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Casso, Deborah; Buist, Diana S.M.; Taplin, Stephen H.

doi:10.1186/1477-7525-2-25

Cited by 118 publications

(30 citation statements)

References 19 publications

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“…Results from studies examining HRQOL in breast cancer survivors appear to have similar findings [35]. In fact, the mental HRQOL in our study was better than the mean MCS scores of breast cancer survivors who were on average seven years post-diagnosis.…”

Section: Discussionsupporting

confidence: 82%

“…In fact, the mental HRQOL in our study was better than the mean MCS scores of breast cancer survivors who were on average seven years post-diagnosis. The PCS values for the breast cancer survivors that had received chemotherapy were similar to the ovarian cancer survivors in our study, while breast cancer survivors who received hormonal therapy only or no systemic therapy had higher PCS than our study population [35]. …”

Section: Discussionmentioning

confidence: 52%

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Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I

Zhou

Irwin

Ferrucci

et al. 2016

Gynecologic Oncology

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Objective There are limited data on outcomes and predictors of health-related quality of life (HRQOL) of ovarian cancer survivors. Therefore, we examined the trajectory and predictors of HRQOL one- and two-years post-diagnosis in this population. Methods 365 ovarian cancer survivors, a subset of participants in the longitudinal American Cancer Society’s Study of Cancer Survivors-I, completed questionnaires at one-year post-diagnosis on sociodemographics, clinical factors, and HRQOL (SF-36). 284 women had HRQOL data at two-years post-diagnosis. In this secondary data analysis, we examined HRQOL at both time points, changes in HRQOL and predictors of HRQOL with univariate and multivariate linear regression. Results Mean mental and physical HRQOL scores one-year post-diagnosis were 49.37 (SD±11.59) and 45.96 (SD±10.89), respectively. Older age, lower income, higher disease stage, more comorbidities and greater symptom burden were associated with poorer physical functioning one year post-diagnosis. Younger age, higher stage, having an existing mental health issue, greater symptom burden, and not receiving chemotherapy were associated with poorer mental functioning. Disease recurrence between one- and two-years post-diagnosis and greater symptom burden were predictors of declining physical functioning from one- to two-years post-diagnosis. Mental functioning did not change significantly between assessments. Conclusions Overall mental and physical functioning of these ovarian cancer survivors was similar to the general population. However, lower HRQOL was associated with a number of variables, including disease recurrence, treatment status, symptom burden, age, and number of comorbidities. These findings can help health care providers identify survivors who may benefit from relevant interventions.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 52%

Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I

Zhou

Irwin

Ferrucci

et al. 2016

Gynecologic Oncology

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“…Chemotherapy also has been reported to predict impaired QOL in 5- and 10-year survivors. 51,52 QOL following specific adjuvant treatment regimens has been described in longitudinal studies with patients receiving radiation, 44,45,53 chemotherapy, 54 radiation and chemotherapy, 55,56 and endocrine therapy. 57–60 However, unlike these studies, we included an adjuvant chemotherapy*time interaction term in our analysis—in relation to receipt of BCS or mastectomy as well—allowing us to determine if, and how, the change in QOL over time differed by receipt of chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Surgery Type and Chemotherapy on Early-Stage Breast Cancer Patients’ Quality of Life Over 2-Year Follow-up

et al. 2015

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Purpose We examined the effects of surgery type and adjuvant chemotherapy on change in early-stage breast cancer patients' quality of life (QOL) over time. Methods A cohort of 549 patients (33.5% ductal carcinoma in situ, 66.5% stages I/IIA) were interviewed a mean 6.1 weeks (Time1), and 6.2 (Time2), 12.3 (Time3), and 24.4 (Time4) months following definitive breast-conserving surgery (BCS) or mastectomy. QOL was measured using the total Functional Assessment of Cancer Therapy-Breast (FACT-B). Adjusting for demographic, psychosocial, and clinical variables, multiple linear regression models estimated the associations between QOL and each of surgery type, chemotherapy and their 2-way interaction at each interview. Adjusted Generalized Estimating Equation (GEE) models tested Time1-Time4 change in QOL. Results At T2, chemotherapy (P < 0.001) and BCS (P < 0.001) were independently associated with worse QOL in adjusted linear regression, and the adverse effect of chemotherapy was prominent among patients who received BCS compared with those who received mastectomy (Pinteraction = 0.031). In the GEE model, QOL significantly improved over time among patients who received BCS (Ptrend = 0.047), mastectomy (Ptrend = 0.024), and chemotherapy (Ptrend < 0.001) but not among patients who did not receive chemotherapy (Ptrend = 0.720). All patients completed adjuvant chemotherapy and radiation by Time3. Regardless of surgery type, patients receiving chemotherapy reported lower QOL following surgery, and QOL improved after completion of adjuvant treatment. Conclusions Chemotherapy had a short-term negative impact on QOL after definitive surgical treatment regardless of surgery type. QOL rebounded after completion of adjuvant treatment.

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“…Although there are numerous reports on depression and its correlates, the relation between sociodemographic and clinical factors and depression after diagnosis of breast cancer remain controversial [1, 2, 13–15, 17]. It has been suggested that sociodemographic factors, such as age, marital status, and socioeconomic status are associated with depression [1, 2, 14, 15, 17–19].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of depression and its related factors among Chinese women with breast cancer

et al. 2009

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Background Few data are available regarding depression among Asian breast cancer survivors. Methods We estimated the prevalence of depression and its correlates among 1400 participants of a population-based cohort study of women with stage 0–IV breast cancer in Shanghai, China. Through in-person interviews conducted at 6 months and 18 months post-diagnosis and review of medical charts, information on sociodemographic and clinical factors and quality of life (QOL) were collected. Depression was measured by the 20-item Center for Epidemiologic Studies Depression Scale 18 months after diagnosis. Results Approximately 26% of participants had mild to severe depression and 13% fulfilled the criteria of clinical depression at 18 months post-diagnosis. Women with lower income were more likely to have depression than those with higher income (prevalence: 16.6% vs. 6.9% for mild depression and 17.1% vs. 5.5% for clinical depression, respectively). Depression was more common among women who were widowed (18.9%) or divorced/separated/single (16.4%) than those who were married (11.8%). Women with comorbidity were more likely to have clinical depression (17.3% vs 11.2%). Multivariate analysis showed that low income, marital status, comorbidity, and low QOL scores were independent predictors for depression. We did not find that prevalence of depression differed by menopausal status, estrogen or progesterone receptor status, disease stage, or cancer-related treatments. Conclusion Depression is common among Asian women with breast cancer. Routine screening and prevention of depression are warranted among women with breast cancer.

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Untitled

Cited by 118 publications

References 19 publications

Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I

Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I

The Effects of Surgery Type and Chemotherapy on Early-Stage Breast Cancer Patients’ Quality of Life Over 2-Year Follow-up

Prevalence of depression and its related factors among Chinese women with breast cancer

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