Age-Period-Cohort Analysis of Liver Cancer Mortality in Korea

Park, Jihwan; Jee, Sun Ha

doi:10.7314/apjcp.2015.16.18.8589

Cited by 10 publications

(10 citation statements)

References 23 publications

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“…In this study, the total PP for liver cancer in Isfahan province was 18.5 per 100,000 persons that corresponded to a value of 20.9 for males and 16.8 for females. This is consistent with published articles that also confirmed higher values in males (15). Age reported liver cancer was 13% in patients less than 50 years and as high as 84% between 50 to 90 years.…”

Section: Discussionsupporting

confidence: 92%

Prevalence of Liver Cancer in Isfahan Province, Iran

Ghamari

Tadayon

Mazdak

2018

Indonesian Journal of Cancer

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Background: Liver cancer remains to grow worldwide. We aimed to describe the period prevalence (PP) and incidence rates (Irs) for liver cancer in Isfahan Province that is located in the center of Iran and ranked as the third province in terms of population.Methods: Information related to the Surveillance, Epidemiology, and End Results; (SEER) was collected from the Isfahan Cancer Registry. Period prevalence (PP) was calculated per 100,000 people. The cancer sites studied were defined according to the International Classification of Diseases (ICD-O; Third Edition) and recorded by topography code (C22).Result: Among all registered liver cancer patients, 57% of the 920 cases were male. The mean age of the patients was 65.9 ± 16.8 years. Reported age in 13% of the patients was less than 50 years and as high as 84% were in between 50 to 90 years. With a total PP of 18.5 per 100,000 people, this value was 24.4% higher in males when compared to females (16.8 vs. 20.9). In the previous years, incidences were 3.9 (2011-2012), 5.3 (2012-2013), 4.9 (2013-2014) and 4.2 (2014-2015) per 100,000 people. There were 89% reported deaths among the total population.Conclusion: The PP for liver cancer in male population was approximately 24.4% higher than females. There was a 7.7% increase in the Irs over the study period. Further study toward estimation of the proportion of the causes of liver cancer and deaths due to infection of hepatitis B and C virus, exposure to aflatoxin, alcohol drinking and smoking seem to be advantageous. Therefore, the plan of healthcare system should focus on greater effort toward strategic evidence-based pharmacotherapy in Isfahan province/Iran.

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Section: Discussionsupporting

confidence: 92%

Prevalence of Liver Cancer in Isfahan Province, Iran

Ghamari

Tadayon

Mazdak

2018

Indonesian Journal of Cancer

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“…However, the number of deaths resulting from the various liver diseases has changed significantly in China during the same period. While similar to the trends observed in developed countries,1 15 16 24 CLD mortality rates have declined dramatically in China, and PLC mortality rates have risen continually over the same period. Furthermore, VH mortality rates started to rise in 2004 after more than a decade of decline.…”

Section: Discussionsupporting

confidence: 67%

“…We examined the secular trends in mortality resulting from various liver diseases in mainland China from 1987 to 2016 using APC analysis, a method widely used for decomposing variations in secular trends of mortality or morbidity of diseases by age, period and cohort 3 15 16…”

Section: Methodsmentioning

confidence: 99%

Mortality trends of liver diseases in mainland China over three decades: an age-period-cohort analysis

et al. 2019

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ObjectiveTo analyse mortality trends of liver diseases in China over the past 30 years.DesignAge-period-cohort analyses were applied to liver diseases data obtained from the Chinese Health Statistics Annual Report (1987–2001) and the Chinese Health Statistics Yearbook (2003–2017).SettingGeneral population in mainland China.OutcomesMortality rates and age, period and cohort effects on three categories of liver diseases: primary liver cancer (PLC), chronic liver disease and cirrhosis (CLD), and viral hepatitis (VH).ResultsA total of 13.54 million deaths were attributable to liver diseases over the period between 1987 and 2016, resulting in an average of 36.15 deaths per 100 000 population per year. The risk of PLC mortality increased by 32.69% over the period after controlling for the effects of age and birth cohort. By contrast, the risk of CLD mortality decreased by 56.64% over the same period. The risk of VH mortality decreased first, followed by a resurgence after the period of 2002–2006. Similar mortality risk trends by age (increasing) and birth cohort (decreasing) were observed for PLC and CLD. The year 1952 represented a turning point for VH, with people born after 1950 experiencing a declining risk of VH mortality.ConclusionsChina has achieved great success in reducing the mortality of VH and CLD. However, significant challenges lie ahead in the efforts to prevent and control PLC and the resurgence of VH.

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“…However, a non-identification problem may still exist as there is a linear relationship between the age, period and cohort, which makes it difficult to estimate the unique set for every age, period and cohort effect [17]. To solve this problem, the intrinsic estimator (IE) method, which is associated with the APC model and was proposed by Yang and Fu [25], was used [17,26]. We used the Akaike information criterion (AIC) and the Bayesian information criterion (BIC) to evaluate the goodness-of-fit of the model.…”

Section: Methodsmentioning

confidence: 99%

Comparison of Secular Trends in Cervical Cancer Mortality in China and the United States: An Age-Period-Cohort Analysis

Wang

Bai

Wang

et al. 2016

IJERPH

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Abstract:Background: As one of the most common cancers in the female population, cervical cancer has ranked as the second most incident gynecological cancer in recent years, trailing only breast cancer. We aimed to assess and compare the secular trends in cervical cancer mortality in China and the United States and analyze the independent effects of chronological age, time period and birth cohort using age-period-cohort (APC) analysis. Methods: We performed an age-period-cohort analysis using the intrinsic estimator method to estimate the independent effects of age, time period, and birth cohort on cervical cancer mortality. We collected mortality data for China and the United States from the WHO Mortality Database and China Health Statistical Yearbook database. Results: We examined the general trends in cervical mortality rates in China and the United States during the periods 1988-2012 and 1953-2012, respectively. The age-standardized mortality rates (ASMRs) for cervical cancer in urban China, rural China and the U.S. showed a general decreasing trend during the observation period, except for urban China, which experienced a significant increase beginning in 2002. The mortality rates for cervical cancer in the three areas showed a general increasing trend with age, regardless of the period effect. Period effects declined steadily in both rural China (from 0.19 to −0.26) and the U.S. (from −0.20 to −0.43); however, a slight increasing trend was identified (from −0.25 to 0.33) in urban China, which indicated that the risk of mortality increased with time. Cohort effects peaked in the cohort born in 1911-1915 in both rural China and urban China, declined consistently in the cohort born before 1950, and then decreased again in the cohort born after 1976-1980. The cohort effect in the U.S. peaked in the birth cohort born in 1876-1880, then leveled off and slightly decreased in younger generations. Conclusions: Our study showed that in general, cervical cancer mortality rates increased with age and decreased with birth cohort in the U.S., while the risk of mortality was highest in the cohort born during 1946-1975 in urban China. Additionally, the risk of mortality consistently increased with age in women younger than 64 years old in urban and rural China and began to decline in older groups. Although the age and cohort effects were relatively strong, the period effect may be the key factor affecting cervical cancer mortality trends, mainly reflecting the immediate effects of effective treatment and the implementation of screening.

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Age-Period-Cohort Analysis of Liver Cancer Mortality in Korea

Cited by 10 publications

References 23 publications

Prevalence of Liver Cancer in Isfahan Province, Iran

Prevalence of Liver Cancer in Isfahan Province, Iran

Mortality trends of liver diseases in mainland China over three decades: an age-period-cohort analysis

Comparison of Secular Trends in Cervical Cancer Mortality in China and the United States: An Age-Period-Cohort Analysis

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