Age-Spesific Seroprevalence and Associated Risk Factors for Hepatitis a in Children in Ankara, Turkey

KILIÇARSLAN, Funda; GÜL, Neşe; Arslan, Zafer; Tanır, Gönül

doi:10.1501/jms_0000000048

Cited by 5 publications

(4 citation statements)

References 10 publications

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“…Social determinants of health, such as poverty, poor housing conditions, lack of access to healthcare, can disproportionately affect certain racial or ethnic groups and increase their risk of contracting and transmitting communicable diseases (170)(171)(172)(173). For example, individuals living in crowded and unsanitary conditions are more likely to contract infectious diseases like TB or hepatitis A (206,207). Therefore, surveillance of specific regions of concern may be recommended.…”

Section: Strengths and Limitations Of Cdwsrank Systemmentioning

confidence: 99%

Wastewater surveillance beyond COVID-19: a ranking system for communicable disease testing in the tri-county Detroit area, Michigan, USA

Gentry

Zhao

Faust

et al. 2023

Front. Public Health

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IntroductionThroughout the coronavirus disease 2019 (COVID-19) pandemic, wastewater surveillance has been utilized to monitor the disease in the United States through routine national, statewide, and regional monitoring projects. A significant canon of evidence was produced showing that wastewater surveillance is a credible and effective tool for disease monitoring. Hence, the application of wastewater surveillance can extend beyond monitoring SARS-CoV-2 to encompass a diverse range of emerging diseases. This article proposed a ranking system for prioritizing reportable communicable diseases (CDs) in the Tri-County Detroit Area (TCDA), Michigan, for future wastewater surveillance applications at the Great Lakes Water Authority's Water Reclamation Plant (GLWA's WRP).MethodsThe comprehensive CD wastewater surveillance ranking system (CDWSRank) was developed based on 6 binary and 6 quantitative parameters. The final ranking scores of CDs were computed by summing the multiplication products of weighting factors for each parameter, and then were sorted based on decreasing priority. Disease incidence data from 2014 to 2021 were collected for the TCDA. Disease incidence trends in the TCDA were endowed with higher weights, prioritizing the TCDA over the state of Michigan.ResultsDisparities in incidences of CDs were identified between the TCDA and state of Michigan, indicating epidemiological differences. Among 96 ranked CDs, some top ranked CDs did not present relatively high incidences but were prioritized, suggesting that such CDs require significant attention by wastewater surveillance practitioners, despite their relatively low incidences in the geographic area of interest. Appropriate wastewater sample concentration methods are summarized for the application of wastewater surveillance as per viral, bacterial, parasitic, and fungal pathogens.DiscussionThe CDWSRank system is one of the first of its kind to provide an empirical approach to prioritize CDs for wastewater surveillance, specifically in geographies served by centralized wastewater collection in the area of interest. The CDWSRank system provides a methodological tool and critical information that can help public health officials and policymakers allocate resources. It can be used to prioritize disease surveillance efforts and ensure that public health interventions are targeted at the most potentially urgent threats. The CDWSRank system can be easily adopted to geographical locations beyond the TCDA.

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Section: Strengths and Limitations Of Cdwsrank Systemmentioning

confidence: 99%

Wastewater surveillance beyond COVID-19: a ranking system for communicable disease testing in the tri-county Detroit area, Michigan, USA

Gentry

Zhao

Faust

et al. 2023

Front. Public Health

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“…• Practice of cleaning (we examined the fingernails of the child to decide whether dirty or clean). • Maternal and paternal education which were classified as (did not complete primary, primary, secondary, or tertiary education) • Crowding (numbers of persons living the home) categorized at two levels (> 4 or ≤ 4 persons/home) • Household spaciousness (classified according to the number of the rooms (> 2 or ≤ 2) • Sanitary facilities (the presence of a flush toilet, or pit toilet, or outside house) [20] Complete physical examination was performed including the following:…”

Section: Exclusion Criteriamentioning

confidence: 99%

Frequency of Hepatitis A virus as a cause of anicteric hepatitis in children under 5 years: a common yet under-recognized cause

