Ag(I)-coordinated hairpin DNA for homogenous electronic monitoring of hepatitis C virus accompanying isothermal cycling signal amplification strategy

Lu, Minghua; Liang, Xu; Zhang, Xiaona; Xiao, Rui; Wang, Youmei

doi:10.1016/j.bios.2015.05.058

Cited by 24 publications

(4 citation statements)

References 37 publications

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“…Altın nanopartiküllerinin kullanıldığı sinyal amplifikasyon yöntemlerin örnekleri HBV ve influenza gibi viral enfeksiyonlar için tanımlanmıştır (9,48). Ayrıca, hairpin DNA biyosensörleri ve sinyal amplifikasyon tekniklerinin kombinasyonunun içeren yaklaşımların HCV, HIV ve HTLV-1 (human T-lymphotropic virus-1) gibi viral enfeksiyonların tanısında kullanılabilirliği ile ilgili çalışmalar da yapılmıştır (49,50).…”

Section: Diğer Sinyal Amplifikasyon Teknikleriunclassified

Si̇nyal Ampli̇fi̇kasyon Tekni̇kleri̇ Ve Tanisal Vi̇roloji̇deki̇ Uygulamalari

Şahiner¹,

Gümral²

2020

J Istanb Fac Med

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Section: Diğer Sinyal Amplifikasyon Teknikleriunclassified

Si̇nyal Ampli̇fi̇kasyon Tekni̇kleri̇ Ve Tanisal Vi̇roloji̇deki̇ Uygulamalari

Şahiner¹,

Gümral²

2020

J Istanb Fac Med

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“…Among these, many are those based on different signal amplification procedures that allow to achieve very low detection limits [72][73][74][75][76][77][78][79][80]. This, however, generally requires the addition of exogenous, label containing secondary probes and, typically multi-component deposition/amplification steps.…”

Section: Dna-based Electrochemical Disposable Sensorsmentioning

confidence: 99%

Electrochemical biosensors based on nanomodified screen-printed electrodes: Recent applications in clinical analysis

Arduini

Micheli

Moscone

et al. 2016

TrAC Trends in Analytical Chemistry

336

166

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A B S T R A C TThis review addresses recent advances in the development of screen-printed electrode based biosensors modified with different nanomaterials such as carbon nanotubes, graphene, metallic nanoparticles as gold, silver and magnetic nanoparticles, and mediator nanoparticles (Prussian Blue, Cobalt Phthalocyanine, etc.), coupled with biological recognition elements such as enzymes, antibodies, DNA and aptamers to obtain probes with improved analytical features. Examples of clinical applications are illustrated, together with examples of paper-based electrochemical devices, of multiple detections using arrays of screen printed electrodes, and of the most recent developments in the field of wearable biosensors. Also the use of smartphones as final detectors is briefly depicted.

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“…Many ssDNAs have been artificially synthesized [ 14 , 15 , 16 ] and developed as the so-called aptamer sensors [ 17 , 18 , 19 , 20 , 21 ] because of the outstanding affinity and specificity to both nucleic and non-nucleic acid species. Among them, anti-Hg 2+ ssDNA was used as a model.…”

Section: Introductionmentioning

confidence: 99%

Influences of Probe’s Morphology for Metal Ion Detection Based on Light-Addressable Potentiometric Sensors

Chuang

Zhou

Yin

et al. 2016

Sensors

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The sensing mechanism of binding Hg2+ into thymine-thymine (T-T) mismatched base pairs was introduced into a light-addressable potentiometric sensor (LAPS) with anti-Hg2+ aptamer as the sensing units. Three kinds of T-rich single-strand DNA (ssDNA) chains with different spacer lengths, from 0 to 12 –CH2 groups, were designed to investigate surface charge and morphological effects on the LAPS’ output. First, by comparing the responding of LAPS modified with three kinds of ssDNA, it was found that the best performance for Hg2+ sensing was exhibited by the probe without –CH2 groups. The detection limit of Hg2+ ion was 1 ppt under the optimal condition. Second, the cooperative effects of surface charge and morphology on the output were observed by the controlled experiments. The two effects were the negative charge balanced by metal cations and the morphological changing caused by the formation of T-Hg2+-T structure. In conclusion, not only the influences of the aptamer probe’s morphology and surface charge was investigated on the platform of LAPS, but also sensing Hg2+ ions was achieved for the first time by the presented aptamer LAPS.

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Ag(I)-coordinated hairpin DNA for homogenous electronic monitoring of hepatitis C virus accompanying isothermal cycling signal amplification strategy

Cited by 24 publications

References 37 publications

Si̇nyal Ampli̇fi̇kasyon Tekni̇kleri̇ Ve Tanisal Vi̇roloji̇deki̇ Uygulamalari

Si̇nyal Ampli̇fi̇kasyon Tekni̇kleri̇ Ve Tanisal Vi̇roloji̇deki̇ Uygulamalari

Electrochemical biosensors based on nanomodified screen-printed electrodes: Recent applications in clinical analysis

Influences of Probe’s Morphology for Metal Ion Detection Based on Light-Addressable Potentiometric Sensors

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