AKTIVITAS ANTIBAKTERIAL EKSTRAK ETANOL DAN REBUSAN SARANG SEMUT (Myrmecodia sp.) TERHADAP BAKTERI Escherichia coli

Roslizawaty,; Ramadani, Nita Yulida; Fakhrurrazi,; Herrialfian,

doi:10.21157/j.med.vet..v7i2.2938

Cited by 9 publications

(6 citation statements)

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“…Phytochemical analysis also revealed the presence of alkaloids, flavonoids, saponins, tannins, terpenoids, and carotenoids in the Leda wood extract, all of which have antibacterial properties based on previous studies [20,43]. Tannin compounds, found in Leda wood extract, have antibacterial effects against various bacterial species [44]. Their antibacterial activity is related to the inhibition of enzymes like cellulase, pectinase, and xylonase.…”

Section: Antibacterial Analysis Of Leda Medicinal Plants Againstmentioning

confidence: 82%

Antioxidant and Anti-Bacterial Activity of Medicinal Plant Leda (Eucalyptus deglupta Blume) Extract

Hapid,

Ariyanti,

Erniwati

et al. 2024

IJDNE

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Microbial infection is a prevalent global ailment, accounting for approximately 85% of deaths caused by infectious diseases such as diarrhea, acute respiratory infections, measles, AIDS, tuberculosis, and diarrhea. Therapeutic agents are a specific type of antimicrobial agents used to treat infections. Antimicrobial chemicals are compounds that can inhibit the growth or kill microbes. Leda (Eucalyptus deglupta Blume) is a medicinal plant with potential as a safe antimicrobial. The Kaili people residing near the Lore Lindu National Park have long used it to treat chronic diseases. This research utilized the ethanol extraction method. The phytochemical analysis included tests for alkaloids, triterpenoids, steroids, saponins, phenols, flavonoids, and quinones. The antioxidant activity was measured using the free radical capture method with 1,1-diphenyl-2-picrylhydrazyl (DPPH). The anti-bacterial test employed the agar disc diffusion method. The goal of this study was to investigate the antioxidant and anti-bacterial properties of the Leda medicinal plant extract. The results revealed the presence of alkaloid compounds, flavonoids, saponins, tannins, terpenoids, and carotenoids in the Leda extract. The extract from Leda leaves exhibited potential as a natural antioxidant (IC50 value of 120.31 ppm). The inhibition zone ranges of the Leda extract against the growth of Escherichia coli and Staphylococcus aureus bacteria were 12.67 ± 0.5 mm -19.77 ± 0.58 mm and 19.97 ± 0.76 mm -13.63 ± 0.29 mm, respectively. Therefore, Leda extract can be considered a potent antimicrobial agent.

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Section: Antibacterial Analysis Of Leda Medicinal Plants Againstmentioning

confidence: 82%

Antioxidant and Anti-Bacterial Activity of Medicinal Plant Leda (Eucalyptus deglupta Blume) Extract

Hapid,

Ariyanti,

Erniwati

et al. 2024

IJDNE

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“…coli.Bakteri tersebut merupakan salah satu kelompok bakteri Gram negatif.Dinding sel bakteri Gram negatif terdiri atas lapisan peptidoglikan yang tipis dan membran dibagian luar lapisan peptidoglikan.Dinding selnya mengandung sedikit lapisan peptidoglikan dan tidak mengandung asam teikoat, oleh sebab itu dinding sel bakteri Gram negatif lebi rentan terhadap goncangan fisik, seperti pemberian antibiotik atau bahan-bahan antibakteri lainnya (Mpila, Fatimawali and Wiyono, 2012). Senyawa tanin memiliki aktivitas antibakteri, Mekanisme kerja dalam menghambat sel bakteri, senyawa tanin akan mendenaturasi protein sel bakteri (Roslizawaty et al, 2013), Selain senyawa tanin, senyawa saponin juga memiliki aktivitas antibakteri. Mekanisme kerja senyawa saponin sebagai antibakteri yaitu dengan cara menyebabkan kebocoran protein dan enzim di dalam sel bakteri (Taufiq, Yuniarni and Hazar, 2015).…”

Section: Pendahuluanunclassified

PEMANFAATAN INFUSA BUAH JERNANG (Daemonorops draco Bl.) TERHADAP BAKTERI ESCHERICHIA COLI SEBAGAI OBAT ANTIDIARE PADA SUKU TALANG MAMAK PROVINSI RIAU