Yassin

El-Houchi

El-Shafy

et al. 2022

Egypt Pediatric Association Gaz

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Background Hepatitis A is the most common form of acute viral hepatitis in developing countries. In children < 6 years of age, most infections are asymptomatic, and if illness does occur, it is usually anicteric. This study aimed to determine the frequency of HAV in Egyptian children under 5 years presenting with gastroenteritis-like manifestations and to associate the frequency of HAV with social, demographic, and various risk factors. Results Among 450 children aged from 6 months to 5 years of both sexes, presenting with gastroenteritis-like manifestations and anicteric hepatitis, 200/450 children had elevated transaminases (ALT, AST) and were recruited in the study. A total number of 24 (12%) out of 200 children were found to have HAV IgM antibodies. Lower maternal and paternal education, poor sanitary and hygienic conditions, crowding, contaminated water, and lack of sanitary facilities were significantly higher in HAV-positive group (p-value < 0.05). ALT and AST were significantly higher in HAV IgM-positive group (p-value < 0.01). Conclusion HAV infection is common in Egyptian children with gastroenteritis-like manifestations and anicteric hepatitis. Hepatitis A is a vaccine-preventable disease.

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“…Saptamış olduğumuz seroprevalans değerleri, özellikle de 0-14 yaş aralığında saptadığımız % 52 oranındaki seropozitiflik, ülkemizin daha gelişmiş bölgelerinde yapılmış çalışmalarda, aynı yaş aralığından bildirilen prevalans değerlerine göre daha yüksektir. Ülkemizde yapılmış olan diğer çalışmalarda olduğu gibi, bizim ilimizde de yaş ile artan seropozitiflik dikkat çekicidir [16,18,19,[22][23][24][25][26][27][28][29][30][31] (Tablo 2).…”

Section: Introductionunclassified

Adıyaman İlinde Hepatit A Seroprevalansı

Çitil¹,

Sayıner²,

Akgün³

et al. 2015

J Contemp Med

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Sonuçlar: Tüm dünyada hepatit A enfeksiyonunun serolojik prevalansı coğrafik bölgeler arasında değişkenlik göstermektedir. Türkiye gibi orta endemisite bölgelerinde virus maruziyetinin daha çok ileri yaşlarda ortaya çıkması, ortalama enfeksiyon yaşında ve enfeksiyona karşı hassas adölesan yaş grubu birey sayısında önemli miktarda artışa neden olmaktadır. Özellikle ileri yaşlarda enfeksiyon, daha ciddi ve komplikasyonlu seyir göstermektedir. Hepatit A enfeksiyonuna karşı etkin aşılama programlarının uygulanması ile beraber sanitasyon tedbirlerinin alınması ve kaliteli içme suyuna ulaşımın sağlanmasının ilimizdeki HAV infeksiyon riskini azaltacağı kanaatindeyiz.Anahtar Kelimeler: Hepatit A, seroprevalans, Adıyaman ABSTRACT Objective: Hepatitis A is an acute, mostly self-limiting disease of the liver caused by hepatitis A virus (HAV). The goal of the study was to seek the seroprevalence of hepatitis A infection for different age groups in Adıyaman province. Materials and Methods:In this study, the seropositivity of hepatitis A infection of people who had admitted to Adiyaman University training and research hospital and primary care provider from central regions of Adıyaman city from March 2012 to April 2013 were evaluated, retrospectively. Existence of anti-HAV IgG antibodies were studied by macro ELISA devices belonging two different manufacturers (Abbott Laboratories and Roche Diagnostics).Results: One thousand seven hundred twenty male and 1844 female were included the study (a total of 3564 cases). Anti HAV IgG seropositivity was 77,5% (2761/3564). It was determined that the prevalance was increasing with age. This study found no difference in HAV antibody prevalence between men and women.(p>0,05) Conclusion: Hepatitis A infection's serological prevalence profiles vary geographically in the world. In the intermediate endemic areas like Turkey, the latency in the exposure to the virus has constitute a vast number of susceptible adolescents and extremely increased the average age at infection. The severity of illness increases by age. Implement¬ing vaccination programs for HAV infection, as well as improved hygiene, sanitation, and drinking water quality and quantity are associated with decreased risk of HAV infection.

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Age-Spesific Seroprevalence and Associated Risk Factors for Hepatitis a in Children in Ankara, Turkey

Cited by 5 publications

References 10 publications

Wastewater surveillance beyond COVID-19: a ranking system for communicable disease testing in the tri-county Detroit area, Michigan, USA

Wastewater surveillance beyond COVID-19: a ranking system for communicable disease testing in the tri-county Detroit area, Michigan, USA

Frequency of Hepatitis A virus as a cause of anicteric hepatitis in children under 5 years: a common yet under-recognized cause

Adıyaman İlinde Hepatit A Seroprevalansı

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