Textbook of Aging Skin 2015
DOI: 10.1007/978-3-642-27814-3_125-1
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Aging Skin as a Diagnostic Tool for Internal Diseases: A Chance for Dermatology

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Cited by 2 publications
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“…Ultraviolet (UV) radiation is regard as the reason of extrinsically aging [1]. Based on wavelength, solar UV has 3 main components, including UVA (320–400 nm), UVB (280–320 nm), and UVC (<280 nm).…”
Section: Introductionmentioning
confidence: 99%
“…Ultraviolet (UV) radiation is regard as the reason of extrinsically aging [1]. Based on wavelength, solar UV has 3 main components, including UVA (320–400 nm), UVB (280–320 nm), and UVC (<280 nm).…”
Section: Introductionmentioning
confidence: 99%
“…Some of the pathophysiological manifestations of the aged skin are mainly related to an increase in cutaneous oxidative stress and free radical accumulation, together with a gradual decrease in collagen and mucopolysaccharides. These alterations are one of the main reasons for wrinkling and sagging as they result in deep modifications of the extracellular matrix function and the creation of a catalytic microenvironment 1 . The marked loss of fibrillin structures may also contribute to wrinkles by weakening the dermo‐epidermal junction.…”
Section: Introductionmentioning
confidence: 99%
“…These alterations are one of the main reasons for wrinkling and sagging as they result in deep modifications of the extracellular matrix function and the creation of a catalytic microenvironment. 1 The marked loss of fibrillin structures may also contribute to wrinkles by weakening the dermo-epidermal junction. The basement membrane presents a highly interconnected architecture rich in extracellular matrix proteins, such as collagen type IV, laminin, integrins and other adhesion molecules.…”
Section: Introductionmentioning
confidence: 99%