Alcohol consumption and cardiovascular diseases in rural China

Zhao, Li; Bai, Yunlong; Guo, Xiaofan; Zheng, Liqiang; Sun, Yingxian; Roselle, Abraham Marria

doi:10.1016/j.ijcard.2016.04.095

Cited by 71 publications

(40 citation statements)

References 43 publications

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“…The present study was based on a large scale crosssectional epidemiological survey known as NCRCHS that conducted from January 2012 to August 2013. The detailed design and rationale of NCRCHS were fully described elsewhere [25]. 14,016 permanent residents (age ≥ 35 years) from rural areas of Northeast China were recruited to assess the incidence, prevalence, and natural history of cardiovascular risk factors.…”

Section: Study Populationmentioning

confidence: 99%

Impact of monocyte to high-density lipoprotein ratio on prevalent hyperuricemia: findings from a rural Chinese population

Chen

Shi

et al. 2020

Lipids Health Dis

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Background: Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a novel inflammatory marker that has been used to predict various inflammation-related diseases. This study aims to explore the association between MHR and prevalent hyperuricemia in a rural Chinese population. Methods: 8163 eligible participants (mean age: 54.13 years, males: 45.71%) from northeast China were enrolled in this cross-sectional study between 2012 to 2013. MHR was determined as blood monocyte count ratio to highdensity lipoprotein cholesterol concentration. Results: The prevalence of hyperuricemia was 12.86%. After adjusting for potential confounding factors, per SD increase of MHR caused a 25.2% additional risk for hyperuricemia, and the top quartile of MHR had an 82.9% increased risk for hyperuricemia compared with the bottom quartile. Additionally, smooth curve fitting and subgroup analyses showed a linear and robust association between MHR and prevalent hyperuricemia respectively. Finally, after introducing MHR into the established model of risk factors, the AUC displayed a significant improvement (0.718 vs 0.724, p = 0.008). Furthermore, Category-free net reclassification improvement (0.160, 95% CI: 0.096-0.224, P < 0.001) and integrated discrimination improvement (0.003, 95% CI: 0.002-0.005, P < 0.001) also demonstrated significant improvements. Conclusions: The present study suggests that MHR was positively and independently correlated with prevalent hyperuricemia among rural Chinese adults. Our results also implicate an important value for MHR in optimizing the risk stratification of hyperuricemia.

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Section: Study Populationmentioning

confidence: 99%

Impact of monocyte to high-density lipoprotein ratio on prevalent hyperuricemia: findings from a rural Chinese population

Chen

Shi

et al. 2020

Lipids Health Dis

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“…Methods of this study have been described elsewhere [13]. The present study applied 'NCRCHS', which is a large-scale epidemiological follow-up study in Liaoning Province, located in northeast China.…”

Section: Study Populationmentioning

confidence: 99%

“…A standardized questionnaire was used to collect demographic variables (sex, age, and ethnicity), lifestyle risk factors (smoking, drinking status and salt intake), history of heart disease and any medication used in the two weeks prior to the survey. Currently smoking has been defined as at least one cigarette per day and for at least one year [13]. Alcohol consumption was defined as the weekly consumption of beer, wine and hard liquor, converted into mL of alcohol.…”

Section: Measurementsmentioning

confidence: 99%

“…Alcohol consumption was defined as the weekly consumption of beer, wine and hard liquor, converted into mL of alcohol. Current drinking was defined as more than 1 drink/day for women and more than 2 drinks/day for men during the last year [13]. In rural areas of China, 84% of consumed salt is added during cooking or as a preservative of foods prepared in the fall season for consumption through the spring season (salted foods).…”

Section: Measurementsmentioning

confidence: 99%

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Temporal relationship between body mass index and triglyceride-glucose index and its impact on the incident of hypertension

