Afferent Connections of the Corpus cerebelli in Holocentrid Teleosts

Xue, Hao; Yamamoto, Naoyuki; Yang, Chun-Ying; Imura, Kosuke; Ito, Hironobu

doi:10.1159/000080244

Cited by 28 publications

(39 citation statements)

References 72 publications

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“…1G-H, 2J). Similar results have been reported as the origins of afferents to the CC in green sunfish (Lepomis cyanellus), tilapia (O. niloticus), and squirrelfish [Wullimann and Northcutt, 1988;Imura et al, 2003;Xue et al, 2004]. Besides these cells, a few cells were ipsilaterally labeled in the GGL of the vcC (Fig.…”

Section: Injections Into the DCCsupporting

confidence: 88%

“…For subdivisions of the CC, we adopted the terminology of Imura et al [2003] and Xue et al [2004]. Other relevant terms are additionally introduced with citations.…”

Section: Nomenclaturementioning

confidence: 99%

“…Afferent fiber connections to the corpus cerebelli (CC) have been reported in several teleost species [Finger, 1978a[Finger, , b, 2000Ito et al, 1982;Meek et al, 1986;Northcutt, 1988, 1989;Ito and Yoshimoto, 1990;Wullimann and Meyer, 1993;Imura et al, 2003;Xue et al, 2004Xue et al, , 2005Folgueira et al, 2006]. In those reports, some authors have described topographical organizations of the afferent projections of the CC.…”

Section: Introductionmentioning

confidence: 99%

“…A number of studies have reported topographical projections of mossy fibers to the CC. Xue et al [2004] documented that afferent connections of the dorsal and ventral lobes of the holocentrid CC were topographically organized. The dorsal lobe received input from a medial portion of the nucleus paracommissuralis (NPC) and a rostral portion of the nucleus lateralis valvulae (NLV), while the ventral lobe received input from the entire NPC and a medial portion of the NLV.…”

Section: Introductionmentioning

confidence: 99%

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Fiber Connections of the Caudal Corpus Cerebelli, with Special Reference to the Intrinsic Circuitry, in a Teleost (Oreochromis niloticus)

Imura

Yamamoto²,

Yoshimoto³

et al. 2017

Brain Behav Evol

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The caudal part of the corpus cerebelli of Nile tilapia can be divided into dorsal and ventral regions. The granule cell layer of the dorsal (dGL) and ventral (vGL) regions of the caudal corpus cerebelli is known to receive indirect inputs from the telencephalon relayed by the nucleus paracommissuralis. The descending pathways are topographically organized, and the dGL and vGL receive inputs from different dorsal telencephalic parts. The caudal corpus cerebelli, in turn, projects extracerebellar efferents. However, it remains unknown how the descending telencephalic inputs are processed within the cerebellum. Therefore, the present study investigated intrinsic connections of the caudal corpus cerebelli by injecting neural tracers into the molecular layer of dorsal and ventral regions. Injections of tracers into the ventral molecular layer resulted in labeled cells in the vGL and the ganglionic layer of the ventral corpus. The axonal trajectories from labeled cells in the ganglionic layer were analyzed in detail via single-axon reconstructions, which suggested that the terminal portions were confined to the ganglionic layer of the dorsal corpus. No labeled terminals were observed outside the caudal corpus cerebelli. Tracer applications to the dorsal molecular layer resulted in labeled cells not only in the ganglionic layer and the granule cell layer of the dorsal corpus but also in the ganglionic layer of the ventral corpus. The latter finding confirms the presence of intrinsic projections from the ventral region to the dorsal region in the caudal corpus cerebelli. We further revealed that the intrinsic projection neurons are Purkinje cells by immunohistochemistry for zebrin II (aldolase C), which is a marker of Purkinje cells, combined with tracer injections into the dorsal corpus. Unlike injections into the ventral corpus, injections into the dorsal corpus resulted in labeled terminals in extracerebellar structures, such as the nucleus of the medial longitudinal fascicle and reticular formation. The present study suggests that indirect inputs from different telencephalic parts received and processed by distinct regions of caudal corpus cerebelli are sent out of the corpus through the efferent neurons in the dorsal corpus.

