Age Related Changes in the Histomorphology of the Adenohypophysis of the Goat

Khatra, G. S.; Nanda, B. S.

doi:10.1111/j.1439-0264.1981.tb00521.x

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Although the compartment in the dorsal region contained either no or only a few collagen branches, the parenchyma in the middle region appeared to be supported by a coarse network of collagen branches. As the cavum hypophysis intervenes between the pars intermedia and pars distalis and the ventral surface of pars intermedia is free from pars distalis except for the lateral periphery in the goat hypophysis (Khatra and Nanda, 1981), many more collagen branches strengthen the structure of the middle region in the pars intermedia compared to the dorsal region.…”

Section: Discussionmentioning

confidence: 99%

“…As in many animal species, the goat adenohypophysis is characterized by anastomosing cell clusters and connective tissue fibers among the cell clusters (Khatra and Nanda, 1981). The aim of this study was to elucidate the characteristics of the three‐dimensional architecture and distribution of collagen types in the pars distalis, pars tuberalis, pars intermedia, and lobus nervosus of the goat hypophysis by SEM in conjunction with the cell maceration method and immunohistochemistry.…”

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confidence: 99%

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Three‐dimensional architecture and distribution of collagen components in the goat hypophysis

et al. 2004

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The three-dimensional architecture of collagen fibrils in the connective tissue framework and the distribution of collagen types in the goat hypophysis were studied by the cell maceration method in combination with scanning electron microscopy (SEM) and immunohistochemistry. The pars distalis of the adenohypophysis consisted of many cell clusters. SEM revealed that the wall of cell clusters appeared as various-sized flat bundles of collagen fibrils woven in a basket-like configuration. In the pars tuberalis, the aggregates of collagen fibrils were denser and bundles thicker compared to the pars distalis. The density of collagen fibrils changed from the pars tuberalis to pars distalis without a distinct border. The collagen framework in the pars intermedia was mainly divided into three parts, the dorsal region with large hollows, the middle region, and the ventral sheet facing the cavum hypophysis. In the lobus nervosus of the neurohypophysis, the collagen network exhibited a sponge-like appearance at low magnification. Collagen fibrils of various sizes consisted of loose wavy bundles distributed around the cavities. Immunohistochemistry revealed types I, III, IV, V, and VI collagen throughout the hypophysis. It is concluded that to maintain structural and functional integration, the components of collagen are in different configurations throughout the regions of the goat hypophysis. Anat Rec Part A 277A: 275-286, 2004.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Three‐dimensional architecture and distribution of collagen components in the goat hypophysis

et al. 2004

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Fine structural and immunohistochemical studies of goat adenohypophysial cells

1985

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The fine structure of each type of anterior pituitary cell in the male goat was studied through the application of a superimposition technique in which adjacent thick sections were used to identify individual cells beforehand by light-microscopic immunohistochemistry. A cone of the pars intermedia protrudes into the pars anterior, being surrounded by the narrow pituitary cleft; the immunohistochemical appearances of the cells forming the cone resemble those of the pars anterior. Several follicles appear in the pars anterior. Ultrastructurally GH cells resemble prolactin cells. The secretory granules of both types are spherical; the diameter of the former is about 340 nm, whereas that of the latter is about 440 nm. ACTH cells are polygonal in shape with secretory granules, about 180 nm in diameter, scattered throughout the cytoplasm. TSH cells, which are spherical in shape, contain the smallest secretory granules, 150 nm in diameter. The highly electron-dense LH cells contain numerous secretory granules about 210 nm in diameter. Their nuclei are irregular with incisures. Thus, the anterior pituitary cells of the goat are ultrastructurally characteristics and species-specific.

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Granulated folliculo-stellate cells and growth hormone cells immunostained with anti-S 100 protein serum in the pituitary glands of the goat

1984

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Goat pituitary glands were immunohistochemically studied with antisera for bovine S-100 protein, rat LH beta, FSH, TSH beta, prolactin, ovine GH, and porcine ACTH1-39 by use of the superimposition technique on adjacent sections. Folliculo-stellate (F-S) cells were divided into two categories on the basis of ultrastructural properties: One consisted of a mass of agranular cells in which the pseudolumina were equipped with microvilli and cilia. Elongate gap junctions were often observed among these cells. The other was a group of granulated cells with or without pseudolumina. In this group the gap junctions were shown to be disintegrated. The dense granules 150-250 nm in diameter began to accumulate in the cells. However, neither type of these F-S cells was immunostained for S-100 protein. On the other hand, numerous polygonal, elongate, irregular or stellate cells containing S-100 protein were distributed throughout the gland. Most of them were immunohistochemically identical with the GH cells laden with the secretory granules 250-450 nm in diameter, but some of them were identical to TSH and prolactin cells which immunostained faintly for S-100 protein. This appears to be the first demonstration of GH cells intensely immunostained for S-100 protein.

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Age Related Changes in the Histomorphology of the Adenohypophysis of the Goat

Cited by 3 publications

References 8 publications

Three‐dimensional architecture and distribution of collagen components in the goat hypophysis

Three‐dimensional architecture and distribution of collagen components in the goat hypophysis

Fine structural and immunohistochemical studies of goat adenohypophysial cells

Granulated folliculo-stellate cells and growth hormone cells immunostained with anti-S 100 protein serum in the pituitary glands of the goat

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