Airborne allergic contact urticaria from methylhexahydrophthalic anhydride and hexahydrophthalic anhydride

Occupational contact urticaria: Australian data

“…7 Since CU was first defined, there has been a steady increase in the number of case reports describing new causes and these have been extensively reviewed. 3,4,8 Despite individual case reports, [9][10][11][12][13][14][15][16][17][18][19] there remains limited information on the epidemiology of occupational CU (OCU), [20][21][22][23] with the exception of extensive literature on natural rubber latex (NRL) allergy. 24,25 We have undertaken a review of all of the cases of CU diagnosed at the Occupational Dermatology Clinic in Melbourne since 1993.…”

An update on airborne contact dermatitis

“…• Contact urticaria syndrome (also extracutaneous effects such as conjunctivitis, rhinitis, and respiratory symptoms) due to latex (142), Ficus benjamina (147), Morus alba (mulberry) pollen (148), tropical woods (28), potato (149), chironomids (150), the chemicals methylhexahydropthalic and methyltetrahydro‐phthalic anhydrides (151, 152), 2‐(2‐butoxyethoxy)‐ethanol (153), and ethylenediamine (154).…”

Occupational contact urticaria from diglycidyl ether of bisphenol A epoxy resin

“…Recently we reported a case of occupational contact urticaria from methyl hexahydrophthalic anhydride (8) in which a similar enhancement of the contact urticaria reaction was provoked by topical alcohol. We suggest that if the provocation test with low‐molecular‐weight chemicals or other substances is negative, a contact urticaria provocation test with alcohol (CUPTA) should be performed (8). When performing skin provocation tests the same precautions must be taken to avoid systemic reactions, including anaphylaxis, as with prick testing.…”

“…Plastics and glues (5), a phenol–formaldehyde resin series, and a diisocyanate series were negative. Skin prick tests (6) with an environmental allergen series, ER series (2), phthalic anhydrides (7, 8), diisocyanates, and polyesters (7) were negative.…”

“…provoked dense wheal formation in 20 min, with a more intense reaction at 60 min. The exposed area was then wiped with an alcohol solution (Neo‐Amisept Onion Pharma, Espoo, Finland) as previously described (8) provoking an intensified contact urticaria reaction. Prick tests and provocation tests with the hardening compound and other compounds (e.g.…”