Agreement between capillary and arterial lactate in the newborn

Fauchère, Jean‐Claude; Bauschatz, A.; Arlettaz, Romaine; Zimmermann‐Bär, Urs; Bucher, Hans Ulrich

doi:10.1111/j.1651-2227.2002.tb01645.x

Cited by 32 publications

(16 citation statements)

References 17 publications

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“…a Sampling times: 1 = before anesthesia (baseline); 2 = 1 hour after induction of anesthesia; 3 = end of surgery; 4 = after 1 hour in the recovery room; 5 = 4 hours after surgery. Some studies found no difference in the lactate levels sampled from the central vein, pulmonary artery or arterial site, in hemodynamically stable but critically ill patients [8][9][10][11]. Others found an arteriovenous lactate level discrepancy [12] or reported that lactate level may be higher in blood collected from the inferior vena cava [13].…”

Section: Discussionmentioning

confidence: 98%

The importance of blood sampling site for determination of hemoglobin and biochemistry values in major abdominal and orthopedic surgery

Evron

Tress

Ezri

et al. 2007

Journal of Clinical Anesthesia

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Section: Discussionmentioning

confidence: 98%

The importance of blood sampling site for determination of hemoglobin and biochemistry values in major abdominal and orthopedic surgery

Evron

Tress

Ezri

et al. 2007

Journal of Clinical Anesthesia

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“…All blood gases obtained during the first 24 h of life were retrieved from patient's records, and a lactate value was available for each sample. This included arterial, capillary and venous samples [6,13,16].…”

Section: Methodsmentioning

confidence: 99%

Day 1 serum lactate values in preterm infants less than 32 weeks gestation

2009

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Base deficit and serum lactate concentrations may be important prognostic indicators in preterm infants. We sought to (1) determine the relationship between day 1 serum lactate values and base deficit and (2) determine the relationship between day 1 biochemical parameters and adverse outcome in preterm infants <32 weeks. This was a retrospective study of all patients less than 32 weeks gestation admitted to neonatal intensive care unit over a 6-month period. All blood gases performed during the first 24 h post delivery were analysed. Adverse outcome was defined as death, severe (grade 3 or 4) intraventricular haemorrhage or periventricular leukomalaica on cranial ultrasonography. Patients were excluded if there was a known lethal malformation or cardiac defect. Seventy-two infants had a total of 473 lactate levels performed in the first 24 h. Mean (SD) gestational age was 29 (2.3) weeks, mean (SD) birth weight 1.28 (0.42) kg. Mean (SD) lactate values in first 6 h was 4.63 (3.69), at 12 h 3.08 (2.6), at 18 h 2.47 (2.68) and 2.08 (2.74) mmol/l at 24 h. There was a strong correlation between lactate values and base deficit values (R value 0.8, p < 0.01). Mean base deficit values at 6 h were 5.9 (4.5), at 12 h 3.8 (3.9), at 18 h 3.6 (3.1) and at 24 h 4.1 (3.8) mmol/l. A single lactate value greater than 5.6 mmol/l had a sensitivity of 100% and specificity of 85% of identifying adverse outcome. Persistently elevated or worsening lactates were associated with adverse outcome. There is a strong correlation between lactate values and base deficit on day 1 of life. Serial lactate measurements greater than 5.6 mmol/l predict adverse outcome and may aid the clinician in bedside decision making.

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“…Furthermore, there is no consensus whether the sample should be drawn from the arterial, peripheral venous, or capillary blood. Most investigators found a satisfactory agreement comparing capillary or venous lactate levels with arterial levels (25)(26)(27)(28). In our opinion, such sampling should therefore be encouraged as patient undergoes this procedure with a minimal risk and inconvenience.…”

Section: Discussionmentioning

confidence: 99%

“…Blood lactate levels are frequently measured, usually to detect tissue hypoxia (24)(25)(26)(27). However, the blood lactate monitoring in critically ill patient remains controversial considering the risk assessment.…”

Section: Discussionmentioning

confidence: 99%

Can a single lactate value predict adverse outcome in critically ill newborn?

Simovic¹,

Stojkovic²,

Savic³

et al. 2015

BLL

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OBJECTIVES: The aim of this study was to investigate the role of the lactic acidosis, as an early predictor of signifi cant consequences and/or a fatal outcome in term neonates after a perinatal asphyxia. BACKGROUND: Severe perinatal asphyxia can generate multiple organ dysfunction and neonatal mortality. METHODS: In routine clinical practice, after an admission to the Intensive Care Unit, lactate concentration was determined in capillary blood samples during the fi rst one to six hours after birth in 55 term newborns with the post-asphyxial hypoxic-ischemic encephalopathy. The control group consisted of 36 healthy term neonates randomly selected in the maternity ward at the Gynecology and Obstetrics Clinic. RESULTS: Signifi cantly higher concentrations of lactate (p < 0.0005) were observed in term neonates with post asphyctic syndrome (8.63 ± 4.43 mmol/L) if compared to the control group subjects (1.04 ± 0.36 mmol/L). The increase in lactate level > 8.7mmol/L with 80 % sensitivity and 82 % specifi city indicated the development of the hypoxic-ischemic encephalopathy stage II/III, while the lactate level > 9.95 mmol/L was a predictor of death, with 75 % sensitivity and 74.4 % specifi city. CONCLUSION: Determination of lactate concentrations in serum of term newborns associated with risk factors for the perinatal asphyxia is a useful tool in diagnosing metabolic disorders and ischemic damage, particularly severe clinical forms (Tab. 2, Fig. 3, Ref. 34). Text in PDF www.elis.sk.

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Agreement between capillary and arterial lactate in the newborn

Cited by 32 publications

References 17 publications

The importance of blood sampling site for determination of hemoglobin and biochemistry values in major abdominal and orthopedic surgery

The importance of blood sampling site for determination of hemoglobin and biochemistry values in major abdominal and orthopedic surgery

Day 1 serum lactate values in preterm infants less than 32 weeks gestation

Can a single lactate value predict adverse outcome in critically ill newborn?

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