Aerosol direct fluorination: Direct synthesis of perfluorinated glyme ethers

Estimation and analysis of the rheological properties of a perfluoropolyether through molecular dynamics simulation

“…Therefore, it is fair to say that, at the lowest temperature investigated (253 K), we are well above the pour point of C 8 F 18 O 4 . The compound under investigation was synthesized through aerosol direct fluorination [22]. It has a boiling point 105.6 8C at 757 mmHg, and a density of 1.62 g/ml at 293 K, which were experimentally measured by Crawford and Adcock [23].…”

Aerosol direct fluorination: a developing synthesis technology and an entry level mechanistic tool. A short review

“…The aerosol fluorinator produces excellent yields of perfluorinated alkanes, ethers, ketals, alkyl chlorides, and acyl fluorides (from acyl chlorides and fluorides or esters) and moderate yields of perfluorinated esters and ketones, including the highly branched ketones F-pinacolone and F-tert-butyl F-isobutyl ketone ("F-provalone") and the perfluorinated ortho esters, F-tetramethyl-and F-ethylene orthocarbonates (Adcock et al, 1981(Adcock et al, -1985.…”

“…Ethers are among the most stable and easily fluorinated groups of molecules. A large variety of ethers have been perfluorinated by the method ranging from simple methoxyalkanes and cyclic ethers (Adcock et al, 1981; to the "glyme" polyethers up to tetraglyme (Adcock and Cherry, 1985). For example, 1,4-dioxane produces its perfluoro analogue in 90% effluent purity and 70% yield with less than 5% fragmentation or ring cleavage.…”