AKTIVITAS ANTIOKSIDAN BUAH PINING (Hornstedtia alliacea) DENGAN MENGGUNAKAN METODE DPPH

Gustaman, Firman; Wulandari, Winda Trisna; Nurviana, Vera; Idacahyati, Keni

doi:10.52434/jfb.v11i1.698

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…However, apart from flavonoids and terpenoids, this research also found other secondary metabolite compounds, namely alkaloids and quinones. 13 Differences in plant secondary metabolite content can be influenced by differences in growing areas, altitude, rainfall and soil nutrient conditions. 15 Flavonoids contain aromatic groups which, when reacted with bases, will conjugate and form a yellow color.…”

Section: Discussionmentioning

confidence: 99%

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The Effect of Galoba (Hornstedtia sp.) Fruit Extract on Malondialdehyde (MDA) Serum Level of Hyperglycemic Mice (Mus musculus) Streptozotocin-Induced

Rumengan,

Kusadhiani,

Agustin

2024

dmj

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Background: Hyperglycemia or increased blood sugar levels is a sign of diabetes mellitus. In hyperglycemia, there will be an increase in Reactive Oxygen Species (ROS) in the body so that it will lead to a state of oxidative stress characterized by an increase in malondialdehyde (MDA) levels. Galoba fruit is an endemic fruit in Maluku Province that contains antioxidants. Antioxidants contained in galoba fruit can help endogenous antioxidants to overcome oxidative stress. Objective: This study aims to determine the effect of galoba fruit extract on serum MDA levels of hyperglycemia mice induced by streptozotocin. Methods: This study is an experimental study with post-test only control group design and random sampling. The sample consisted of 24 mice divided into 6 groups, namely normal control (KN), negative control (K-), positive control (K+), treatment 1 (P1), treatment 2 (P2), and treatment 3 (P3). The KN group was only given a standard diet, the K- group was only induced streptozotocin, the K+ group was induced streptozotocin and treated with metformin for 21 days, and the P1, P2, and P3 groups were induced streptozotocin and given galoba fruit extract concentrations of 100%, 75%, and 50% for 21 days. After treatment, the mice were dissected to collect blood serum from the heart of the mice to measure MDA levels. Serum MDA levels were measured by the TBARS method. Results: The average serum MDA levels of the KN, K-, K+, P1, P2, and P3 groups were 358.75 nmol/mg, 1278.75 nmol/mg, 522.08 nmol/mg, 526.16 nmol/mg, 442.66 nmol/mg, and 432.41 nmol/mg. MDA data obtained was then tested with one way ANOVA and obtained a value of p=0.00 (<0.05). Conclusion: Based on the Tukey test, both P1, P2, and P3 have the same effect on reducing serum MDA levels of mice after being induced by streptozotocin with P3 providing the greatest decrease.

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Section: Discussionmentioning

confidence: 99%

“…Based on the description of several research results, the author conducted this research to determine whether giving Galoba fruit extract which contains secondary metabolite compounds as an exogenous antioxidant can affect MDA levels in the serum of hyperglycemic mice. 13…”

Section: Introductionmentioning

confidence: 99%

The Effect of Galoba (Hornstedtia sp.) Fruit Extract on Malondialdehyde (MDA) Serum Level of Hyperglycemic Mice (Mus musculus) Streptozotocin-Induced

Rumengan,

Kusadhiani,

Agustin

2024

dmj

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“…Galoba (Hornstedtia alliacea) merupakan salah satu buah lokal Maluku yang memiliki ciri berbentuk lonjong, kulit buahnya berwarna coklat, sedangkan salut daging buah berwarna hitam dan buah ini memiliki rasa manis dengan kombinasi berasa agak asam. Gustaman et al (2020), mengemukakan bahwa galoba mengandung senyawa metabolit sekunder diantaranya flavonoid, kuinon, monoterpen dan seskuiterpen serta memiliki aktivitas antioksidan sebesar 23,43 ppm. Pemanfaatan galoba di daerah Maluku masih terbatas, pada umumnya masyarakat mengkonsumsinya dalam bentuk segar, belum dilakukan pengolahan lanjut dari buah tersebut.…”

Section: Pendahuluanunclassified

Effect of the Guar Gum Concentration on Organoleptic Characteristics Jelly Drink Galoba

Picauly¹

2022

JASPT

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he aim of the study was to characterize the organoleptic parameters tested were hedonic testing and hedonic quality including color, taste, texture, suction power. The result of the jelly drink organoleptic test was analyzed descriptively. Based on the result of the study, the organoleptic characteristics of the galoba jelly drink, namely for the hedonic test, the color ranged from 2.8 – 3.1 (close to somewhat like to somewhat like), taste 4.0-4.1 (like), texture 3.5-4.0 (rather like to like), suction power ranged from 3.6 -4.0 (rather like to like), and hedonic quality test for color 2.6-3.0 (close to cloudy white – slightly cloudy white), taste 3.5-3.6 (slightly galoba taste), texture 2.8 – 4.0 (textured close to slightly chewy to chewy), and suction power 3.6-4.0 (rather easy to suck up to easy to suck up).

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Formulation and effectivity testing of pining fruit extract gel (Hornstedtia alliacea) for healing burns

et al. 2022

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Background: Pining fruit is a traditional medicinal plant employed to treat burns for its content of active natural ingredients such as flavonoids, tannins, and saponins acting as antioxidants and anti-inflammatory. Objective: The objective of this study was to formulate the best formula for gel preparations and test the effectiveness of pining fruit extract gel preparations for healing burns. Methods: Evaluation tests of the gel preparations included organoleptic, homogeneity, pH, spreadability, and viscosity tests. The gel effectiveness test was conducted in five treatment groups for 14 days. The data were analysed statistically using the one-way ANOVA method followed by the LSD (Least Significant Different) test. Results: The physical evaluation of pining fruit gel preparations, i.e. organoleptic, homogeneity, pH, dispersion, and viscosity tests on all three formulas (F1, F2, and F3), met the requirements. The results of the one-way ANOVA analysis revealed a significant difference in the experimental group with a score of 0.022 (p < 0.05). Hence, the most effective formula for curing burns was F3, with a 1.5% extract concentration and a healing percentage of 19.175%.

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AKTIVITAS ANTIOKSIDAN BUAH PINING (Hornstedtia alliacea) DENGAN MENGGUNAKAN METODE DPPH

Cited by 5 publications

References 8 publications

The Effect of Galoba (Hornstedtia sp.) Fruit Extract on Malondialdehyde (MDA) Serum Level of Hyperglycemic Mice (Mus musculus) Streptozotocin-Induced

The Effect of Galoba (Hornstedtia sp.) Fruit Extract on Malondialdehyde (MDA) Serum Level of Hyperglycemic Mice (Mus musculus) Streptozotocin-Induced

Effect of the Guar Gum Concentration on Organoleptic Characteristics Jelly Drink Galoba

Formulation and effectivity testing of pining fruit extract gel (Hornstedtia alliacea) for healing burns

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