanisms that link depression and poor outcomes in diabetes are still unclear and understudied, particularly in people with type 1 diabetes.…”

Section: Mechanisms Associated With Depression and Poor Diabetic Outcmentioning

confidence: 99%

“…However, diet quality, medication use and glucose monitoring were also negatively affected [10]. Biological mechanisms associated with poor diabetic outcomes in depressed individuals with diabetes most likely involve poor glycaemic control, dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and low grade inflammation [8][9][10][11][12].…”

Section: Mechanisms Associated With Depression and Poor Diabetic Outcmentioning

confidence: 99%

Depression: a common and burdensome complication of diabetes that warrants the continued attention of clinicians, researchers and healthcare policy makers

Pouwer

2016

Diabetologia

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There is ample evidence that depression is a common comorbid health issue in people with type 1 or type 2 diabetes. Reviews have also concluded that depression in diabetes is associated with higher HbA 1c levels, less optimal self-care behaviours, lower quality of life, incident vascular complications and higher mortality rates. However, longitudinal studies into the course of depression in people with type 1 diabetes remain scarce. In this issue of Diabetologia, Kampling and colleagues (doi:10.1007/s00125-016-4123-0) report the 5 year trajectories of depression in adults with newly diagnosed type 1 diabetes (mean age, 28 years). Their baseline results showed that shortly after the diagnosis of type 1 diabetes a major depressive episode was diagnosed in approximately 6% of participants, while 8% suffered from an anxiety disorder. The longitudinal depression data showed that, in a 5 year period, 79% reported no depressive symptoms at any time, while 7% had a high depression score that improved and 14% reported worsening of depressive symptoms. Here, the clinical relevance of these findings is discussed and areas for further research are described.

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“…Depression and anxiety in diabetic patients is common and may affect 10% to 30% of people. Depression in people with diabetes may be associated with a number of potential and demographic factors; of these factors age, the use of insulin, diabetes type, and the duration of diabetes can be noted (15). Depression and anxiety are modifiable risk factors and treatment, then, can improve blood sugar control and health outcomes for Copyright © 2017, Qazvin University of Medical Sciences.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Anxiety and Depression in Diabetic Patients: A Comparative Study

Javadi¹,

Ziaee²,

Yazdi³

et al. 2017

Biotech Health Sci

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Background: Living with diabetes and managing it can have substantial emotional burden on individuals. These changes might affect individuals' lives in terms of stress and depression. The purpose of this study was to determine the prevalence of stress and depression among diabetic women who referred to endocrine clinic of Qazvin in 2014. Methods: For this purpose, 250 patients (125 individuals suffering from diabetes and 125 individuals as a control group) participated in this study. All individuals completed the beck depression inventory and the cattell anxiety inventory. In addition to these, demographic and clinical records were collected from their medical records and were analyzed by appropriate statistical methods. Results: In terms of the Maximum of mild anxiety there were 52 diabetic individuals (41.6%) versus 69 individuals of the control group (55.2%); in terms of Moderate-severe anxiety there were 73 cases (58.4%) versus 56 patients (44.8%) (P value = 0.031). In studying the Maximum of mild depression, there were 43 patients (34.4%) versus 92 (73.6%); in terms of Moderate-severe depression, there were 82 patients (65.6%) versus 33 (26.4%) (P value = 0.001). On a closer examination among age, type of diabetes, duration of diabetes, and insulin injections; only the duration of having diabetes was significantly associated with depression as one of the mental health variables. Conclusions: This study showed that anxiety and depression are significantly more common among diabetic patients in comparison to the control group in the city of Qazvin; therefore, it is necessary to develop primary care by a system based on the reaction, so that an effective treatment for mental health would take place and, ultimately, the impact of these interventions should be studied.

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Adverse Effects of Depression on Glycemic Control and Health Outcomes in People with Diabetes

Cited by 120 publications

References 71 publications

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms

Depression: a common and burdensome complication of diabetes that warrants the continued attention of clinicians, researchers and healthcare policy makers

Prevalence of Anxiety and Depression in Diabetic Patients: A Comparative Study

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