Xie

Guo

Zhao

et al. 2019

Nutrition, Metabolism and Cardiovascular Diseases

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Background and aims: Obesity and insulin levels can influence each other by metabolism. However, their temporal sequences and influence on hypertension are generally unknown, especially in Chinese adults. Recently, some scholars have proposed that triglyceridesglucose index (TyG) is an important indicator of insulin resistance. The study aims to describe the relationship between body mass index (BMI) and TyG index and its impact on hypertension. Methods and results: A total of 4081 adults (56.33% women) without antihypertensive, hypoglycemic or lipid-lowering medications were selected for the present study. Measurements of BMI and TyG index were obtained twice from 2012 to 2017. Cross-lagged panel analysis was used to describe the temporal sequences between BMI and TyG index, and the effect of their temporal relationship patterns on hypertension was explored through mediation analysis. After adjusting for confounding factors (age, sex, ethnicity et al.), the cross-lagged path coefficient from baseline BMI to follow-up TyG (r 2 Z 0.135, P < 0.001) was significantly greater than the path coefficient from baseline TyG to follow-up BMI (r 1 Z 0.043, P < 0.001), and P < 0.001 for the difference between r 1 and r 2. Furthermore, the sensitivity analyses between women and men revealed identical findings. In addition, TyG index mediation effect on BMI-hypertension was estimated to be 38.45% (P < 0.001) in total population, 25.24% in women and 57.35% in men. Conclusion: These results provided evidence that the temporal relationship between BMI and insulin resistance is reciprocal and a higher BMI precedes hyperinsulinemia in Chinese adults. This relationship plays an essential role in the development of hypertension, while there is a difference between women and men.

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“…Daily or weekly alcohol consumption alone is not adequate to describe the relationship between alcohol consumption and incident CHD and drinking pattern may play an important role in the alcohol-CHD relationship [16]. In addition, there is limited evidence on association between drinking pattern and CHD incidence among the middle-aged and older population in China [17]. …”

Section: Introductionmentioning

confidence: 99%

Association of drinking pattern with risk of coronary heart disease incidence in the middle-aged and older Chinese men: Results from the Dongfeng-Tongji cohort

Zhang

Yuan

et al. 2017

PLoS ONE

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BackgroundEpidemiologic studies have found that moderate alcohol consumption was associated with a decreased risk of coronary heart disease (CHD) incidence. Nevertheless, whether the drinking pattern is associated with CHD incidence still remains inconclusive.MethodsWe included 8,469 Chinese men aged 45–81 years, who were free of CHD, stroke, or cancer at baseline from Dongfeng-Tongji cohort. A semi-structured questionnaire was used to collect information on alcohol consumption and other covariates. Cox proportional hazard regression model was applied to estimate the multivariable-adjusted hazard rations (HRs) and 95% confidence intervals (95% CIs).ResultsDuring an average of 4.36 years of follow-up, we identified 959 incident CHD events. Compared with non-drinkers, the multivariable-adjusted HR (95% CI) of CHD incidence was 0.84 (0.71–0.98) in current drinkers. With respect to drinking pattern, men who consumed 20.01–40 grams ethanol once a time had a 24% lower risk of incident CHD (HR = 0.76, 95% CI = 0.62, 0.94) compared with non-drinkers. The adjusted HRs (95% CI) of CHD incidence were 0.80 (0.65, 0.99), 1.02 (0.84, 1.22), and 0.75 (0.59–0.96) in subjects who consumed 0.01–10, 10.01–30, and > 30 grams ethanol per day, respectively. Participants who consumed 20.01–40 grams ethanol per time with less than 5 times per week had the lowest risk of CHD incidence (HR = 0.73, 95% CI = 0.52, 0.96). No significant associations were observed between type or frequency of alcohol consumption and CHD incidence.ConclusionsDrinking was associated with a lower risk of CHD incidence in middle-aged and older Chinese men and moderate quantity of ethanol amounts once a time with lower frequency could been considered as a healthy drinking pattern, which might modify the relationship between alcohol consumption and incident CHD.

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Alcohol consumption and cardiovascular diseases in rural China

Cited by 71 publications

References 43 publications

Impact of monocyte to high-density lipoprotein ratio on prevalent hyperuricemia: findings from a rural Chinese population

Impact of monocyte to high-density lipoprotein ratio on prevalent hyperuricemia: findings from a rural Chinese population

Temporal relationship between body mass index and triglyceride-glucose index and its impact on the incident of hypertension

Association of drinking pattern with risk of coronary heart disease incidence in the middle-aged and older Chinese men: Results from the Dongfeng-Tongji cohort

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