AgF‐Mediated Electrophilic Amination of Alkoxyarylsilanes with Azodicarboxylates

Abstract

A facile and efficient AgF-mediated electrophilic amination of alkoxyarylsilanes with azodicarboxylates was developed. The reaction proceeds in green solvent under simple and mild conditions to generate the corresponding aryl hydrazines. AgF acts both as a stoichiometric fluoride source and a reagent for transmetalation to the arylsilver intermediate that eventually reacts with azodicarboxylates to provide aryl hydrazines.

NiH-catalyzed C–N bond formation: insights and advancements in hydroamination of unsaturated hydrocarbons

“…The formation of carbon-nitrogen (C-N) bonds holds a central position in organic synthesis, paving the way for the production of diverse, biologically relevant molecules. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Among the various techniques available for C-N bond formation, hydroamination and hydroamidation reactions have emerged as remarkably versatile and robust strategies. [18][19][20][21][22][23][24][25] This process involves the addition of amines or their derivatives to unsaturated carbon-carbon (C-C) bonds, affording essential building blocks efficiently.…”