Agarelektrophoretische Studien zum Nachweis von
Isoenzymen der Lactatdehydrogenase in verschiedenen menschlichen Organextrakten

Scheiffarth, F; Götz, Hermann; Frick, Rahel

doi:10.1159/000458203

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…As shown in figure 1, the control thyroid tissue exhibited, in a rough measure, the intermediary type of LDH isozyme distribution pattern, but, in detail, it shifted slightly towards the H type. This is essentially consistent with the figure reported by Wróblewski [8], but not with that of Scheiffarth et al [7], who claimed the H type pattern for LDH isozyme of autopsied nor mal human thyroid tissue.…”

Section: Resultssupporting

confidence: 91%

Lactate Dehydrogenase Isozymes of Thyroid Tissue in Various Thyroid Gland Diseases

Y¹,

Fk²

1970

Enzymol Biol Clin

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Distribution of LDH isozymes of human thyroid tissues obtained from patients with hyperthyroidism, adenomatous goiter, non-malignant and malignant tumors was studied by paper (Oxoid) electrophoresis and consequent tétrazolium staining. The shift of the LDH isozyme distribution towards the M type pattern was greatest in cancer (adenocarcinoma) and less in hyperthyroidism and follicular adenoma. The normal thyroid tissue pattern was not symmetrical, but slightly shifted towards the H type. The hyperthyroid and adenomatous goiter tissues showed typical symmetrical patterns, and papillary adenoma tissues exhibited a shift towards the H type distribution.

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Section: Resultssupporting

confidence: 91%

Lactate Dehydrogenase Isozymes of Thyroid Tissue in Various Thyroid Gland Diseases

Y¹,

Fk²

1970

Enzymol Biol Clin

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“…Es ist a'ber beabsichtigt, wenigstens fiir die Immunglobuline, Antigenisolierungen und eine entsprechende Antik6rperinduktion zur Gewinnung spezifischer monovalenter Antiseren vorzunehmen. H, GStz [6,13] zugrunde.…”

Section: H G6tzunclassified

Haematology and blood clotting

Götz¹,

Bücherl²

1974

Langenbecks Arch Chiv

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Summary. The present paper deals with analyses of blood within the scope of large-scale experiments with transplanted artificial hearts in cattle.There are undertaken tests on the corpuscular elements of blood, oil plasma proteins as well as on isoenzymcs of lactic dehydrogenase and of peroxidase. There are also proved the factors of clotting system. Moreover, cross tests between erythrocytes and plasma of transplanted animals and canned blood were done, if necessary.As results, among the blood corpuscles there was found a striking changement of the crythrocytes' morphology, further, a numerical diminution of all corpuscular systems of blood, especially of thrombocytes, among the plasma proteins frequently a dysproteinaemia with fibrinogenaemia, among the isoenzymes of lactic dehydrogenase an increase of LDH I, concerning the peroxidase activity an ascendancy of the enzyme fraction within the initial hours after connection with the heart-lungsmachine, and among the clotting factors especially a prolongation of the thromboplastine time and a reduction of the fibrinogen's concentration.The cross tests showed agglutinating reactions in 15 % of all samples and haemolysis in two cases of all.These findings on blood factors may be interpreted as an expression of the injury of the different portions of blood by the plastics' surfaces as well as by changes of haemodynamic forces of streaming blood caused by the pumping function of the heart-lungs-machine. Untersucht wurden die corpuscul/~ren Elemente des Blutes, die Plasmaproteine, sowie die Isoenzyme der Lactatdehydrogenase und der Peroxidase. Aullerdem wurden die Gerinnungsfaktoren bestimmt. Des weiteren sind Kreuzproben zwischen dem Blur der Versuchstiere und der jeweils bereitgestellten Konserven vorgenom° men worden.

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Vergleichende biochemische untersuchungen an unterschiedlich aufbereiteten leberextrakten

Scheiffarth¹,

Götz²,

Grottke³

1968

Clinica Chimica Acta

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Agarelektrophoretische Studien zum Nachweis von Isoenzymen der Lactatdehydrogenase in verschiedenen menschlichen Organextrakten

Cited by 4 publications

References 6 publications

Lactate Dehydrogenase Isozymes of Thyroid Tissue in Various Thyroid Gland Diseases

Lactate Dehydrogenase Isozymes of Thyroid Tissue in Various Thyroid Gland Diseases

Haematology and blood clotting

Vergleichende biochemische untersuchungen an unterschiedlich aufbereiteten leberextrakten

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