AIEgens for dark through-bond energy transfer: design, synthesis, theoretical study and application in ratiometric Hg²⁺ sensing

Abstract

A novel dark through-bond energy transfer (DTBET) strategy is proposed and applied as the design strategy to develop ratiometric Hg2+ sensors with high performance.

In vivo Visualization of the Process of Hg2+ Bioaccumulation in Water Flea Daphnia carinata by a Novel Aggregation‐Induced Emission Fluorogen

“…Jiang et al [21] establishedalinear function between PL intensity and Hg 2 + concentration with only the PL intensity at 595 nm considered, which may be less accurate than using the PL intensity ratio (I 595 /I 480 )b ecauseo ft he different background signals generated at differentm easurements. Cheng et al [20] suggested that the relationships between I 595 /I 480 values and Hg 2 + concentrations should be used. The result of the present study was similar to that of Cheng et al, [20] in that the intensity ratio of I 595 /I 480 increased from 0.17 to 1038.6 when the amount of Hg 2 + increased from 1t o2equiv in the solution, which is an ennormous magnifying factor (> 6100-fold);h owever,c urve fitting was not performed in theirs tudy.…”

“…Cheng et al [20] suggested that the relationships between I 595 /I 480 values and Hg 2 + concentrations should be used. The result of the present study was similar to that of Cheng et al, [20] in that the intensity ratio of I 595 /I 480 increased from 0.17 to 1038.6 when the amount of Hg 2 + increased from 1t o2equiv in the solution, which is an ennormous magnifying factor (> 6100-fold);h owever,c urve fitting was not performed in theirs tudy. [20] In this study,t hen, the function for Hg 2 + concentration with AIEgen PL intensity was established for the firsttime by statistical analysis.…”

“…In vivo visualization and absorption of Hg 2 + + dynamics in D. carinata TPE-RNS based AIEgens have been used previously for Hg 2 + detection in live cells. [20] The potential Hg 2 + sensing performance of TPE-RNS in solutione ncouraged us to evaluate their use for Hg 2 + imaging in small aquatic animals. The control D. carinata,a ss hown in Figures 2a and S3 a, without Hg 2 + and AIEgens, showed no fluorescent signals, like the D. carinata exposed to Hg 2 + withoutA IEgens, as showni nF igures 2b and S3 b.…”

A General Strategy for Through‐Bond Energy Transfer Fluorescence Probes Combining Intramolecular Charge Transfer: A Silyl Ether System for Endogenous Peroxynitrite Sensing

“…[1] Thus, there is no requirement for substantial spectral overlap between the donor emission and acceptora bsorbance, [2] leading to al arge pseudo-Stokes shifts (PSS) and emission shift, which is favorable to avoid self-quenching andf luorescence detectione rrors becauseo fe xcitation back-scattering effects. Althoughn umerousr atiometric fluorescence probes have been implemented with TBET mechanism, thesep robes are predominantly based on spirolactam ring-opening to sensing ions or molecules (Figure 1a), such as Hg 2 + ions, [4][5][6][7][8][9][10][11][12][13] Cu 2 + , [14][15][16] Pd 2 + , [17] Sn 2 + , [18] Ce 4 + , [19] À OCl, [20][21][22][23] picric acid [24] and so on. Althoughn umerousr atiometric fluorescence probes have been implemented with TBET mechanism, thesep robes are predominantly based on spirolactam ring-opening to sensing ions or molecules (Figure 1a), such as Hg 2 + ions, [4][5][6][7][8][9][10][11][12][13] Cu 2 + , [14][15][16] Pd 2 + , [17] Sn 2 + , [18] Ce 4 + , [19] À OCl, [20][21]…”

Boosting Non‐Radiative Decay to Do Useful Work: Development of a Multi‐Modality Theranostic System from an AIEgen

“…[3,4] Concurrently,n on-radiative decay is notorious in the area of luminescence studies,and scientists have devoted great efforts to suppress non-radiative decay for boosting luminescent efficacy.H owever,t he complete restriction of non-radiative decay cannot be achieved. [6] If so,h ow do we promote the probability of non-radiative decay of excited states? [6] If so,h ow do we promote the probability of non-radiative decay of excited states?…”