AKTIVITAS EKSTRAK KULIT BUAH PISANG AMBON  (Musa paradisiaca var. Savientum L.) TERHADAP PERTUMBUHAN Escherichia coli

Rachmawati, Dwi; Salasa, Alfrida Monica; Miri, Resti

doi:10.32382/mf.v13i2.830

Cited by 2 publications

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“…The experimental setup included the use of a ketoconazole solution with batch number 4591 as the positive control. Additionally, distilled water served as the negative control (Maulana et al 2020). After a 24-hour incubation period, the measurement of the generated inhibition zone was conducted.…”

Section: Methodsmentioning

confidence: 99%

Antifungal Activity of Endophytic Bacteria Isolated from Miana Plants (Coleus scutellarioides (L.) Benth.) against Candida albicans

Melda Yunita,

Ruth Magdalena Lumbantobing,

Ritha Tahitu

2023

FMI

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Highlights: 1.Due to the adverse effects associated with current antifungal drugs, research on traditional medicine is necessary to explore other options for candidiasis treatment.2.Following the findings of this study, it is recommended to conduct further research by incorporating Coleus scuttellarioides filtrate into the growth medium, since this may improve bacterial growth by producing optimal secondary metabolites. Abstract Candida albicans is the most common organism responsible for both mucosal and systemic infections, accounting for approximately 70% of fungal infections worldwide. Miana, scientifically known as Coleus scuttellarioides (L.) Benth., is recognized for its use in traditional medicinal practices. Miana plants contain endophytic bacteria that possess the ability to produce secondary metabolites with potential antifungal agents. The objective of this study was to assess the antifungal activity of nine endophytic bacteria isolates derived from Coleus scuttellarioides against Candida albicans. This study was laboratory-based qualitative experimental research that applied the Kirby-Bauer diffusion method and several modifications. The Candida albicans specimens were spread throughout the entire potato dextrose agar medium. Afterwards, paper discs that had been soaked in a liquid culture of endophytic bacterial isolates were carefully placed on the surface of the medium. The complete setup was then incubated for 1–2 days. The potential antifungal activity of endophytic bacteria was assessed by observing the emergence of a clear zone surrounding their growth, which would indicate inhibition. An additional observation was performed in the follow-up test, involving the use of Sabouraud dextrose agar medium to confirm the initial test result. The results from the inhibitory test revealed that none of the bacterial isolates exhibited any inhibition zone. Conversely, ketoconazole as the positive control showed an inhibition zone with an average diameter of 28.5 mm. In conclusion, endophytic bacterial isolates obtained from Coleus scuttellarioides have no discernible antifungal properties against Candida albicans. This study implies that ketoconazole remains effective in treating infections caused by Candida albicans.

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Section: Methodsmentioning

confidence: 99%

Antifungal Activity of Endophytic Bacteria Isolated from Miana Plants (Coleus scutellarioides (L.) Benth.) against Candida albicans

Melda Yunita,

Ruth Magdalena Lumbantobing,

Ritha Tahitu

2023

FMI

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“…25 Peningkatan konsentrasi ekstrak daun mangga (Mangifera Indica L.) mempengaruhi diameter zona hambat yang terbentuk sehingga kemampuan tersebut berbeda-beda dalam menghambat pertumbuhan jamur Candida albicans. 26 Kecepatan difusi suatu bahan antimikroba dapat dipengaruhi oleh perbandingan jumlah pelarut dan zat yang terlarut sehingga dalam keadaan tertentu bahan antimikroba dengan konsentrasi rendah dapat bekerja secara optimal. Bahan dengan konsentrasi rendah memiliki jumlah pelarut yang lebih banyak dibandingkan dengan zat terlarut.…”

Section: Hasilunclassified

Daya hambat ekstrak daun mangga (Mangifera indica l.) terhadap pertumbuhan Candida albicans: studi deskriptif

Sari,

Alamsyah,

Kornialia

2024

Padjadjaran J Dent Res Students

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AKTIVITAS EKSTRAK KULIT BUAH PISANG AMBON (Musa paradisiaca var. Savientum L.) TERHADAP PERTUMBUHAN Escherichia coli

Cited by 2 publications

References 0 publications

Antifungal Activity of Endophytic Bacteria Isolated from Miana Plants (Coleus scutellarioides (L.) Benth.) against Candida albicans

Antifungal Activity of Endophytic Bacteria Isolated from Miana Plants (Coleus scutellarioides (L.) Benth.) against Candida albicans

Daya hambat ekstrak daun mangga (Mangifera indica l.) terhadap pertumbuhan Candida albicans: studi deskriptif

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