Ag(I)N bond-containing compound showing wide spectra in effective antimicrobial activities: Polymeric silver(I) imidazolate

Nomiya, Kenji; Tsuda, Kazuhiro; Sudoh, T.; Oda, Munehiro

doi:10.1016/s0162-0134(97)00006-8

Cited by 176 publications

(108 citation statements)

References 20 publications

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“…L-Cystine dimethyl ester (not containing thiol groups) did not neutralize the antibacterial activity of silver (12). Together with the observation that silver bonding to sulfur is stronger than silver bonding to nitrogen (9), these examples indicate that silver prefers sulfur bonding only when delivered by nonsulfur-containing agents; in such cases, silver compounds can become effective antibacterial agents. Besides biochemical or physiological experiments, morphological data on cell disruption caused by silver ions were published (3).…”

mentioning

confidence: 86%

“…These hypotheses can be summarized as (i) bonding of Ag to amino acids in proteins and enzymes, especially via sulfur or via nitrogen; (ii) bonding to nucleic acids and phosphates in DNA or RNA; and (iii) oxidation catalyzed by Ag. These bonding reactions can cause, e.g., structural changes in the cell wall and bacterial membrane, disruption of enzyme-catalyzed reactions, or disruption of the electron transport chain of the cell (8)(9)(10)(11). On the basis of chemical and microbiological experiments with Pseudomonas aeruginosa, it has been proposed that the mechanism of the antibacterial activity of silver closely correlated with the interactions of silver with thiol (S-H) groups (12), although other targets, such as amine (N-H) groups, have also been discussed (3,13,14).…”

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confidence: 99%

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X-Ray Absorption Near-Edge Structure (XANES) Spectroscopy Study of the Interaction of Silver Ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli

Bovenkamp

Zanzen

Krishna

et al. 2013

Appl Environ Microbiol

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e Silver ions are widely used as antibacterial agents, but the basic molecular mechanism of this effect is still poorly understood. X-ray absorption near-edge structure (XANES) spectroscopy at the Ag LIII, S K, and P K edges reveals the chemical forms of silver in Staphylococcus aureus and Escherichia coli (Ag ؉ treated). The Ag LIII-edge XANES spectra of the bacteria are all slightly different and very different from the spectra of silver ions (silver nitrate and silver acetate), which confirms that a reaction occurs. Death or inactivation of bacteria was observed by plate counting and light microscopy. Silver bonding to sulfhydryl groups (Ag-S) in cysteine and Ag-N or Ag-O bonding in histidine, alanine, and DL-aspartic acid was detected by using synthesized silveramino acids. Significantly lower silver-cysteine content, coupled with higher silver-histidine content, in Gram-positive S. aureus and Listeria monocytogenes cells indicates that the peptidoglycan multilayer could be buffering the biocidal effect of silver on Gram-positive bacteria, at least in part. Bonding of silver to phosphate groups was not detected. Interaction with DNA or proteins can occur through Ag-N bonding. The formation of silver-cysteine can be confirmed for both bacterial cell types, which supports the hypothesis that enzyme-catalyzed reactions and the electron transport chain within the cell are disrupted.

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confidence: 86%

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confidence: 99%

X-Ray Absorption Near-Edge Structure (XANES) Spectroscopy Study of the Interaction of Silver Ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli

Bovenkamp

Zanzen

Krishna

et al. 2013

Appl Environ Microbiol

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“…The diffusing ability of the silver ions on agar plate might have been limited by the formation of secondary silver compounds, which is the limitation of the Kirby Bauer technique as a quantitative tool to determine the antimicrobial activity. 32 Therefore, LB medium method was intro- duced to determine the antimicrobial activity of Ag/ PVA-PVP hydrogels quantitatively. 26 Pure PVA-PVP hydrogel and four Ag/PVA-PVP samples (Ag wt % ¼ 0.1, 0.2, 0.4, and 1.0, respectively) were tested.…”

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confidence: 99%

Preparation and antibacterial effects of PVA‐PVP hydrogels containing silver nanoparticles

Chen

et al. 2006

J of Applied Polymer Sci

210

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The poly(vinyl alcohol)/poly(N-vinyl pyrrolidone) (PVA-PVP) hydrogels containing silver nanoparticles were prepared by repeated freezing-thawing treatment. The silver content in the solid composition was in the range of 0.1-1.0 wt %, the silver particle size was from 20 to 100 nm, and the weight ratio of PVA to PVP was 70 : 30. The influence of silver nanoparticles on the properties of PVA-PVP matrix was investigated by differential scanning calorimeter, infrared spectroscopy and UV-vis spectroscopy, using PVA-PVP films containing silver particles as a model. The morphology of freeze-dried PVA-PVP hydrogel matrix and dispersion of the silver nanoparticles in the matrix was examined by scanning electron microscopy. It was found that a three-dimensional structure was formed during the process of freezing-thawing treatment and no serious aggregation of the silver nanoparticles occurred. Water absorption properties, release of silver ions from the hydrogels and the antibacterial effects of the hydrogels against Escherichia coli and Staphylococcus aureus were examined too. It was proved that the nanosilver-containing hydrogels had an excellent antibacterial ability.

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“…We have suggested that ligand-exchangeability plays a key role in a wide spectrum of the antimicrobial activities of silver(I) complexes [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, structure and antimicrobial activities of meso silver(I) histidinate [Ag2(D-his)(L-his)]n (Hhis=histidine) showing different self-assembly from those of chiral silver(I) histidinates

Kasuga

Takagi

Tsuruta

et al. 2011

Inorganica Chimica Acta

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Ag(I)N bond-containing compound showing wide spectra in effective antimicrobial activities: Polymeric silver(I) imidazolate

Cited by 176 publications

References 20 publications

X-Ray Absorption Near-Edge Structure (XANES) Spectroscopy Study of the Interaction of Silver Ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli

X-Ray Absorption Near-Edge Structure (XANES) Spectroscopy Study of the Interaction of Silver Ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli

Preparation and antibacterial effects of PVA‐PVP hydrogels containing silver nanoparticles

Synthesis, structure and antimicrobial activities of meso silver(I) histidinate [Ag2(D-his)(L-his)]n (Hhis=histidine) showing different self-assembly from those of chiral silver(I) histidinates

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