Abstract:SummarySecondary phosphine oxides react with vinyl sulfides (both alkyl- and aryl-substituted sulfides) under aerobic and solvent-free conditions (80 °C, air, 7–30 h) to afford 1-hydroxy-2-(organosulfanyl)ethyl(diorganyl)phosphine oxides in 70–93% yields.
A stoichiometric C–H activation/decarbonylation of salicylaldehyde by [(η6‐p‐cymene)RuCl2]2 gave a carbonyl derivative [(η6‐p‐cymene)RuCl(CO)(Ph‐O)] (1) without the use of CO gas. A variety of polar phosphines were then incorporated into compound 1 to give new RuII cationic catalysts, [(η6‐p‐cymene)Ru(CO)(Ph‐O)L]BF4 (2–8). These were used to catalyse the hydrothiolation of alkynes with a range of thiols in aqueous THF to give anti‐Markovnikov E‐linear vinyl sulfides in high yields.
Secondary phosphine chalcogenides mildly (no catalysts and solvents, 20-65 °C, 0.25-65.5 h) react with aldimines to deliver the hitherto unknown α-aminophosphine oxides, sulfides and selenides in good to excellent yields.
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