Cristine

Ramaloka

2020

JOPS

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Indonesia merupakan negara kepulauan dengan beragam suku dan agama di dalamnya.Ragam suku ini mendiami pulau-pulau yang tersebar di seluruh penjuru Indonesia. Undang-undang nomor 5 tahun 2017 Pada pasal 5 menyebutkan objek pemajuan kebudayaan meliputi tradisi lisan, manuskrip, adat istiadat, ritus, pengetahuan tradisional , teknologi tradisional, seni, bahasa permainan rakyat dan olahraga tradisional. Dewasa ini berbagai bidang pengobatan semakin mengalami perkembangan, termasuk bidang pengobatan tradisional. Tujuan penelitian adalah untuk mengetahui besarnya zona hambat infusa buah Jernang (Daemonorops draco Bl) dalam menghambat pertumbuhan Escherichia coli secara in vitro dan untuk membuktikan apakah infusa buah Jernang yang dipakai masyarakat suku Talang Mamak di Bukit Tiga Puluh Provinsi Riau dapat dijadikan obat antidiare. Penelitian dilaksanakan menggunakan metode eksperimental laboratory secara in vitro. Hasil penelitian didapatkan nilai rata-rata zona hambat pada infusa buah Jernang adalah 9,7mm, nilai rata-rata zona hambat antibiotik ciprofloxacin adalah 35,7mm (kontrol positif) dan NaCl 0,9% steril tidak ada zona hambatan (kontrol negatif). Dari penelitian yang telah dilakukan, dapat disimpulkan bahwa infusa buah Jernang (Daemonorops draco Bl.) mempunyai zat aktif dengan adanya diameter zona hambat sebesar 20mm dan ini membuktikan bahwa infusa buah Jernang dapat dipakai sebagai obat antidiare.

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“…Antibiotics like erythromycin, clindamycin, and tetracycline can be used against Propionibacterium acnes bacteria [11]. Nevertheless, the escalating use of antibiotics can contribute to increased bacterial resistance to these agents [12]. To address bacterial resistance to antibacterial agents, research needs to be directed towards discovering more effective agents that do not induce resistance.…”

Section: Introductionmentioning

confidence: 99%

Production, Quality Test, and Activity Evaluation of Methanol Extract and Nanoparticles from Pluchea indica (L.) Leaves as Additives in Natural Soap against Propionibacterium acnes

Saputra,

Wiratama,

Mayangsari

et al. 2024

J. Kim. Sains Apl.

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Pluchea indica (L.) leaves, both in the form of extracts and silver nanoparticles, are known to exhibit antibacterial activity, but they have not been widely utilized in the health sector, especially in dermatology. This study aims to determine the quality test and antibacterial evaluation of natural soap formulated with methanol extract and nanoparticles of Pluchea indica (L.) leaves against Propionibacterium acnes. The synthesis of silver nanoparticles (AgNPs) was conducted using the reduction method, with AgNO3 as a precursor and methanol extract of Pluchea indica (L.) leaves serving as a reducing agent or bioreductor. Natural soap was produced through the cold process method, with a curing period of 3 to 4 weeks. Natural soap, derived from herbal ingredients, was made by combining NaOH, essential oils, and additives such as methanol extract and silver nanoparticles from Pluchea indica (L.) leaves. Quality tests were performed to assess moisture content (MC), fatty acid content, and pH levels. Antibacterial activity was assessed utilizing the well-diffusion method, with various sample concentrations ranging from 1.0 g/mL to 0.0625 g/mL. The quality test results for all soap samples met the Indonesian National Standard (SNI) requirements for acidity, free fatty acids, and moisture content. The bar soap without additives exhibited antibacterial activity, with a maximum inhibition zone of 14.26 mm (at 0.25 g/mL) after 15 hours. Natural soap with methanol extract of Pluchea indica (L.) leaf demonstrated an inhibition zone of 11.49 mm (at 0.0625 g/mL) after 15 hours, while nanoparticle soap exhibited an inhibition zone of 12.77 mm (at 0.25 g/mL) after 12 hours. In summary, all soap samples showed antibacterial activity, indicating the potential of Pluchea indica (L.) leaves as effective antibacterial agents.

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AKTIVITAS ANTIBAKTERIAL EKSTRAK ETANOL DAN REBUSAN SARANG SEMUT (Myrmecodia sp.) TERHADAP BAKTERI Escherichia coli

Cited by 9 publications

References 0 publications

Antioxidant and Anti-Bacterial Activity of Medicinal Plant Leda (Eucalyptus deglupta Blume) Extract

Antioxidant and Anti-Bacterial Activity of Medicinal Plant Leda (Eucalyptus deglupta Blume) Extract

PEMANFAATAN INFUSA BUAH JERNANG (Daemonorops draco Bl.) TERHADAP BAKTERI ESCHERICHIA COLI SEBAGAI OBAT ANTIDIARE PADA SUKU TALANG MAMAK PROVINSI RIAU

Production, Quality Test, and Activity Evaluation of Methanol Extract and Nanoparticles from Pluchea indica (L.) Leaves as Additives in Natural Soap against Propionibacterium acnes

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