Aflatoxins in Animal and Human Health

Robens, Jane F.; Richard, J. L.

doi:10.1007/978-1-4613-9751-9_3

Cited by 164 publications

(91 citation statements)

References 75 publications

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“…There was no dead fetus in any group. Avian species are more susceptible than other affected species, such as dogs, cattle, swine, and humans, to aflatoxicosis (Robens and Richard, 1992). Aflatoxin and fusariotoxin are often responsible for avian mycotoxicosis.…”

Section: Mechanisms Of Toxicity In Petsmentioning

confidence: 99%

Aflatoxins in Pet Foods: A Risk to Special Consumers

Aquino¹,

Corrêa²

2011

Aflatoxins - Detection, Measurement and Control

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Section: Mechanisms Of Toxicity In Petsmentioning

confidence: 99%

Aflatoxins in Pet Foods: A Risk to Special Consumers

Aquino¹,

Corrêa²

2011

Aflatoxins - Detection, Measurement and Control

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“…Aflatoxins-mycotoxins produced by Aspergillus flavus Link and Aspergillus parasiticus Speare-are highly toxic and carcinogenic 12,20 . Aflatoxin is metabolized to epoxide by liver cytochrome P450.…”

Section: Introductionmentioning

confidence: 99%

Aspergillus flavus Producing Aflatoxins Isolated from Materials of Commercial Feed in Japan

Uegaki

Tsukiboshi

Cai

2010

JARQ

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To investigate both aflatoxin contamination in feed produced in Japan and the distribution and movement of aflatoxin-producing fungi in the feed, a survey experiment was performed. Aspergillus fungi were isolated from imported Sudan grass hay, a material used to make total mixed ration (TMR) in Japan. HPLC analysis showed that one isolate produced aflatoxins B 1 and B 2 . Isolates were identified as A. flavus and A. terreus from their morphologies, rDNA-ITS sequences and aflatoxin production. No aflatoxins were detected in the Sudan grass hay source of the isolates or the fermented TMR made from the Sudan grass as one of the raw materials. The fermentation quality of the TMR was good after ensilage for over 60 days, as indicated by increased lactic acid and decreased pH. Only lactic acid bacteria and Bacillus survived in the fermented TMR; no fungi or yeasts were detected. Fermentation is important in preventing aflatoxin contamination of silage.

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“…The major source of exposure to AF is via the ingestion of contaminated food and feed. Chronic exposure to AF may not only significantly alter animal productivity, but also impose a great risk to the consumer (Robens & Richard 1992). Pigs are highly sensitive to the effects of AF, and exposure to AF-contaminated feed seriously affects the economy of the swine industry.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of two different types of montmorillonite to reduce the toxicity of aflatoxin in pigs

Shi¹,

Wang

et al. 2007

New Zealand Journal of Agricultural Research

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Experim ents were conducted to compare the efficacy ofmontmorillonite (M) andmontmorillonite nanocomposite (MN) to reduce the toxicity of aflatoxin (AF) in growing/finishing pigs. A total of 144 weaned pigs were assigned to six dietary treatment groups (0 g of adsorbents and 0 mg of AF/kg feed; 3 g of M/kg feed; 3 g of MN/kg feed; 0.11 mg of AF/kg feed; 0.11 mg of AF plus 3 g of M/kg feed; and 0.11 mg of AF plus 3 g of MN/kg feed). Compared to the control, AF alone decreased average daily gam (ADG) by 12.9% (P < 0.05), and increased feed/gain ratio by 7.54% (P < 0.05). Improvements in average daily gain and feed/gain ratio by 13.0 and 4.80% (P < 0.05) by the addition of MN to the AF diet demonstrated the ability of MN to reduce the toxic effects of AF. However, the addition of M did not dim inish the growth inhibitory effects of AF (P > 0.05). AF intake increased relative weights of liver, kidney, spleen and pancreas by 8.24, 27.3, 41.2 and 42.9% (P < 0.05), and resulted in significant alterations of serum biochemical values and enzymatic activities (P < 0.05). Pigs fed the MN with AF diet had appreciable improvements in AF-induced organ lesions and aberrations in serum profiles (P < 0.05), whereas pigs fed the M with AF diet had relative organ weights and serum profiles similar to those of pigs fed AF alone (P > 0.05), which indicated beneficial effects of MN and nonprotective effects of M. These findings suggested that feeding MN can effectively prevent the negative effects associated with aflatoxicosis in pigs.

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Aflatoxins in Animal and Human Health

Cited by 164 publications

References 75 publications

Aflatoxins in Pet Foods: A Risk to Special Consumers

Aflatoxins in Pet Foods: A Risk to Special Consumers

Aspergillus flavus Producing Aflatoxins Isolated from Materials of Commercial Feed in Japan

Efficacy of two different types of montmorillonite to reduce the toxicity of aflatoxin in pigs

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