Objective: Alcohol consumption may play a role in the development of obesity but the relationship between alcohol and weight is still unclear. The aim of our study was to assess the cross-sectional association of intakes of total alcohol and of specific alcoholic beverages (wine, beer and spirits) with waist-to-hip ratio (WHR) and body mass index (BMI) in a large sample of adults from all over France. Design: Cross-sectional. Setting: Participants were free-living healthy volunteers of the SU.VI.MAX study (an intervention study on the effects of antioxidant supplementation on chronic diseases). Subjects: For 1481 women aged 35 -60 years and 1210 men aged 45-60 years, intakes of total alcohol and specific alcoholic beverages were assessed by six 24-hour dietary records. BMI and WHR were measured during a clinical examination the year after. Results: A J-shaped relationship was found between total alcohol consumption and WHR in both sexes and between total alcohol consumption and BMI in men only (P , 0.05). The same relationships were observed with wine (P , 0.05); men and women consuming less than 100 g day 21 had a lower BMI (men only) and WHR than non-drinkers or those consuming more. Overweight and obesity are major health problems in developed countries and are strongly related to risk of many chronic diseases such as cardiovascular diseases and cancers 1 . Alcohol is the second most energy-dense macronutrient and has an appetite-enhancing effect, which may lead to an increase in energy intake, inducing an increase in body mass index (BMI) 2,3 . Most studies indeed report that moderate alcohol drinkers do not compensate for the energy delivered by alcohol through a decrease in non-alcohol food intake, but tend to consume more energy than non-drinkers 2 -7 . It is also known that alcohol suppresses the oxidation of fat, thus favouring fat storage 8 . Hence, we would expect to find a positive relationship between alcohol consumption and obesity. However, the links between alcohol consumption and obesity or body fat distribution are more complex and often paradoxical. In several studies, despite their higher caloric intakes, drinkers were not more obese than nondrinkers 4,9 . In fact, inverse associations between alcohol and BMI have been shown in women 2,4,8,10 -12