Age and sex-related serum changes in nitric oxide: Correlations with serological markers

Serum nitric oxide metabolite levels in a general healthy population: Relation to sex and age

“…Also in agreement with our results, it has been reported that serum NO x levels are higher in young men compared with young women (Watanabe et al, 2000). On the other hand, Peinado et al (2007), studying 104 men and 96 women, have reported that there were no significant differences between serum NO x concentrations in men and women; these findings support the results of the current study regarding only the age range of over 30 years. Taking in account the number of subjects, the wide range of the ages of the subjects, and the method of sampling, it can be considered that findings of this study are more generalizable compared to the above-mentioned reports.…”

“…Serum NO x levels showed age-related changes in both genders and peaked between 50 and 59 years. This finding partly confirms those of Peinado et al (2007) who reported women aged 51-60 years, registered the highest value of NO x which may be due to their menopausal status (Watanabe et al, 2000). In present study, increased NO x levels between 50 and 59 years declined after 60 years in men but not in women.…”

Plasma nitrite/nitrate concentrations in patients with schizophrenia

“…Similarly, Peinado et al (11) found that NO concentrations undergo age and gender changes that strongly correlated with serological markers, such as those related with cardiovascular function and lipids. Contrary to our findings, Ghasemi et al (12) observed significantly higher NO metabolite concentrations in asymptomatic male non-smokers than in females, showing peak concentrations at the age of 50-59 years in both genders.…”

Shorter Telomere Length Predicts Poorer Immunological Recovery in Virologically Suppressed HIV-1–Infected Patients Treated With Combined Antiretroviral Therapy

“…37,38 This method has a sensitivity of 1 pmole and a repeatability of 65% and is superior to other methods because many samples can be analyzed sequentially without the necessity of sample prereduction. In brief, plasma samples were deproteinized with 0.8 N NaOH and 16% ZnSO 4 solutions (1/0.5/0.5).…”