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Section: Injections Into the DCCsupporting

confidence: 88%

“…For subdivisions of the CC, we adopted the terminology of Imura et al [2003] and Xue et al [2004]. Other relevant terms are additionally introduced with citations.…”

Section: Nomenclaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fiber Connections of the Caudal Corpus Cerebelli, with Special Reference to the Intrinsic Circuitry, in a Teleost (Oreochromis niloticus)

Imura

Yamamoto²,

Yoshimoto³

et al. 2017

Brain Behav Evol

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“…The tegmental nuclei-derived from the atoh1a + neuronal progenitors in zebrafish include the secondary gustatory/viscerosensory nuclei and possibly the nuclei isthmi . The nuclei isthmi project to the optic tectum (Striedter and Northcutt, 1989;Northmore, 1991;Xue et al, 2004), while the secondary gustatory/viscerosensory nuclei have connections with the hypothalamus (Rink and Wullimann, 1998;Folgueira et al, 2003;Kani et al, 2010). A contribution of the URL progenitors to the tegmental nuclei, including the secondary gustatory/ viscerosensory nuclei, nuclei isthmi, and superior reticular nuclei, was also shown by tracing in the Tg(wnt1:Gal4-VP16), Tg(UAS:EGFP) transgenic line, and the migration was shown to be dependent on polysialic acid Volkmann et al, 2010).…”

Section: Characterization and Development Of Cerebellar Neuronsmentioning

confidence: 83%

Development of the cerebellum and cerebellar neural circuits

Hibi

Shimizu

2012

Developmental Neurobiology

141

114

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The cerebellum, a structure derived from the dorsal part of the most anterior hindbrain, is important for integrating sensory perception and motor control. While the structure and development of the cerebellum have been analyzed most extensively in mammals,recent studies have shown that the anatomy and development of the cerebellum is conserved between mammals and bony fish (teleost) species, including zebrafish. In the mammalian and teleost cerebellum,Purkinje and granule cells serve, respectively, as the major GABAergic and glutamatergic neurons. Purkinje cells originate in the ventricular zone (VZ), and receive inputs from climbing fibers. Granule cells originate in the upper rhombic lip (URL) and receive inputs from mossy fibers. Thus, the teleost cerebellum shares many features with the cerebellum of other vertebrates, and isa good model system for studying cerebellar function and development. The teleost cerebellum also has features that are specific to teleosts or have not been elucidated in mammals, including eurydendroid cells and adult neurogenesis. Furthermore, the neural circuitry in part of the optic tectum and the dorsal hindbrain closely resembles the circuitry of the teleost cerebellum; hence,these are called cerebellum-like structures. Here we describe the anatomy and development of cerebellar neurons and their circuitry, and discuss the possible roles of the cerebellum and cerebellum-like structures in behavior and higher cognitive functions. We also consider the potential use of genetics and novel techniques for studying the cerebellum in zebrafish.

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Serotonin‐immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus

Biradar

Ganesh

2023

The Anatomical Record

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Serotonin (5‐HT) is an evolutionarily conserved monoaminergic neurotransmitter found in the central nervous system and peripheral nervous system across invertebrates and vertebrates. Although the distribution of 5‐HT‐immunoreactive (5‐HT‐ir) neurons is investigated in various fish species, the organization of these neurons in cichlid fishes is poorly understood. These fish are known for their adaptability to diverse environments, food habits, and complex mating and breeding behaviors, including parental care. In this paper, we describe the organization of 5‐HT‐ir neurons in the brain of the cichlid fish Oreochromis mossambicus. Aggregations of 5‐HT‐ir neurons were spotted in the granule cell layer of the olfactory bulb and near the ventricular border in the preoptic area and magnocellular subdivisions of the nucleus preopticus. Although the presence of 5‐HT‐ir cells and fibers in the hypothalamic and thalamic regions, cerebellum, and raphe nuclei was comparable to that of other teleosts, the current study reveals the occurrence of 5‐HT‐ir cells and fibers for the first time in some areas, such as the nucleus posterior tuberis, nucleus oculomotorius, and nucleus paracommissuralis in the tilapia. While the presence of 5‐HT‐ir cells and fibers in gustatory centers suggests a role for serotonin in the processing of gustatory signals, distinctive pattern of 5‐HT immunoreactivity was seen in the telencephalon, pretectal areas, mesencephalic, and rhombencephalic regions, suggesting a cichlid fish specific organization of the serotonergic system. In conclusion, the 5‐HT system in the tilapia brain may serve several neuroendocrine and neuromodulatory roles, including regulation of reproduction and sensorimotor processes.

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Afferent Connections of the Corpus cerebelli in Holocentrid Teleosts

Cited by 28 publications

References 72 publications

Fiber Connections of the Caudal Corpus Cerebelli, with Special Reference to the Intrinsic Circuitry, in a Teleost (<b><i>Oreochromis niloticus</i></b>)

Fiber Connections of the Caudal Corpus Cerebelli, with Special Reference to the Intrinsic Circuitry, in a Teleost (<b><i>Oreochromis niloticus</i></b>)

Development of the cerebellum and cerebellar neural circuits

Serotonin‐immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus

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