Affective disorders and ABO blood types

Abstract

Results of the present study provide evidence of: 1) a positive association between bipolar affective disorder and blood type O and a corresponding negative association between the former and blood type A, 2) a positive association between unipolar affective disorder and blood type O, and 3) a positive association between involutional depression and blood type A and a corresponding negative association between the former and blood types B and O. Sex does not appear to modify the ABO blood types' distribution in patients with bipolar, unipolar affective disorder, or involutional depression, and the same holds for early- or late-onset of the illness in patients with bipolar or unipolar affective disorders. Findings in the present study do not support the validity of the bipolar-unipolar distinction of affective disorders, and provide evidence in favour of the view that involutional depression is a genetically distinct nosological entity.

Serological Markers in Unipolar and Bipolar Affective Disorders

“…The results obtained with regard to the association between unipolar affec tive disorder and phenotype A [Shapiro et al, 1977] as well as those regarding the bi polar affective disorder and phenotype O [Parker et al, 1961;Masters, 1967;Mendlewiczet al, 1974;Shapiro et al, 1977;Rinieris et al, 1979;Singh et al, 1979] are in agreement with some previous studies. Re garding the distribution of haptoglobin genotypes, there is an increase of homozy gotes (2-2) and decrease of heterozygotes (2-1) in bipolar affective disorder (table II).…”

“…The unipolar affective dis order was found associated with blood group A [Shapiro el al., 1977], blood group B [Beckman et al, 1978b] and blood group O [Rinieriset al, 1979]. On the other hand, some investigators have failed to reveal any relationship between affective disor ders and ABO blood groups [Thomas and Hewitt, 1939;Bourgeois and Trejaut, 1967;Gaekwad et al, 1972;James et al, 1977], Studies have also been reported regard ing the association between affective dis orders and serum protein and red cell en zyme polymorphism [Lange, 1970;Beck man et al, 1978a;Balgir, 1983a], Except for four studies [Shapiro et al, 1977;Beckman et al, 1978a, b;Rinieris et al, 1979;Singh et al, 1979], all other in vestigators have treated manic-depressive psychosis as a single disease entity [for more details see Balgir, 1983b].…”

“…Associations between bipolar affective disorder and blood group AB [Diebold, 1976], blood group A [Flemenbaum and Larson, 1976], blood group B [Tanna and Winokur, 1968;Beckman et al, 1978b] and blood group O [Parker et al, 1961;Masters, 1967;Mendlewicz et al, 1974;Shapiro et al, 1977;Rinieris et al, 1979;Singh et al, 1979] have been reported. The unipolar affective dis order was found associated with blood group A [Shapiro el al., 1977], blood group B [Beckman et al, 1978b] and blood group O [Rinieriset al, 1979].…”

Eye Color, Hair Color, Blood Type, and the Rhesus Factor: Exploring Possible Genetic Links to Sexual Orientation

“…Nevertheless, some studies have reported statistical relationships between blood types and other aspects of human personality. For example, several studies have found unusually high rates of manic depression among persons with the O blood type (Mendlewicz, Massart-Guiot, Wilmotte, & Fleiss, 1974;Parker, Theilie, & Spielberger, 1961;Rinieris, Stefanis, Lykouras, & Varsou, 1979;Shapiro, Rafaelsen, Ryder, Svejgaard, & Sorensen, 1977) with one failure to replicate (Masters, 1967). Also, studies have reported unusually high rates of cigarette smoking among persons with Arch Sex Behav (2008) 37:145-149 147 both B and AB blood types (Cohen & Thomas, 1962), a propensity for persons with A blood type to score high on a personality measure of ''tender-mindedness'' (Cattell, Boutourline, Young, & Hundleby, 1964), and high rates of suicide among individuals with O blood type (Voracek, 2004).…”

Διαταραχες Της Χρωματικης Αντιληψης Σε Ασθενεις Με Συναισθηματικες Ψυχωσεις. (Συγκριτικη Μελετη Με Σχιζοφρενεις Και Δειγμα Του Γενικου Πληθυσμου)

“…Οί έρευνες γιά τήν πιθανότητα ύπαρξης συνδυασμού μεταξύ Συναι σθηματικών Ψυχώσεων καί ομάδων αίματος ΑΒΟ, έδωσαν αντιφατικά α ποτελέσματα (Rinieris 1979).…”